Table of Contents

Contributors     vii
Preface     ix
Obituary     xi
Strain Theory of Malaria: The First 50 Years   F. Ellis McKenzie   David L. Smith   Wendy P. O'Meara   Eleanor M. Riley     1
Introduction     2
Background     3
Clinical Virulence     6
Reaction to Anti-malarial Remedies     9
Infectivity     12
Antigenic Properties     16
Latency and Relapse     28
Summary and Discussion     33
Acknowledgements     38
References     38
Advances and Trends in the Molecular Systematics of Anisakid Nematodes, with Implications for their Evolutionary Ecology and Host-Parasite Co-evolutionary Processes   Simonetta Mattiucci   Giuseppe Nascetti     47
Introduction     49
Molecular Systematics of Anisakid Nematodes     51
The Current Taxonomy     55
Phylogenetic Systematics of Anisakid Nematodes     91
Genetic Differentiation in Anisakids     100
Host-Parasite Cophylogeny     108
Host Preference, Ecological Niche and Competition     114
Anisakids as Biological Indicators     119
Conclusions and Identification of Gaps in Our Knowledge of Anisakids to be Filled by Future Research     130
Acknowledgements     137
References     137
Atopic Disorders and Parasitic Infections   Aditya Reddy   Bernard Fried     149
Introduction     150
Atopic Disorders     151
Relationship of Parasites to Atopic Disorders     154
Laboratory Studies on Atopy Using Selected Parasites and Rodent Models     175
Concluding Remarks     182
References     184
Heartworm Disease in Animals and Humans   John W. McCall   Claudio Genchi   Laura H. Kramer   Jorge Guerrero   Luigi Venco     193
Introduction (Biology and Life Cycle)     195
Epidemiology in Domestic and Wild Hosts     199
Pathogenesis, Immunology and Wolbachia Endosymbiosis     209
Canine Heartworm Disease     222
Feline Heartworm Disease     233
Heartworm Disease in Ferrets     253
Human Dirofilariosis     258
Emerging Strategies in Heartworm Treatment and Control     263
Acknowledgments     265
References     265
Index      287
Contents of Volumes in This Series     295