50 Studies Every Internist Should Know

by Kristopher J. Swiger, Joshua R. Thomas, Michael E. Hochman, Steven D. Hochman

Overview

50 Studies Every Internist Should Know presents key studies that shape today's practice of internal medicine. Selected using a rigorous methodology, the studies cover topics including: preventative medicine, endocrinology, hematology and oncology, musculoskeletal diseases, nephrology, gastroenterology, infectious diseases, cardiology, pulmonology, geriatrics and palliative care, and mental health. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. An illustrative clinical case concludes each review, followed by brief information on other relevant studies. This book is a must-read for health care professionals and anyone who wants to learn more about the data behind clinical practice.

Product Details

ISBN-13:	9780199349937
Publisher:	Oxford University Press
Publication date:	02/12/2015
Series:	Fifty Studies Every Doctor Should Know
Pages:	352
Sales rank:	717,248
Product dimensions:	6.10(w) x 9.10(h) x 0.80(d)

About the Author

Kristopher Swiger, MD is a Resident Physician of Internal Medicine at the Johns Hopkins Hospital in Baltimore, Maryland.

Joshua R. Thomas, MD, MPH is a Cardiology Fellow at Nationwide Children's Hospital and The Ohio State University in Columbus, Ohio.

Michael E. Hochman, MD, MPH is the Medical Director for Innovation at AltaMed Health Services in Los Angeles, California.

Steven Hochman, MPH is a Medical Student at Keck School of Medicine of the University of Southern California in Los Angeles, California.

Table of Contents

Section 1. Preventive Medicine

1. Preventing Diabetes: The Diabetes Prevention Program

2. Dietary Approaches to Stop Hypertension (DASH)

3. Aspirin for the Primary Prevention of Cardiovascular Disease: The Physicians' Health Study and the Women's Health Study

4. Postmenopausal Hormone Therapy: The Women's Health Initiative

5. The Cochrane Review of Screening Mammography

6. The European Randomized Study of Screening for Prostate Cancer

7. Screening for Lung Cancer with Low-Dose Computed Tomography vs. Chest Radiography: The National Lung Screening Trial (NLST)

Section 2. Endocrinology

8. Treating Elevated Blood Sugar Levels in Patients with Type 2 Diabetes: the United Kingdom Prospective Diabetes Study (UKPDS)

9. Intensive versus conservative blood sugar control for patients with type 2 diabetes: the ACCORD trial

10. Intensive vs. Conventional Glycemic Control in Type 1 Diabetes Mellitus (DCCT)

11. Intensive vs. Conservative Blood Pressure Control in Patients with Type 2 Diabetes

Section 3. Hematology and Oncology

12. Choice of Anticoagulant for Prevention of Recurrent Venous Thromboembolism in Patients with Cancer

13. Vena Caval Filters in the Prevention of Pulmonary Embolism in Patients with Proximal Deep-Vein Thrombosis

14. Phase I Study of Imatinib (STI571) in Patients with Chronic Myelogenous Leukemia

Section 4. Musculoskeletal Diseases

15. Magnetic Resonance Imaging for Low Back Pain

16. Early therapy for rheumatoid arthritis: The TICORA Study

Section 5. Nephrology

17. Revascularization vs. Medical Therapy for Renal Artery Stenosis

18. Correcting Anemia in Chronic Kidney Disease: The CHOIR Study

19. Early versus Late Initiation of Dialysis: The IDEAL Trial

Section 6. Gastroenterology

20. Use of IV Albumin in Patients with Cirrhosis and Spontaneous Bacterial Peritonitis

21. Early use of transjugular intrahepatic portosystemic shunt (TIPS) in patients with cirrhosis and variceal bleeding

Section 7. Infectious Diseases

22. Methicillin-Resistant S. aureus Infections among Patients in the Emergency Department

23. Antibiotic Therapy in Exacerbations of Chronic Obstructive Pulmonary Disease

24. Early versus Delayed Antiretroviral Therapy for Patients with HIV: The NA-ACCORD Study

Section 8. Cardiology

25. Statins in Healthy Patients with an Elevated C-Reactive Protein: The JUPITER Trial

26. The Scandinavian Simvastatin Survival Study (4S)

27. Choosing Fist-Line Therapy for Hypertension: The ALLHAT Trial

28. Rate Control versus Rhythm Control for Atrial Fibrillation: The AFFIRM Trial

29. Initial Treatment of Stable Coronary Artery Disease: The COURAGE Trial

30. Early Invasive vs. Conservative Management for Unstable Angina or Non-ST-Elevation Myocardial Infarction: The RITA 3 Trial

31. MADIT II: Prophylactic Defibrillator Implantation in Patients with Low Ejection Fraction Following Myocardial Infarction

32. Captopril in Patients with Left Ventricular Dysfunction after Myocardial Infarction: The SAVE Trial

33. Spironolactone in Advanced Heart Failure: The RALES Trial

34. The African American Heart Failure Trial (A-HeFT)

35. Intraaortic Balloon Support for Myocardial Infarction with Cardiogenic Shock (IABP-SHOCK II)

Section 9. Pulmonary and Critical Care Medicine

36. Intensive versus Conventional Glucose Control in Critically Ill Patients

37. Red Cell Transfusion in Critically Ill Patients: The TRICC Trial

38. Noninvasive Ventilation for Acute Exacerbations of Chronic Obstructive Pulmonary Disease

39. Low Tidal Volume Ventilation in Acute Respiratory Distress Syndrome/Acute Lung Injury

40. Comparison of routine vs. on-demand chest radiographs in mechanically-ventilated adults in the intensive care unit

41. Early Goal-Directed Therapy in Sepsis

42. Dopamine vs. norepinephrine in the treatment of shock

43. Daily Interruption of Sedative Infusions in Critically Ill Patients Undergoing Mechanical Ventilation

44. A Comparison of Four Methods of Weaning Patients from Mechanical Ventilation

Section 10. Geriatrics and Palliative Care

45. Behavioral versus Pharmacological Treatment for Insomnia in the Elderly

46. Treatment of Hypertension in the Elderly

47. Use of feeding tubes in patients with dementia

48. Early Palliative Care in Non-Small-Cell Lung Cancer

Section 11. Mental Health

49. Initial Treatment of Depression

50. Symptom-Triggered vs. Fixed Dose Therapy for Alcohol Withdrawal

Editorial Reviews

"This is a masterful idea, as it draws attention to those areas that are of interest to readers and then moves them into other areas. [...] This is a great book. Weighted Numerical Score: 100 - 5 Stars! " — Doody's

From the Publisher

Reviewer: Vincent F Carr, DO, MSA, FACC, FACP (Uniformed Services University of the Health Sciences)
Description: Much of what is practiced in medicine has been based upon observations made by experienced clinicians and many of these practices were not subjected to research scrutiny. This book highlights the historical background of evidence-based medicine.
Purpose: This book compiles some of the seminal studies that defined the evidence-based practice evolution and, in many cases, the seminal papers upon which our current practice is based.
Audience: The book is intended to help internists and primary care clinicians understand medicine's current environment. The editors are well-known, experienced teachers and clinicians.
Features: The 50 studies are sectioned into various areas of medicine, such as preventive medicine, endocrinology, hematology/oncology, etc. This is a masterful idea, as it draws attention to those areas that are of interest to readers and then moves them into other areas. Some of these studies date back to the late 1980s while others are from as recently as 2010. The time span of these studies shows the progression of research over the years.
Assessment: As an older clinician, I found it interesting to rethink the studies of the past. For younger physicians, this book demonstrates the benefit of reevaluating some preconceptions about practice. This is a great book.

Doody's Review Service