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Overview
Now in a revised and expanded third edition, this case-based guide emphasizes the latest investigative advances in both imaging and molecular diagnostics and new treatment approaches for a wide variety of common and complex endocrine conditions.
Utilizing unique clinical case histories, each main endocrine condition and disorder is curated by a senior Section Editor with an introduction to his or her area covering both physiology and pathophysiology. This introductory chapter is followed by a number of case histories written by invited experts and designed to cover the important relevant pathophysiology, following a consistent chapter format for ease of use, including bulleted objectives, case presentations, review of the diagnosis, lessons learned, and 3-5 multiple-choice review questions. Section headings include the pituitary, thyroid (overactivity, underactivity and cancer) and parathyroid, adrenal disorders, metabolic bone disease, type 2 diabetes, lipid abnormalities, obesity, and pregnancy. Topics new to this edition include PCOS, transgender medicine and the endocrine effects of viral infections.
With a focus on covering major parts of the APDEM curriculum, A Case-Based Guide to Clinical Endocrinology remains a tremendous resource for junior and veteran clinicians alike.
Utilizing unique clinical case histories, each main endocrine condition and disorder is curated by a senior Section Editor with an introduction to his or her area covering both physiology and pathophysiology. This introductory chapter is followed by a number of case histories written by invited experts and designed to cover the important relevant pathophysiology, following a consistent chapter format for ease of use, including bulleted objectives, case presentations, review of the diagnosis, lessons learned, and 3-5 multiple-choice review questions. Section headings include the pituitary, thyroid (overactivity, underactivity and cancer) and parathyroid, adrenal disorders, metabolic bone disease, type 2 diabetes, lipid abnormalities, obesity, and pregnancy. Topics new to this edition include PCOS, transgender medicine and the endocrine effects of viral infections.
With a focus on covering major parts of the APDEM curriculum, A Case-Based Guide to Clinical Endocrinology remains a tremendous resource for junior and veteran clinicians alike.
Product Details
ISBN-13: | 9783030843694 |
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Publisher: | Springer International Publishing |
Publication date: | 01/04/2022 |
Edition description: | 3rd ed. 2022 |
Pages: | 560 |
Sales rank: | 951,726 |
Product dimensions: | 6.10(w) x 9.25(h) x (d) |
About the Author
Terry F. Davies, MB.BS, MD, FRCP, FACE, Florence and Theodore Baumritter Professor of Medicine, Icahn School of Medicine at Mount Sinai, Director, Division of Endocrinology, Diabetes and Bone Diseases, Mount Sinai Beth Israel Medical Center, New York, NY, USA
Table of Contents
Preface v
Contributors xv
The Pituitary Gland
Introduction Pamela U. Freda 3
Pituitary Apoplexy Steven Jon Russell Karen Klahr Miller 9
When and How to Stop Cabergoline Treatment in Microprolactinomas Annamaria Colao 19
Cushing's Disease Kawaljeet Kaur James W. Findling 27
Thyroid Overactivity
Introduction David S. Cooper 37
Amiodarone-Induced Hyperthyroidism Paul Aoun David S. Cooper 41
Interferon-Induced Hyperthyroidism Paul Aoun David S. Cooper 49
Subclinical Hyperthyroidism Due to a Multinodular Thyroid Paul Aoun David S. Cooper 61
Subacute (De Quervain's) Thyroiditis Paul Aoun David S. Cooper 67
Thyroid Underactivity
Introduction Anthony P. Weetman 75
Amiodarone-Induced Hypothyroidism Ramzi Ajjan 77
Autoimmune Hypothyroidism with Persistent Elevation of TSH Amit Allahabadia 85
Hashimoto's Thyroiditis and Type 1 Diabetes Mark P.J. Vanderpump 93
Thyroid Cancer
Introduction Kenneth D. Burman 103
Papillary Thyroid Cancer Nicole Ehrhardt Victor Bernet 109
Metastatic Papillary Thyroid Cancer Henry B. Burch 121
Medullary Thyroid Cancer Jacqueline Jonklaas 127
Follicular Thyroid Carcinoma with Pulmonary and Osseous Metastases Jason A. Wexler Kenneth D. Burman 139
Adrenal
Adrenal Insufficiency Lynn Loriaux 155
Cushing's Syndrome Lynn Loriaux 159
An Incidentally Discovered Adrenal Mass Lynn Loriaux 163
Hyperparathyroidism
Introduction Simon H.S. Pearce 169
Differentiation of Primary Hyperparathyroidism for Familial Benign Hypocalciuric Hypercalcemia Ebaa Al Ozairi 179
Management and Investigation of Acute Hypercalcemia Suresh Vaikkakara Chankramath S. Arun R. Andrew James 183
Evaluation of Complex Primary Hyperparathyroidism Ee Lin Lim Simon H.S. Pearce 187
Evaluation of Hypercalcemia in Infancy Reena Thomas Murthy Korada Timothy D. Cheetham 191
Metabolic Bone Diseases
Introduction Mone Zaidi 197
Osteoporosis Due to Hormonal Withdrawal: Common Mistakes Mone Zaidi Michael Pazianas 203
Osteomalacia: A Cause of Bisphosphonate Failure Michael Pazianas Mone Zaidi 209
Unusual Manifestations of Paget's Disease of Bone Mone Zaidi Michael Pazianas 215
Solid Organ Transplantation, Chronic Renal Impairment, and Skeletal Complications Michael Pazianas Mone Zaidi 223
Endocrine Disorders of Males
Introduction Stephen J. Winters Sathya Krishnasamy 231
Congenital Isolated Hypogonadotropic Hypogonadism Stephen J. Winters Sathya Krishnasamy 233
Klinefelter Syndrome Stephen J. Winters Sathya Krishnasamy 241
Low Testosterone in Obesity and Type 2 Diabetes Stephen J. Winters Sathya Krishnasamy 253
Female Reproduction
Introduction Janet E. Hall 263
Central Hypogonadism Maria A. Yialamas 273
Premature Ovarian Failure Corrine K. Welt 279
Oligomenorrhea and Hyperandrogenemia Sabrina Gill 285
Pregnancy
Introduction Alex Stagnaro-Green 295
Hypertension in Pregnancy and Women with Child-Bearing Potential Lawrence R. Krakoff 299
Hashimoto's Hypothyroidism During Pregnancy Susan J. Mandel 305
Type I Diabetes Mellitus During Pregnancy Carol Levy Gal Omry 309
Type 1 Diabetes
Introduction Ake Lernmark 321
Type 1 Diabetes Onset with Ketoacidosis and Suspected Cerebral Edema Helena E. Larsson Sten-A Ivarsson Ake Lernmark 327
En Passant Diagnosis of Type 1 Diabetes in Infancy Helena E. Larsson Sten-A Ivarsson Ake Lernmark 331
Type 1 Diabetes and Comorbidity of Addison's Disease Helena E. Larsson Sten-A Ivarsson Ake Lernmark 337
Type 2 Diabetes
Introduction Barry J. Goldstein 343
Exenatide in Type 2 Diabetes: Indications and Initiation Vanita Treat Serge Jabbour 347
Insulin Therapy in the Management of Diabetes Mellitus Type 2 Kevin Furlong Intekhab Ahmed 353
Treatment of Type 2 Diabetes Mellitus with Oral Agents Jeremy J. Flood Jeffrey L. Miller 359
Lipid Abnormalities
Introduction Neil J. Stone 369
Combination Drug Therapy in a Case of Severe Hypercholesterolemia Conrad B. Blum 371
A Young Man with Abdominal Pain and Very High Triglycerides: The Chylomicronemia Syndrome Molly C. Carr 379
Roughly Equivalent Lipids in a Middle-Aged Obese Man at Risk for Coronary Disease Stephen R. Crespin 387
Obesity and the Metabolic Syndrome
Introduction Robert T. Yanagisawa Derek LeRoith 395
Metabolic Syndrome Robert T. Yanagisawa Derek LeRoith 399
Polycystic Ovarian Syndrome Michael Magnotti Walter Futterweit 407
Bariatric Surgery Robert T. Yanagisawa Daniel Herron Derek LeRoith 417
Puberty
Introduction Donald Zimmerman 427
Amenorrhea Liuska Pesce Donald Zimmerman 433
Early Puberty and Hyperthyroidism Liuska Pesce Donald Zimmerman 437
Hypothalamic Hamartoma Liuska Pesce Donald Zimmerman 445
Leydig Cell Adenoma Courtney Finlayson Reema Habiloy Donald Zimmerman 453
Prolactinoma Jami Josefson Donald Zimmerman 459
Turner Syndrome Jami Josefson Donald Zimmerman 465
Instructive Rarities
Introduction Jeffrey I. Mechanick 473
Hypothalamic Damage and Obesity Lalita Khaodhiar Caroline M. Apovian 475
Systemic Mastocytosis Michael Kleerekoper Luis Afonso 483
Testosteronoma Kimberley E. Steele Martha A. Zeiger 489
Index 499
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