Advances in Genetics

by Dhavendra Kumar

Overview

Advances in Genetics, Volume 105, provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions.

• Critically analyzes future directions for the study of clinical genetics
• Written and edited by recognized leaders in the field
• Presents new medical breakthroughs that are occurring as a result of advances in our knowledge of genetics

Product Details

ISBN-13:	9780128216859
Publisher:	Elsevier Science
Publication date:	06/13/2020
Series:	Advances in Genetics , #105
Pages:	392
Product dimensions:	6.00(w) x 9.00(h) x (d)

About the Author

Professor Kumar has considerable previous experience in writing and editing books and journals related to genetics and genomics. His books include Genomics and Clinical Medicine and Genomics and Health in the Developing World. He founded and leads the new open access journal Applied and Translational Genomics, published by Elsevier. He has published 40 articles in the journals literature.

Professor Dhavendra Kumar is a Visiting Professor, Genomic Policy Unit, Faculty of Life Sciences and Education, The University of South Wales and Consultant in Clinical Genetics at the University Hospital of Wales, Institute of Medical Genetics, Cardiff University, Cardiff, United Kingdom. He is one of the Consultants for the All Wales Medical Genetics Service and the lead Clinician for Clinical Cardiovascular Genetics. After qualifying in Medicine from the King George’s Medical College, University of Lucknow, India, he completed postgraduate training in Pediatrics with an MD. Since 1980 he has pursued a career in Medical Genetics in the UK. In 1990 he became a Diplomate of the American Board of Medical Genetics. He is a Fellow of the American College of Medical Genetics (FACMG) and as well as Royal Colleges of Physicians (FRCP-London and FRCP-Ireland) and Pediatrics and Child Health (FRCPCH-UK).

In 2015, he was conferred with the higher degree of DSc by his Alma Mater, King George’s Medical University, Lucknow (UP, India) based on his life-time contributions and achievements to genetic and genomic applications in medicine and health.

Table of Contents

1. Genetic determinants of climate-resilience traits in millets Mehanathan Muthamilarasan 2. Host and Pathogen Genetics Underpinning Cryptococcus and Cryptococcosis Rhys Farrer 3. Breeding for virus resistance in tomato: Present status and future perspectives Manoj Prasad 4. Founder variants and population genomes - towards precision medicine Vinod Scaria 5. FMRP ribonucleoprotein complexes and RNA homeostasis Luciana Amaral Haddad 6. Developmental Disorders Caused by Mutation in Genes Encoding Ion Channels Suri Mohnish 7. Recent advances in oomycete genomics David Fitzpatrick 8. Re-examination of prior hypotheses about circadian clock genes and mental health in the light of genome-wide association studies Malcolm von Schantz

What People are Saying About This

From the Publisher

Provides users with cutting-edge reviews on the rapidly evolving field of genetics, including information on recent advancements

Editorial Reviews

4 Stars! from Doody

The latest volume in this series covers a wide range of topics and organisms. Among the areas discussed are the genetics of photoperiodism in plants, developmental genetics of Drosophila, chromosome structure and function, and the genetic basis of disease spanning human disease, relevant mouse models, and gene therapy. The purpose is to provide review articles on topics of current interest in genetics. The volume, like its predecessors, will be useful for students, faculty, and laboratory personnel and lends itself to use for background and preparation teaching and research environments. The articles are accompanied by black-and-white and color illustrations that are well designed and informative. The chapters are well written and informative, with numerous citations to the primary literature. The references are pertinent and include articles published in 1996. It should be in the library of every institution and in the offices of most professional geneticists.

Roger W. Melvold

This is a single topic book, devoted to the organization, structure, and function of polytene chromosomes. This is the last of three volumes (in conjunction with vols. 34 and 37) devoted to polytene chromosomes. In this volume the organization of chromatin in polytene chromosomes is reviewed, as is transcriptional activity, including puff formation, Balbiani rings, and nucleoli. There is also a section on DNA replication in polytene chromosomes, and an evaluation of the literature on molecular organization and expression of the ribosomal RNA genes. Bench scientists and graduate students are the intended audience. There are ten sections rather than chapters, beginning with some general background information, and ending with DNA replication. Each section is subdivided into subsections, but this organization is not reflected in the table of contents, making it difficult to find a description of specific topics. The massive amount of work done by the editors would be more evident if the sections had been divided into chapters, with a detailed table of contents for each chapter. The index is useful, and most topics can be found there, but unfortunately, the overall framework of the book is hidden by the cursory table of contents. This organizational quirk should not deter anyone from using this comprehensive volume. In addition to the text, there is a wealth of illustrations in the form of photographs and diagrams, as well as an extensive array of tables. Many of the photographs are accompanied by interpretative drawings that help illustrate the point. The book contains 146 pages of references, and in conjunction with the earlier volumes is perhaps the most comprehensivebibliography on the literature of polytene chromosomes ever assembled. Extensive references published in English, German, Russian, and several other languages is are included. Anyone working on chromosomes, from bench scientists to graduate students, will want to have this important reference on their bookshelf. It is doubtful that another review of this caliber will be published soon.

Michael Cummings

Praise for previous volumes in the series: "Outstanding both in variety and in the quality of its contributions." –Nature

"Can be highly recommended to geneticists, and biologists in general...will prove to be of high importance for the development of the science of genetics." —Science

From the Publisher