Table of Contents
BACTERIAL BASICS Cell Envelope Protein Production Replication Summary of Bacterial Basics
ANTIBACTERIAL AGENTS Antibiotics That Target the Cell Envelope
β-Lactam Antibiotics
Penicillins Cephalosporins Carbapenems Monobactams
Vancomycin Daptomycin
Antibiotics That Block Protein Production
Rifamycins Aminoglycosides Macrolides and Ketolides Tetracyclines and Glycylcyclines Chloramphenicol Clindamycin Streptogramins Linezolid
Antibiotics That Target DNA and Replication
Sulfa Drugs Quinolones Metronidazole
Antimycobacterial Agents Summary of Antibacterial Agents
DEFINITIVE THERAPY (RIGHT DRUG FOR BUG)
Gram-Positive Bacteria
Staphylococci Pneumococci Other Streptococci Enterococci Other Gram-Positive Bacteria
Gram-Negative Bacteria
Enterobacteriaceae
Pseudomonas Neisseria
Curved Gram-Negative Bacilli Other Gram-Negative Bacteria
Anaerobic Bacteria
Clostridia
Anaerobic Gram-Negative Bacilli
Atypical Bacteria
Chlamydia Mycoplasma Legionella Brucella Francisella tularensis Rickettsia
Spirochetes
Treponema pallidum Borrelia burgdorferi Leptospira interrogans
Mycobacteria
Mycobacterium tuberculosis Mycobacterium avium Complex
Mycobacterium leprae
EMPIRIC THERAPY Pneumonia Urinary Tract Infections Pelvic Inflammatory Disease Meningitis Cellulitis Otitis Media Infective Endocarditis Intravascular-Related Catheter Infections Intra-Abdominal Infections
CLINICAL CASES Case 1
Case 2
Case 3
Case 4
Case 5
Case 6
Case 7
Case 8
Case 9
Case 10
Case 11
Case 12
Answers to Clinical Cases
REVIEW QUESTIONS AND ANSWERS Review Questions Answers to Review Questions
APPENDICES Dosing of Antibacterial Agents in Adults Dosing of Antibacterial Agents in Children Dosing of Antibacterial Agents in Adults with Renal Insufficiency Antibacterial Agents in Pregnancy Generic and Trade Names of Commonly Used Antibacterial Agents Treatment of Infections Caused by Bacterial Agents of Bioterrorism Medical References Literary References Answers to Chapter Questions