Reviewer: Anna B Owczarczyk, MD, PHD (University of Michigan Medical School)
Description: This book provides a practical, efficient, pattern-based approach to lymph node evaluation.
Purpose: The book's purpose is to help trainees approach both normal and abnormal findings in a lymph node based on the affected functional compartment. The authors have reached their stated goals.
Audience: This book is thoughtfully designed specifically for pathology trainees.
Features: Chapter 1 includes a comprehensive introduction to the normal lymph node structure, with sub-sections describing how specimen preparation (i.e., fixation time) and clinical context (i.e., anatomic site) can influence the morphology. The first chapter also briefly touches on how ancillary studies may be helpful to support or confirm histological impressions. The remaining chapters address key nodal compartments (capsule, sinuses, cortex, paracortex) or patterns of effacement (i.e., obliterated nodular patterns, obliterated nodal architecture, and necrosis) in the context of benign and pathological processes. Additionally, the book includes a chapter addressing the essential "pro tips" of immunohistochemical interpretation and case write-up. Finally, before the comprehensive index, there is a self-assessment section (with answers) comprised of approximately five questions per chapter. Each chapter includes features that help trainees systematically evaluate a lymph node, including checklists, tables, "pearls and pitfalls" (to provide practical sign-out lessons that emphasis crucial diagnostic clues, mimics, or hazards), "FAQ" (asked by both trainees and non-hematopathologists), "key features" (summarizing crucial diagnostic elements), "sample notes" for rare or complex diagnoses, and "near misses" (to alert the readers to close calls and provide advice for avoiding them). Finally, references for further reading are included at the end of each chapter. More than 1,500 professional-grade photomicrographs grace the pages, depicting a wide breadth of reactive and neoplastic lymph node processes, including "bread and butter" and rarer conditions alike.
Assessment: This book is exceptionally well organized, visually appealing, and very easy to read. It would make an excellent sign-out resource or boards study tool for pathology trainees at all levels. While other hematopathology textbooks are organized by diagnostic entity, this book is uniquely organized by lymph node compartment. In just under 300 pages, the authors have made the evaluation and sign-out of lymph node cases less daunting and quite enjoyable!