In this book, various contributors describe in great detail the intimate relationship between the immune and endocrine systems. The editor has brought together experts from various fields, and compiled a text that includes reviews of the basic structure and function of the immune system, the role of genetics in the pathogenesis of autoimmune conditions, the nature of various autoantigens, and the influence of sex on autoimmunity. He also reviews the important endocrine diseases that are commonly seen. Although this book is similar to ones previously compiled by the editor, it is the most up-to-date and incorporates much of the research that has been done in the past decade. This book would serve as an excellent reference for researchers, students, and fellows, as well as clinicians who desire a deeper appreciation for the pathogenesis of many of the diseases in the patients they treat. The first three chapters of reviews of mechanisms of self tolerance, immunoregulation of autoimmune disease, and genetic of autoimmune disease provide an excellent foundation for the remainder of the text. Chapter 7 provides an especially interesting review of the role of sex hormones on general immune function. The contributors examine the role of sex hormones in the immune response against various parasitic infections in both mice and humans, as well as nonendocrine autoimmune diseases. They then proceed to examine the various roles of sex hormones on the different aspects of immunity. They manage to make this an informative and interesting topic. I found this text an extremely useful and interesting source. Although the editor doubts that he will edit any similar texts in the future, I hopethat this will prove untrue. With the rapidly expanding knowledge base in both fields, I have no doubt that a new text will soon be required.
Contributors review the latest thinking about theoretical, experimental, and clinical aspects of autoimmune endocrine disorders. They examine the pathogenesis and immunogenesis of these diseases, discuss the role of sex hormones in autoimmunity, and elucidate the nature of autoantigens. They provide clinical detail on a variety of autoimmune endocrinopathies, including autoimmune thyroid disease, Grave's ophthalmopathy and darmopathy, and autoimmune adrenocortical failure. Post-partum autoimmune endocrine syndromes, autoimmune hypophysitis, and polyglandular autoimmune syndromes are discussed, as are techniques of prevention and new immunomodulatory therapeutics. Annotation c. Book News, Inc., Portland, OR (booknews.com)
Reviewer: Varman T. Samuel, MD (University of Chicago Medical Center)
Description: In this book, various contributors describe in great detail the intimate relationship between the immune and endocrine systems.
Purpose: The editor has brought together experts from various fields, and compiled a text that includes reviews of the basic structure and function of the immune system, the role of genetics in the pathogenesis of autoimmune conditions, the nature of various autoantigens, and the influence of sex on autoimmunity. He also reviews the important endocrine diseases that are commonly seen. Although this book is similar to ones previously compiled by the editor, it is the most up-to-date and incorporates much of the research that has been done in the past decade.
Audience: This book would serve as an excellent reference for researchers, students, and fellows, as well as clinicians who desire a deeper appreciation for the pathogenesis of many of the diseases in the patients they treat.
Features: The first three chapters of reviews of mechanisms of self tolerance, immunoregulation of autoimmune disease, and genetic of autoimmune disease provide an excellent foundation for the remainder of the text. Chapter 7 provides an especially interesting review of the role of sex hormones on general immune function. The contributors examine the role of sex hormones in the immune response against various parasitic infections in both mice and humans, as well as nonendocrine autoimmune diseases. They then proceed to examine the various roles of sex hormones on the different aspects of immunity. They manage to make this an informative and interesting topic.
Assessment: I found this text an extremely useful and interesting source. Although the editor doubts that he will edit any similar texts in the future, I hope that this will prove untrue. With the rapidly expanding knowledge base in both fields, I have no doubt that a new text will soon be required.
This book would serve as an excellent reference for researchers, students, and fellows, as well as clinicians who desire a deeper appreciation for the pathogenesis of many of the diseases in the patients they treat. . .an extremely useful and interesting source."Doody's Health Science Book Review Journal
"The authors of this text are some of the world leaders in the field. . .this book provides an excellent overview of current knowledge on the subject of autoimmune endocrine diseases,, and as such is of great interest to the endocrinologist with an interest in immunology, and indeed to the immunologist with an interest in endocrinology. I recommend it highly."-The Endocrinologist
"The book is well referenced and contains many helpful tables and figures. It is of interest to all endocrinologists, immunologists, and diabetologists."-Journal of Pediatric Endocrinology & Metabolism
