Baculovirus Expression Systems and Biopesticides / Edition 1

by Michael L. Shuler, H. Alan Wood, Robert R. Granados, Daniel A. Hammer

Overview

Baculovirus Expression Systems and Biopesticides Edited by MichaelL. Shuler, H. Alan Wood, Robert R. Granados, and Daniel A. HammerBaculovirus Expression Systems and Biopesticides provides anintegrated perspective on the use of the continually evolvingbaculovirus-insect cell system in the production of recombinantproteins and genetically engineered pesticides. Divided into threemain sections—Developing Effective Virus-Insect Culture Systems,Bioreactor Design and Scale-Up Issues, and Commercial Applicationof Insect Cell Culture—the book, written by highly regardededitors in the field, describes:
* The molecular biology and genetics of baculoviruses
* The use of baculoviruses as expression systems
* Principles and methods for small- and large-scale insectcultures
* The use of wild type and genetically engineered baculoviruses asviral pesticides
The breadth of coverage in Baculovirus Expression Systems andBiopesticides will meet the needs of molecular biologists, chemicalengineers, biotechnologists,virologists, and entomologists.

Product Details

ISBN-13:	9780471065807
Publisher:	Wiley
Publication date:	12/13/1994
Pages:	259
Product dimensions:	6.42(w) x 9.57(h) x 0.83(d)

About the Author

MICHAEL L. SHULER is Professor of Chemical Engineering with a joint appointment in the Institute of Food Science at Cornell University.

Table of Contents

Partial table of contents:

DEVELOPING EFFECTIVE BACULOVIRUS-INSECT CULTURE SYSTEMS.

Insect Cell Culture Methods and Their Use in Virus Research (R.Granados & K. McKenna).

Comparison of Mammalian and Insect Cell Cultures (M. Shuler).

Development and Testing of Genetically Improved BaculovirusInsecticides (H. Wood).

BIOREACTOR DESIGN AND SCALE-UP ISSUES.

Overview of Issues in Bioreactor Design and Scale-Up (R. Taticek,et al.).

The Effect of Hydrodynamic Forces on Insect Cells (J.Chalmers).

COMMERCIAL APPLICATION OF INSECT CELL CULTURE.

Baculovirus-Mediated Production of Proteins in Insect Cells:Examples of Scale-Up and Product Recovery (M. Silberklang, etal.).

Index.

Editorial Reviews

Reviewer: Ruiyin Chu, PhD (Northwestern University Feinberg School of Medicine)
Description: This book describes the current advances and remaining obstacles associated with the commercial development of baculovirus expression systems as well as the production of viral pesticides.
Purpose: The topics are diverse yet interrelated and focus on the transcriptional, translational, and post-translational regulatory factors governing foreign gene expression and virus replication. It aims to provide a multidimensiunal view on the interplay between viral, cellular, and extracellular factors. It is an essential book for professionals and students.
Audience: This book is primarily targeted toward students and postdoctorate fellows to aid them with a complete, thorough understanding of the baculovirus expression system and the use of baculovirus as a biopesticide.
Features: Tables, graphs, charts, and pictures are illustrated appropriately. References span a wide range and include the most current ones as well. The contents and index are adequate. The overall appearance of the book is simple but sufficient.
Assessment: It is a very useful reference textbook for students, postdoctorate fellows, and principal investigators of laboratories. Some of the information is novel and is compiled together rather ingeniously.

Doody's Review Service

3 Stars from Doody

This book describes the current advances and remaining obstacles associated with the commercial development of baculovirus expression systems as well as the production of viral pesticides. The topics are diverse yet interrelated and focus on the transcriptional, translational, and post-translational regulatory factors governing foreign gene expression and virus replication. It aims to provide a multidimensiunal view on the interplay between viral, cellular, and extracellular factors. It is an essential book for professionals and students. This book is primarily targeted toward students and postdoctorate fellows to aid them with a complete, thorough understanding of the baculovirus expression system and the use of baculovirus as a biopesticide. Tables, graphs, charts, and pictures are illustrated appropriately. References span a wide range and include the most current ones as well. The contents and index are adequate. The overall appearance of the book is simple but sufficient. It is a very useful reference textbook for students, postdoctorate fellows, and principal investigators of laboratories. Some of the information is novel and is compiled together rather ingeniously.

Ruiyin Chu

Provides an integrated perspective on the use of the continually evolving baculovirus-insect cell system in the production of recombinant proteins and genetically engineered pesticides. Explains the development of effective virus-insect culture systems, bioreactor design and scale-up issues, and the commercial application of insect cell culture. Of interest to molecular biologists, biotechnologists, virologists, and entomologists. Annotation c. Book News, Inc., Portland, OR (booknews.com)

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