Biotechnology: The Technological Applications of Genetics and Genomics

by David P. Clark, Nanette J. Pazdernik, Michelle R. McGehee, Bethany A. Rader

Overview

Biotechnology: The Technological Applications of Genetics and Genomics, Third Edition, approaches modern biotechnology from a molecular basis, discussing how the fields of genetics, molecular biology, microbiology, and biochemistry are merging their respective discoveries into the expanding applied field of biotechnology. Each chapter starts with basic concepts that develop into more specific and detailed applications, providing readers with a good image of possibilities and current limitations in the field and future research directions. This new edition has been fully revised and updated to include research advances, and has new chapters on artificial intelligence, genome editing, precision and personalized medicine, and more. This book is an invaluable resource to anyone interested in understanding what molecular biotechnology is as a scientific discipline, how research in this area is conducted, and how this technology may impact the future.

Product Details

ISBN-13:	9780443184840
Publisher:	Elsevier Science
Publication date:	01/31/2025
Pages:	900
Product dimensions:	8.50(w) x 10.88(h) x (d)

About the Author

David P. Clark did his graduate work on bacterial antibiotic resistance to earn his Ph.D. from Bristol University, England. He later crossed the Atlantic to work as a postdoctoral researcher at Yale University and then the University of Illinois. Dr Clark recently retired from teaching Molecular Biology and Bacterial Physiology at Southern Illinois University which he joined in 1981. His research into the Regulation of Alcohol Fermentation in E. coli was funded by the U.S. Department of Energy, from 1982 till 2007. In 1991 he received a Royal Society Guest Research Fellowship to work at Sheffield University, England while on sabbatical leave.

Nanette J. Pazdernik has devoted her career to the understanding of molecular biology and biotechnology, and then disseminating that knowledge by writing and teaching. She is a co-author of Biotechnology, 2nd edition and Molecular Biology, 3rd edition, with Dr. David P. Clark and Dr. Michelle McGehee. Both the second and third edition of Molecular Biology won a Texty award from the Textbook and Academic Authors Association. She has taught courses in General Biology, Genetics, as well as Anatomy and Physiology at Southwestern Illinois College, McKendree University, and Harris-Stowe University. She received her BA in Biology from Lawrence University in Appleton, Wisconsin, and her PhD in Molecular, Cellular, Developmental Biology and Genetics from the University of Minnesota. Her doctoral thesis studied protein structure-function relationships. Following her degrees, she investigated the signal transduction pathways that control apoptosis and immunity at Indiana University School of Medicine. In a second post-doctoral position, she studied the various molecules that maintain the stem cell niche in the Department of Genetics at Washington University School of Medicine in St. Louis, MO. Currently, Dr. Pazdernik works in the biotech industry as a scientific writer.

Michelle R. McGehee earned a BA in Microbiology in 2000 and a PhD in Molecular Biology, Microbiology, and Biochemistry in 2005, both from Southern Illinois University in Carbondale, USA. Her graduate research focused on the genetic and biochemical regulation of lactate fermentation in Escherichia coli. Michelle is currently an assistant academic dean and biology professor at a college in Texas, where she teaches courses in both microbiology and genetics.

Bethany A. Rader received a BS in Botany from the University of Wisconsin in 1999, and a PhD in Biology from the University of Oregon in 2006. Her current research explores mechanisms of host tolerance to beneficial bacterial symbionts and the potentially harmful molecules they produce. She continues her research as an associate professor at Southern Illinois University in the Microbiology Program where she has mentored undergraduate, Masters, and PhD students.

Table of Contents

1. Basics of biotechnology 2. DNA, RNA, and protein 3. Recombinant DNA technology 4. DNA synthesis and PCR 5. RNA-based technologies 6. Immune technology 7. Genomics and sequencing 8. Transcriptomics 9. Bioinformatics 10. Proteomics 11. Recombinant proteins 12. Protein engineering 13. Synthetic biology 14. Nanobiotechnology 15. Bio-robotics to Artificial Intelligence 16. Environmental biotechnology 17. Plant biotechnology 18. Transgenic animals 19. Inherited defects and gene therapy 20. Genome Editing 21. Stem cells & applications 22. Cancer 23. Precision medicine 24. Viral and prion infections 25. Biowarfare and bioterrorism 26. Emerging Infections 27. Bioethics in biotechnology

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From the Publisher

A comprehensive overview of modern biotechnology from a molecular basis integrating basic science and concise applications