Bone Marrow and Stem Cell Transplantation / Edition 1

by Meral Beksaç

Overview

Molecular Methods: Stem Cell Transplantation presents a compendium of cutting-edge research on the molecular steps involved in hematopoietic stem cell (HSC) activation and self-renewal. The emergence of HLA typing, and the positive impact it has had on the success of clinical transplantation is emphasized and discussed by notable stem cell researchers.

Product Details

ISBN-13:	9781588295958
Publisher:	Springer-Verlag New York, LLC
Publication date:	05/03/2007
Series:	Methods in Molecular Medicine , #134
Edition description:	2007
Pages:	234
Product dimensions:	5.98(w) x 9.02(h) x 0.03(d)

Table of Contents

Molecular Profiling of Hematopoietic Stem Cells.- Methods for Imaging Cell Fates in Hematopoiesis.- An Overview of HLA Typing for Hematopoietic Stem Cell Transplantation.- Sequence-Specific Primed PCR (PCR-SSP) Typing of HLA Class I and Class II Alleles.- HLA Typing with Sequence-Specific Oligonucleotide Primed PCR (PCR-SSO) and Use of the Luminex™ Technology.- Sequencing-Based Typing of HLA.- Molecular Typing Methods for Minor Hisompatibility Antigens.- Non-HLA Gene Polymorphisms in Stem Cell Transplantation.- Polymorphisms Within Epithelial Receptors.- Role of Natural Killer Cells and Killer Immunoglobulin-Like Receptor Polymorphisms.- Identification of Bone Marrow Derived Nonhematopoietic Cells by Double Labeling with Immunohishemistry and In Situ Hybridization.- Molecular Methods Used for Detection of Minimal Residual Disease Following Hematopoietic Stem Cell Transplantation in Myeloid Disorders.- Molecular Methods Used for The Detection of Autologous Graft Contamination in Lymphoid Disorders.- Detection of Impending Graft Rejection and Relapse by Lineage-Specific Chimerism Analysis.- Application of Proteomics to Posttransplantational Follow-Up.