BRS Pathology / Edition 6

by Mary Elizabeth Peyton Gupta MD

Overview

This powerful, easy-to-use resource presents the essentials of pathology in the popular Board Review Series outline format that highlights the most tested topics for the USMLE Step 1. Packed with new content; high-yield topics; concise descriptions; more than 450 USMLE-style questions with complete answers and explanations; and full-color illustrations, photomicrographs, and radiologic images, BRS Pathology, Sixth Edition, provides everything needed for course success and board exam prep.

• An easy-to-scan outline format with bolded key terms and summary tables enables concise review and exam preparation.
• Chapter-ending exams focus on high-yield, clinical content.
• An end-of-book Comprehensive Exam helps students gauge their mastery of key topics.
• New cross-references in the answers to the Comprehensive Exam use an outline format (section number/letter) to facilitate efficient study and easy linking in all formats.
• Many new full-color photomicrographsand schematic illustration provide visual learning and review.
• Key topic icons help students quickly locate important content.
• An online interactive question bank features all the questions from the book for anytime, anywhere test preparation and review.
• eBook available for purchase. Fast, smart, and convenient, today’s eBooks can transform learning. These interactive, fully searchable tools offer 24/7 access on multiple devices, the ability to highlight and share notes, and more

Product Details

ISBN-13:	9781975136628
Publisher:	LWW
Publication date:	04/22/2020
Series:	Board Review Series
Edition description:	Sixth, North American Edition
Pages:	496
Product dimensions:	7.00(w) x 10.00(h) x (d)

Table of Contents

Preface vi

Acknowledgments vii

1 Cellular Reaction to Injury 1

I Adaptation to Environmental Stress 1

II Hypoxic Cell Injury 3

III Free Radical Injury 4

IV Chemical Cell Injury 4

V Necrosis 5

VI Apoptosis 7

VII Reversible Cellular Changes and Accumulations 8

VIII Disorders Characterized by Abnormalities of Protein Folding 12

IX Cellular Aging 12

Review Test 13

2 Inflammation 18

I Introduction 18

II Acute Inflammation 18

III Chronic Inflammation 25

IV Tissue Repair 27

Review Test 29

3 Hemodynamic Dysfunction 33

I Hemorrhage 33

II Hyperemia 33

III Infarction 34

IV Thrombosis 34

V Embolism 39

VI Edema 41

VII Shock 42

Review Test 44

4 Genetic Disorders 49

I Chromosomal Disorders 49

II Modes of Inheritance of Monogenic Disorders 53

III Examples of Mendelian Disorders 54

IV Balanced Polymorphism 60

V Polygenic and Multifactorial Disorders 61

VI Disorders of Sexual Differentiation 61

Review Test 62

5 Immune Dysfunction 66

I Cells of the Immune System 66

II Cytokines 67

III Complement System 67

IV Human Leukocyte Antigen System 68

V Innate Versus Acquired Immunity 68

VI Mechanisms of Immune Injury 69

VII Transplantation Immunology 71

VIII Immunodeficiency Diseases 72

IX Autoimmunity 76

X Connective Tissue (Collagen) Diseases 77

XI Amyloidosis 79

Review Test 82

6 Neoplasia 87

I General Considerations 87

II Classification and Nomenclature of Tumors 87

III Properties of Neoplasms 89

IV Carcinogenesis and Etiology 93

V Other Neoplastic Disorders with Known DNA Defects 97

VI Grading and Staging 98

Review Test 99

7 Environmental Pathology 103

I Physical Injury 103

II Chemical Abuse 105

III Environmental Chemical Injuries 107

IV Adverse Effects of Therapeutic Drugs 108

Review Test 110

8 Nutritional Disorders 114

I Malnutrition 114

II Vitamins 114

III Obesity 118

IV Cancer 118

Review Test 119

9 Vascular System 123

I Arterial Disorders 123

II Venous Disorders 127

III Tumors of Blood Vessels 128

IV Vasculitis Syndromes (Vasculitides) 129

V Functional Vascular Disorders 131

VI Hypertension 131

Review Test 134

10 The Heart 139

I Ischemic Heart Disease (IHD) 139

II Rheumatic Fever 141

III Other Forms of Endocarditis 143

IV Valvular Heart Disease 144

V Congenital Heart Disease 146

VI Diseases of the Myocardium 147

VII Diseases of the Pericardium 148

VIII Tumors of the Heart 149

IX Congestive Heart Failure 149

X Hypertrophy of the Heart 150

Review Test 152

11 Anemia 158

I General Concepts 158

II Acute Posthemorrhagic Anemia 158

III Iron Deficiency Anemia 159

IV Megaloblastic Anemias 160

V Anemia of Chronic Disease 162

VI Aplastic Anemia 162

VII Myelophthisic Anemia 163

VIII Hemolytic Anemias 163

Review Test 170

12 Neoplastic and Proliferative Disorders of the Hematopoietic and Lymphoid Systems 175

I Leukemia 175

II Myeloproliferative Diseases 178

III Non-Neoplastic Lymphoid Proliferations 179

IV Plasma Cell Disorders 180

V Lymphoid Neoplasms 182

Review Test 189

13 Hemorrhagic Disorders 195

I Disorders of Primary Hemostasis 195

II Disorders of Secondary Hemostasis 197

III Combined Primary and Secondary Hemostatic Defects 199

Review Test 200

14 Respiratory System 204

I Disorders of the Upper Respiratory Tract 204

II Tumors of the Upper Respiratory Tract 204

III Chronic Obstructive Pulmonary Disease 205

IV Restrictive Pulmonary Disease 208

V Pulmonary Vascular Disease 214

VI Pulmonary Infection 215

VII Miscellaneous Disorders of the Lungs 218

VIII Cancers of the Lung 219

Review Test 222

15 Gastrointestinal Tract 228

I Diseases of the Mouth and Jaw 228

II Diseases of the Salivary Glands 229

III Diseases of the Esophagus 230

IV Diseases of the Stomach 232

V Diseases of the Small Intestine 235

VI Diseases of the Colon 237

VII Diseases of the Appendix 243

Review Test 244

16 Liver, Gallbladder, and Exocrine Pancreas 250

I Diseases of the Liver 250

II Diseases of the Gallbladder 258

III Diseases of the Exocrine Pancreas 259

Review Test 261

17 Kidney and Urinary Tract 267

I Congenital Anomalies of the Urinary Tract 267

II Glomerular Diseases 267

HI. Urinary Tract Obstruction 272

IV Infection of the Urinary Tract and Kidney 273

V Tubular and Interstitial Disorders of the Kidney 273

VI Diffuse Cortical Necrosis 275

VII Nephrocalcinosis 275

VIII Urolithiasis 276

IX Cystic Diseases of the Kidney 276

X Renal Failure 277

XI Nonrenal Causes of Azotemia 277

XII Tumors of the Kidney, Urinary Tract, and Bladder 278

Review Test 281

18 Male Reproductive System 290

I Diseases of the Penis 290

II Diseases of the Testes 291

III Diseases of the Prostate 294

Review Test 296

19 Female Reproductive System and Breast 300

I Vulva and Vagina 300

II Uterine Cervix 303

III Uterine Corpus 304

IV Fallopian Tubes 307

V Ovaries 307

VI Disorders of Pregnancy 310

VII Breast 313

Review lest 316

20 Endocrine System 323

I Pituitary 323

II Thyroid Gland 325

III Parathyroid Glands 329

IV Adrenal Glands 331

V Endocrine Pancreas 334

VI Multiple Endocrine Neoplasia (MEN) Syndromes 337

Review Test 338

21 Skin 347

I Terminology Relating to Skin Diseases 347

II Inflammatory and Vesicular Lesions 347

III Disorders of Pigmentation 349

IV Disorders of Viral Origin 350

V Miscellaneous Skin Disorders 350

VI Skin Malignancies 352

Review Test 354

22 Musculoskeletal System 357

I Diseases of Skeletal Muscle 357

II Diseases of Bone 359

III Diseases of Joints 365

IV Soft-Tissue Tumors 368

Review Test 370

23 Nervous System 374

I Congenital Disorders 374

II Cerebrovascular Disease 375

III Head Injuries 376

IV Infections 377

V Demyelinating Diseases 381

VI Degenerative Diseases 382

VII Tumors 385

VIII Ocular Disorders 388

Review Test 390

24 Interpretation of Diagnostic Tests: Laboratory Statistics 395

I General Considerations 395

II Sensitivity and Specificity 395

III Positive and Negative Predictive Values 396

IV Variation 397

V Standard deviation 397

Review Test 398

Comprehensive Examination 402

Index 436

Editorial Reviews

Reviewer: Anamarija Perry, MD (University of Michigan Medical School)
Description: This is the sixth updated edition of the pathology volume in the Board Review Series. The previous edition was published in 2014.
Purpose: The purpose of this text is to serve as a review material for questions encountered on the USMLE and other similar examinations.
Audience: This book is intended primarily for medical students who are preparing for board exams.
Features: The book is organized to parallel content of major pathology textbooks and includes eight chapters covering general pathology, followed by 15 chapters covering the pathology of the organ system. A final chapter is dedicated to statistical concepts of laboratory medicine. The chapters are well written and cover high-yield concepts and diseases frequently tested on the board exam. So called "key associations" that serve as the basis for many examination questions are marked throughout the text with a symbol resembling a key. The book contains a good number of gross and microscopic images that are an important tool to illustrate disease mechanisms. A number of useful tables and figures also complement the text. Each chapter ends with a set of review questions and a comprehensive examination is included at the end of the book. All questions are written in a form of clinical vignettes. Moreover, a section of answers and explanations follows the questions where important teaching points are emphasized.
Assessment: As stated in the preface, this book is best used not as a primary text, but as a supplement for study and review. As such, it is a great resource for medical students as it provides a relatively quick review of the most important concepts in pathology. One of the best features of the book is the review questions that successfully emulate the actual USMLE board exam. Unfortunately, a significant number of gross and microscopic images are dark or suboptimally white-balanced, which could be improved in the next edition. In summary, I would highly recommend this book to all medical students.

Doody's Review Service