Table of Contents
Contributors vii
Preface to the Fourth Edition ix
1 How it all began: cancer cytogenetics before sequencing 1Felix Mitelman and Sverre Heim
2 Cytogenetic methods 11David Gisselsson
3 Cytogenetic nomenclature 19Sverre Heim and Felix Mitelman
4 Nonrandom chromosome abnormalities in cancer: an overview 26Sverre Heim and Felix Mitelman
5 From chromosomes to genes: searching for pathogenetic fusions in cancer 42Ioannis Panagopoulos
6 Acute myeloid leukemia 62Bertil Johansson and Christine J. Harrison
7 Myelodysplastic syndromes 126Harold J. Olney and Michelle M. Le Beau
8 Chronic myeloid leukemia 153Thoas Fioretos
9 Chronic myeloproliferative neoplasms 175Peter Vandenberghe and Lucienne Michaux
10 Acute lymphoblastic leukemia 198Christine J. Harrison and Bertil Johansson
11 Mature B?] and T-cell neoplasms and Hodgkin lymphoma 252Reiner Siebert and Sietse M. Aukema
12 Tumors of the upper aerodigestive tract 332Susanne M. Gollin
13 Tumors of the lung 361Penny Nymark, Eeva Kettunen and Sakari Knuutila
14 Tumors of the digestive tract 373Georgia Bardi and Sverre Heim
15 Tumors of the urinary tract 401Paola Dal Cin
16 Tumors of the breast 426Manuel R. Teixeira, Nikos Pandis and Sverre Heim
17 Tumors of the female genital organs 447Francesca Micci and Sverre Heim
18 Tumors of the male genital organs 481Manuel R. Teixeira and Sverre Heim
19 Tumors of endocrine glands 497Jörn Bullerdiek and David Gisselsson
20 Tumors of the nervous system 515Petter Brandal and Sverre Heim
21 Tumors of the eye 538Karen Sisley
22 Tumors of the skin 555Fredrik Mertens, Felix Mitelman and Sverre Heim
23 Tumors of bone 566Fredrik Mertens and Nils Mandahl
24 Soft tissue tumors 583Nils Mandahl and Fredrik Mertens
Index 615