Cardiovascular Physiology 8/E

by David E. Mohrman, Lois Jane Heller

Overview

The best cardiovascular physiology text for USMLE and exam review

Cardiovascular Physiology is a concise and enjoyable way for you to gain a fundamental knowledge of the basic operating principles of the intact cardiovascular system and how those principles apply to clinical medicine. Succinct but thorough, it focuses on the facts and concepts you must know to get a solid "big picture" overview of how the cardiovascular system operates in normal and abnormal situations. No other text will prove more valuable in enhancing your ability to evaluate the myriad new information you will be exposed to throughout your career, than Cardiovascular Physiology.

FEATURES

• NEW Includes a "Perspectives" section in each chapter that identifies important unresolved issues
• Clarifies the details of physiologic mechanisms and their role in pathologic states
• Links cardiovascular physiology to diagnosis and treatment
• Summarizes key concepts at the end of each chapter
• Highlights must-know information with chapter objectives
• Reinforces learning with study questions at the end of each chapter

Product Details

ISBN-13:	9780071793124
Publisher:	McGraw Hill LLC
Publication date:	02/05/2014
Sold by:	Barnes & Noble
Format:	eBook
Pages:	304
File size:	6 MB

About the Author

Associate Professor, Department of Medical and Molecular Physiology, School of Medicine, University of Minnesota, Duluth

Professor, Department of Medical and Molecular Physiology, School of Medicine, University of Minnesota, Duluth

Table of Contents

Preface ix

Chapter 1 Overview of the Cardiovascular System 1

Objectives 1

Homeostatic Role of the Cardiovascular System 2

The Basic Physics of Blood Flow 6

Material Transport by Blood Flow 8

The Heart 9

The Vasculature 15

Blood 17

Perspectives 19

Key Concepts 19

Study Questions 20

Chapter 2 Characteristics of Cardiac Muscle Cells 22

Objectives 22

Electrical Activity of Cardiac Muscle Cells 23

Mechanical Activity of the Heart 38

Relating Cardiac Muscle Cell Mechanics to Ventricular Function 48

Perspectives 49

Key Concepts 49

Study Questions 50

Chapter 3 The Heart Pump 52

Objectives 52

Cardiac Cycle 53

Determinants of Cardiac Output 60

Influences on Stroke Volume 60

Summary of Determinants of Cardiac Output 64

Cardiac Energetics 68

Perspectives 70

Key Concepts 70

Study Questions 71

Chapter 4 Measurements of Cardiac Function 73

Objectives 73

Measurement of Mechanical Function 73

Measurement of Cardiac Excitation-The Electrocardiogram 77

Perspectives 87

Key Concepts 87

Study Questions 88

Chapter 5 Cardiac Abnormalities 90

Objectives 90

Electrical Abnormalities and Arrhythmias 90

Cardiac Valve Abnormalities 95

Perspectives 98

Key Concepts 99

Study Questions 100

Chapter 6 The Peripheral Vascular System 102

Objectives 102

Transcapillary Transport 104

Resistance and Flow in Networks of Vessels 109

Normal Conditions in the Peripheral Vasculature 112

Measurement of Arterial Pressure 118

Determinants of Arterial Pressure 119

Perspectives 122

Key Concepts 122

Study Questions 124

Chapter 7 Vascular Control 126

Objectives 126

Vascular Smooth Muscle 127

Control of Arteriolar Tone 132

Control of Venous Tone 141

Summary of Primary Vascular Control Mechanisms 142

Vascular Control in Specific Organs 143

Perspectives 154

Key Concepts 154

Study Questions 155

Chapter 8 Hemodynamic Interactions 157

Objectives 157

Key System Components 158

Central Venous Pressure: An Indicator of Circulatory Status 160

Perspectives 170

Key Concepts 170

Study Questions 171

Chapter 9 Regulation of Arterial Pressure 172

Objectives 172

Short-Term Regulation of Arterial Pressure 173

Long-Term Regulation of Arterial Pressure 183

Perspectives 189

Key Concepts 190

Study Questions 191

Chapter 10 Cardiovascular Responses to Physiological Stresses 193

Objectives 193

Primary Disturbances and Compensatory Responses 195

Effect of Respiratory Activity 195

Effect of Gravity 198

Effect of Exercise 203

Normal Cardiovascular Adaptations 208

Perspectives 212

Key Concepts 213

Study Questions 214

Chapter 11 Cardiovascular Function in Pathological Situations 216

Objectives 216

Circulatory Shock 217

Cardiac Disturbances 222

Hypertension 231

Perspectives 235

Key Concepts 235

Study Questions 236

Answers to Study Questions 238

Appendix A 256

Appendix B 257

Appendix C 258

Appendix D 259

Appendix E 262

Index 267