Cellular and Molecular Immunology E-Book: Cellular and Molecular Immunology E-Book

by Abul K. Abbas MBBS, PhD Lichtman MD, PhD Pillai MD

Overview

Popular for its highly visual, straightforward approach, Cellular and Molecular Immunology delivers an accessible yet thorough understanding of this active and fast-changing field. Drs. Abul K. Abbas, Andrew H. Lichtman, and Shiv Pillai present key updates in this new edition to cover the latest developments in antigen receptors and signal transduction in immune cells, mucosal and skin immunity, cytokines, leukocyte-endothelial interaction, and more. With additional online features, this is an ideal resource for medical, graduate and undergraduate students of immunology who need a clear, introductory text for immunology courses. - Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. - Develop a thorough, clinically relevant understanding of immunology through a clear overview of immunology with a distinct focus on the management of human disease. - Visualize immunologic processes more effectively. Meticulously developed and updated illustrations, 3-dimensional art, and all-new animations provide a detailed, visual description of the key immunologic and molecular processes. - Grasp the details of experimental observations that form the basis for the science of immunology at the molecular, cellular, and whole-organism levels and draw the appropriate conclusions. - Find information more quickly and easily through an organized chapter structure and a more logical flow of material. - Glean all essential, up-to-date, need-to-know information about immunology and molecular biology through extensive updates that cover cytokines, innate immunity, leukocyte-endothelial interactions, signaling, costimulation, and more. - Benefit from numerous new figures and tables that facilitate easier retention of the material; quick summaries of each chapter; and nearly 400 illustrations that clarify key concepts.

Product Details

ISBN-13:	9780323286459
Publisher:	Saunders, W. B. Company
Publication date:	08/15/2014
Sold by:	Barnes & Noble
Format:	eBook
Pages:	544
File size:	59 MB
Note:	This product may take a few minutes to download.

About the Author

Abul K. Abbas, MBBS, Distinguished Professor and Chair, Department of Pathology, University of California San Francisco, San Francisco, California

Table of Contents

1. Properties and Overview of Immune Responses, 1 2. Cells and Tissues of the Immune System, 13 3. Leukocyte Circulation and Migration into Tissues, 35 4. Innate Immunity, 51 5. Antibodies and Antigens, 87 6. Major Histocompatibility Complex Molecules and Antigen Presentation to T Lymphocytes, 107 7. Immune Receptors and Signal Transduction, 137 8. Lymphocyte Development and Antigen Receptor Gene Rearrangement, 171 9. Activation of T Lymphocytes, 199 10. Differentiation and Functions of CD4+ Effector T Cells, 213 11. Differentiation and Functions of CD8+ Effector T Cells, 231 12. B Cell Activation and Antibody Production, 239 13. Effector Mechanisms of Humoral Immunity, 265 14. Specialized Immunity at Epithelial Barriers and in Immune Privileged Tissues, 289 15. Immunologic Tolerance and Autoimmunity, 315 16. Immunity to Microbes, 339 17. Transplantation Immunology, 359 18. Immunity to Tumors, 383 19. Hypersensitivity Disorders, 399 20. Allergy, 417 21. Congenital and Aquired Immunodeficiencies, 437 Appendix I. Glossary, 465 Appendix II. Cytokines, 493 Appendix III. Principle Features of Selected CD Molecules, 497 Appendix IV. Laboratory Techniques Commonly Used in Immunology, 503 Index, 517

Editorial Reviews

4 Stars! from Doody

"A book that is now in its 8th edition is obviously one that has been found to be useful by students and instructors. This is one of the more popular choices among immunology books. For some students, it might provide more information than they need, but that depends entirely on the level of the course. In any event, it would surely be an excellent resource. Given the rapid changes in what we know about immunology, the need for this new edition should be obvious."

- Marion C. Cohen, PhD (SUNY Downstate Medical Center) Doody’s Score: 91 - 4 Stars!

From the Publisher

Reviewer: Marion C. Cohen, PhD (SUNY Downstate Medical Center)
Description: This is the fifth edition of a popular textbook on basic immunology. It has been updated so that it incorporates new scientific information that has been published and accepted by the immunological community since the previous edition, published in 2000.
Purpose: The purpose is to give students an explanation of the experimental observations that form the basis for immunology at the molecular, cellular, and whole organism levels. It further explains how the immune system is involved in human disease thus providing the student with a clinical context for the material. For the medical or dental student faced with finding contextual significance for the large amount of basic science material that s/he is required to absorb, the book provides a guide through the sometimes difficult language and concepts of immunology. While there are a large number of immunology textbooks on the market, this book is one in which a student will find explanations for most questions about immunological concepts that s/he might have.
Audience: The book is targeted to medical, dental, and graduate students taking an immunology course that includes both the essential components of the immune system and how they function in immune responses, as well as the immune system in disease. It is useful as a source of information for anyone at any level of competence. The authors are well known and highly respected immunologists.
Features: The book covers all those topics that are usually discussed in any standard immunology course. Although the chapter headings are the same as those in the fourth edition, there are substantial changes. Information in some areas has expanded enormously and is reflected in new material on topics relating to innate immunity and signal transduction. Some new figures have been added and others have been modified so that they are easier to understand. Some of the colors are more intense than in the fourth edition. Tables have been redesigned so that they are much easier to read. As in the past, "boxes" have been used to present information about experimental approaches, diseases, and some specific molecular or biological processes. Taken together, all of these changes have improved what was already a user-friendly and very readable textbook. As before, there are three appendixes: a glossary; principal features of CD molecules; and laboratory techniques. Most basic courses will include some information from each chapter in the book, although the level of detail required will certainly vary. There are still some idiosyncratic features. For example, Type II hypersensitivity reactions now precede Type III and Type IV hypersensitivity reactions with autoimmunity (often a separate chapter) at the end. However, as in the previous edition, this is followed by Type I hypersensitivity as a separate chapter. There is probably a rationale for this untraditional order but it isn't obvious. Other textbooks have included case studies that provide relevance, particularly with respect to basic concepts. Unfortunately this book does not have this kind of reinforcement. On the other hand, the summary at the end of each chapter focuses the attention of the student towards the importance of the material just presented.
Assessment: Immunology is a constantly changing field so there is a need for frequent revisions so that textbooks remain current and accurate. Thus there is a good rationale for publishing this new edition. The fourth edition was an attractive book and the fifth is even more attractive with clearer figures and tables. The book is easy to read and while it is targeted to students, it could serve as a reference for anyone who needs some background information on basic immunology as well as immune-mediated diseases. There are a number of immunology textbooks currently on the market. Although some of the others may have some features that are useful, as an all-purpose book for teaching medical, dental, and graduate students, this book is certainly one of the best.

Doody's Review Service