Chromatographic Processes: Modeling, Simulation, and Design

by Roger-Marc Nicoud

Overview

Addressing all aspects of the design, modeling and simulation of chromatographic processes, this result-oriented primer provides a practical guide to all the necessary approaches, methodologies and tools. Beginning with key definitions and concepts, it builds up from the most simple to the most complex situations, including multicomponent systems, non-uniform velocity profiles, bed instability, particle size distributions, and the influence of complex environments on chromatographic process design. In addition to covering classical approaches, it introduces efficient tools for investigating chromatographic processes, such as the 'Russian-Lego' approach for linear systems, phenomenological models, and specific shortcuts for deriving the key properties of industrial processes. With an emphasis on real-world problems and applications, step-by step modeling design guidelines, and detailed exercises for self-assessment, this is a must-have guide for practitioners and researchers working in chemical, biochemical, food and pharmaceutical engineering.

Product Details

ISBN-13:	9781107082366
Publisher:	Cambridge University Press
Publication date:	04/20/2015
Series:	Cambridge Series in Chemical Engineering
Pages:	672
Product dimensions:	7.17(w) x 10.00(h) x 1.34(d)

About the Author

Roger-Marc Nicoud is the founder and former CEO of Novasep, which has installed over 2000 chromatographic units worldwide, and pioneered the use of large-scale continuous chromatographic processes in the life science industry. He is President of École Nationale Supérieure des Industries Chimiques (ENSIC), and in 2014, founded Ypso-Facto (www.ypsofacto.com).

Table of Contents

1. An approach to modeling chromatographic processes; 2. Linear chromatography: the Russian Lego; 3. Non-linear chromatography: equilibrium theory; 4. Fluid-solid phase equilibria; 5. Mass transfer; 6. Hydrodynamics of chromatographic columns; 7. Simulating chromatographic columns; 8. Counter-current systems; 9. Presentation of chromatographic modes and their optimization; 10. Addressing a few industrial problems; 11. Conclusion.