Clinical Virology

by Douglas D. Richman (Editor), Richard J. Whitley (Editor), Frederick G. Hayden (Editor)

Overview

The essential reference of clinical virology

Virology is one of the most dynamic and rapidly changing fields of clinical medicine. For example, sequencing techniques from human specimens have identified numerous new members of several virus families, including new polyomaviruses, orthomyxoviruses, and bunyaviruses.

Clinical Virology, Fourth Edition, has been extensively revised and updated to incorporate the latest developments and relevant research. Chapters written by internationally recognized experts cover novel viruses, pathogenesis, epidemiology, diagnosis, treatment, and prevention, organized into two major sections:

• Section 1 provides information regarding broad topics in virology, including immune responses, vaccinology, laboratory diagnosis, principles of antiviral therapy, and detailed considerations of important organ system manifestations and syndromes caused by viral infections.
• Section 2 provides overviews of specific etiologic agents and discusses their biology, epidemiology, pathogenesis of disease causation, clinical manifestations, laboratory diagnosis, and management.

Clinical Virology provides the critical information scientists and health care professionals require about all aspects of this rapidly evolving field.

Product Details

ISBN-13:	9781683673163
Publisher:	Wiley
Publication date:	12/01/2016
Series:	ASM Books
Sold by:	JOHN WILEY & SONS
Format:	eBook
File size:	254 MB
Note:	This product may take a few minutes to download.

About the Author

Richman, Douglas D., MD (UCSD); Whitley, Richard J., MD (Univ of Alabama); Hayden, Frederick G., MD (Univ of Virginia)

The contributors represent the specialties of virology, immunology, microbiology, infectious disease, internal medicine, and pathology. Most are from hospitals, universities, and research centers in nine countries, including the U.S., the U.K., Australia, and Italy. Institutions prominently represented include National Institute of Allergy and Infectious Diseases, CDC, Baylor, Columbia, Univ of Virginia, and Univ of Alabama-Birmingham.

Table of Contents

CHAPTER 1 Introduction (Pages: 1-5)
Douglas D. Richman, Richard J. Whitley, Frederick J. Hayden

Section I : Viral Syndromes and General Principles

CHAPTER 2 Respiratory Infections (Pages: 7-29)
John J. Treanor

CHAPTER 3 Viral Infections of the Central Nervous System (Pages: 31-45)
Kevin A Cassady, Richard J. Whitley

CHAPTER 4 Gastrointestinal Syndromes (Pages: 47-59)
Eyal Leshem, Umesh D. Parashar

CHAPTER 5 Viral Hepatitis (Pages: 61-73)
Zina S. Valaydon, Stephen A. Locarnini, Alexander J.V. Thompson

CHAPTER 6 Viral Infections in Organ Transplant Recipients (Pages: 75-98)
John A. Zaia

CHAPTER 7 Viral Heart Disease (Pages: 99-113)
Bruce M. McMaus, Michael Seidman, Karin Klingel, Honglin Luo

CHAPTER 8 Viral Diseases of the Skin (Pages: 115-139)
Zeena Y. Nawas, Stephen K. Tyring

CHAPTER 9 Viral Hemorrhagic Fevers (Pages: 141-150)
Gail Carson, Mike Bray, Cathy Roth

CHAPTER 10 Viral Disease of the Eye (Pages: 151-167)
Howard M. Newman

CHAPTER 11Antiretroviral Agent (Pages: 169-214)
Christine J. Kubin, Barbara S. Taylor, Scott M. Hammer

CHAPTER 12 Antiherpesvirus Agents (Pages: 215-237)
Claire L. Gordon, Christine J. Kubin, Scott M. Hammer

CHAPTER 13 Anti-Hepatitis Virus Agents (Pages: 239-270)
Matthew L. Scherer, Chelsea Sammons, Brian Nelson, Scott M. Hammer, Elizabeth Verna

CHAPTER 14 Antirespiratory Virus Agents (Pages: 271-290)
Marcus R. Pereira, Benjamin A. Miko, Monica Mehta, Scott M. Hammer

CHAPTER 15 Diagnosis of Viral Infections (Pages: 291-319)
Guy Boivin, Tony Mazzulli, Martin Petric

CHAPTER 16 Immune Responses to Viral Infection (Pages: 321-350)
Hendrik Streeck, Todd J. Suscovich, Galit Alter

CHAPTER 17 Immunization Against Viral Diseases (Pages: 351-370)
Julie E. Ledgerwood, Barney S. Graham

CHAPTER 18 Chronic Fatigue and Postinfective Fatigue Syndromes (Pages: 371-384)
Andrew R. Lloyd

Section II : The Agents

Part A : DNA VIRUSES

CHAPTER 19 Poxviruses (Pages: 385-413)
Stuart N. Isaacs, R. Mark Buller

CHAPTER 20Herpes Simplex Viruses (Pages: 415-445)
Richard J. Whitley, Bernard Roizman

CHAPTER 21 Cercopithecine Herpesvirus 1 (B Virus) (Pages: 447-457)
Richard J. Whitley

CHAPTER 22 Varicella-Zoster Virus (Pages: 459-480)
Anne A. Gershon, Michael D. Gershon

CHAPTER 23 Cytomegalovirus (Pages: 481-510)
Paul David Griffiths, Matthew Reeves

CHAPTER 24 Human Herpesvirus 6 and Human Herpesvirus 7 (Pages: 511-522)
Koichi Yamanishi, Yasuko Mori

CHAPTER 25 Epstein-Barr Virus (Pages: 523-547)
Joyce Fingeroth

CHAPTER 26 Kaposi's Sarcoma-Associated Herpesvirus (KSHV/HHV8) (Pages: 549-574)
Yuan Chang, Shou-Jiang Gao, Patrick S. Moore

CHAPTER 27 Adenoviruses (Pages: 575-597) Olli Ruuskanen, Jordan P. Metcalf, Matti Waris, Göran Akusjärvi

CHAPTER 28 Polyomaviruses (Pages: 599-623)
John E. Greenlee, Hans H. Hirsch

CHAPTER 29 Papillomavirus (Pages: 625-678)
William Bonnez

CHAPTER 30 Human Parvoviruses (Pages: 679-699)
Maria SÖderlund-Venermo, Kevin E. Brown, Dean D. Erdman

CHAPTER 31 Anelloviridae (Pages: 701-711)
Peter Simmonds, Colin P. Sharp

CHAPTER 32 Hepatitis B Virus (Pages: 713-770)
Darren J. Wong, Stephen A. Locarnini, Alexander J.V. Thompson

Part B : RNA VIRUSES

CHAPTER 33 Human Lymphotropic Viruses: HTLV-1 and HTLV-2 (Pages: 771-794)
Roberta L. Bruhn, Renaud Mahieux, Edward L. Murphy

CHAPTER 34 Human Immunodeficiency Virus (Pages: 795-840)
John C. Guatelli, Robert F. Siliciano, Daniel R. Kuritzkes, Douglas D. Richman

CHAPTER 35 Colorado Tick Fever and Other Arthropod Borne Reoviridae (Pages: 841-852)
Steven Yukl, Joseph K. Wong

CHAPTER 36 Rotaviruses (Pages: 853-872)
Manuel A. Franco, Juana Angel, Harry B. Greenberg

CHAPTER 37 Respiratory Syncytial Virus, Human Metapneumovirus, and Parainfluenza Viruses (Pages: 873-902)
John V. Williams, Pedro A. Piedra, Janet A. Englund

CHAPTER 38 Measles (Pages: 903-928)
William J. Moss, Diane E. Griffin

CHAPTER 39 Mumps Virus (Pages: 929-948)
John W. Gnann Jr., Donald R. Latner

CHAPTER 40 Zoonotic Paramyxoviruses (Pages: 949-966)
Danielle E. Anderson, Lin-Fa Wang

CHAPTER 41 Rhabdoviruses (Pages: 967-979)
Alan C. Jackson

CHAPTER 42 Filoviruses (Pages: 981-1007)
Mike Bray, Daniel S. Chertow

CHAPTER 43 Influenza Virus (Pages: 1009-1058)
Frederick G. Hayden, Peter Palese

CHAPTER 44 Bunyaviridae: Orthobunyaviruses, Phleboviruses, Nairoviruses, and Hantaviruses (Pages: 1059-1087)
Gregory J. Mertz, Clas Ahlm, Colleen B. Jonsson

CHAPTER 45 Arenaviruses (Pages: 1089-1111)
Daniel G. Bausch

CHAPTER 46 Enteroviruses (Pages: 1113-1142)
JosÉ R. Romero

CHAPTER 47 Rhinovirus (Pages: 1143-1164)
Wai-Ming Lee, James E. Gern

CHAPTER 48 Hepatitis A Virus (Pages: 1165-1188)
Sara E. Williford, Stanley M. Lemon

CHAPTER 49 Human Caliciviruses (Pages: 1189-1208)
Robert L. Atmar, Mary K. Estes

CHAPTER 50 Hepatitis E Virus (Pages: 1209-1229)
Harry R. Dalton, Nassim Kamar, Jacques Izopet

CHAPTER 51 Astrovirus (Pages: 1231-1242)
Carlos F. Arias, TOMÁS LÓPEZ

CHAPTER 52 Coronaviruses (Pages: 1243-1265)
J.S.M. Peiris

CHAPTER 53 Arthropod-Borne Flaviviruses (Pages: 1267-1311)
Lyle R. Petersen, Alan D.T. Barrett

CHAPTER 54 Hepatitis C Virus (Pages: 1313-1345)
Christopher Koh, Qisheng Li, Jake Liang

CHAPTER 55 Alphaviruses (Pages: 1347-1379)
David W. Smith, John S. Mackenzie, Ilya V. Frolov, Scott C. Weaver

CHAPTER 56 Rubella Virus (Pages: 1381-1393)
David W. Kimberlin

CHAPTER 57 Infections Caused by Bornaviruses (Pages: 1395-1407)
Ralf DÜrrwald, Norbert Nowotny, Martin Beer, Jens H. Kuhn

Part C : SUBVIRAL AGENTS

CHAPTER 58 Hepatitis D (Pages: 1409-1423)
Mario Rizzetto, Antonina Smedile, Alessia Ciancio

CHAPTER 59 Prion Diseases (Pages: 1425-1448)
Christina J. Sigurdson, Mee-Ohk Kim, Michael D. Geschwind

Subject Index (Pages: 1449-1489)

Editorial Reviews

5 Stars! from Doody

This book is a masterpiece. In 54 chapters, a world-renowned faculty has been assembled to comprehensively consider the pathogenic human viruses of medical importance. Constantly given short shrift in medical microbiology textbooks, viruses have long deserved a textbook of their own that integrates the basic science information with clinical, epidemiological, and therapeutic information, and this text does all that and more. The editors point out that clinical virology is the ""domain of molecular biologists, geneticists, pharmacologists, rnicrobiologists, immunologists, vaccinologists, practitioners of public health, epidemiologists, and clinicians, both pediatric and adult."" It is not an overstatement to say that individuals in any and all of these disciplines would benefit from having this book in their personal libraries. The book is divided into two sections: one describing viral syndromes/general agents, and one that considers individual agents on a pathogen-by-pathogen basis. The introduction provides a very useful and user-friendly overview of the sometimes confusing area of viral taxonomy, and the remarkable 16-page color insert provides some of the finest illustrations of classic viral syndromes ever collected in one text. A surprising feature of the text is its comprehensive and current reference list. For example, the chapter on Human Herpesvirus 8 goes far beyond the description of the association between this agent and Kaposi's sarcoma and delves into a very current overview of the viral genome, the effect of cytokines on the biology of the virus, and the current state of knowledge about the epidemiology of infection. This book fills a real void in the field, andis highly recommended as a comprehensive and important text for all medical school libraries, as well as the personal libraries of individuals who work with viruses in either the research or clinical care setting.

Mark R. Schleiss

Clinical Virology is a good, current, well-written resource for the wide range of individuals interested in the many aspects of virus biology and disease. Its consistent format makes locating specific information easy. The clinician may find the organization based on virus classification rather than symptoms a bit confusing, but will quickly discover the several different chapters devoted to agents that cause hepatitis, herpes, encephalitis, or hemorrhagic fever.

Journal of the American Medical Association

Reviewer: Rebecca T. Horvat, PhD, D (ABMM)(University of Kansas Medical Center)
Description: This is the third edition of a classic reference that reviews the current condition of clinical virology. The book is divided into two sections: the first reviews the clinical syndromes caused by viruses and the second contains chapters on specific viral pathogens. The last edition was published in 2002 and much has changed in clinical virology in those seven years.
Purpose: The purpose is to provide a comprehensive resource for "scientists and health care providers" on the changing nature of known viral pathogens and the discovery of new viral pathogens. It also provides reliable information on the rapid evolution of new methods used for testing, treatment, and prevention of viral diseases. This resource is clearly needed during a time of global travel and increasing recognition of new pathogens.
Audience: This book is written for professionals who work in the area of infectious disease. This would include scientists developing new antiviral agents and vaccines as well as practitioners making a diagnosis of infection in an increasingly vulnerable population. The authors of each chapter are respected authorities in virology and their contribution to this resource is clearly visible.
Features: Chapters in the first section review the clinical viral syndromes by organ system and illustrate the complexity of diagnosing viral diseases that can manifest with similar symptoms. This section also addresses the increased opportunity for viral infections in vulnerable populations, such as cancer and transplant patients, as well as neonatal patients. The large second section is classically organized by viral agents. These chapters provide details on the basic life cycle of the viruses, and the epidemiology and pathogenesis of viral infections in various hosts. Most of these chapters discuss diagnostic methods and treatment. Each chapter is packed with good references, diagrams of the disease process, and diagnostic markers used to determine the stage of viral disease.
Assessment: This is clearly one of the classic, need to have books for any scientist or healthcare provider who works in the area of viral infections. A large book, it weighs in at more than seven pounds, so would not be convenient to have available at the bedside. This is a reference that would be useful in an electronic format to provide this type of access.

Doody's Review Service