Coronavirus Replication and Reverse Genetics / Edition 1

Coronavirus Replication and Reverse Genetics / Edition 1

by Luis Enjuanes
ISBN-10:
364205997X
ISBN-13:
9783642059971
Pub. Date:
12/08/2010
Publisher:
Springer Berlin Heidelberg
ISBN-10:
364205997X
ISBN-13:
9783642059971
Pub. Date:
12/08/2010
Publisher:
Springer Berlin Heidelberg
Coronavirus Replication and Reverse Genetics / Edition 1

Coronavirus Replication and Reverse Genetics / Edition 1

by Luis Enjuanes
$169.99
Current price is , Original price is $169.99. You
$169.99 
  • SHIP THIS ITEM
    Qualifies for Free Shipping
  • PICK UP IN STORE
    Check Availability at Nearby Stores

Overview

Coronaviruses are the RNA viruses with the largest genome known to date (27 to 32 kb). Members of this virus family affect most domestic animal species, causing important socio-economical losses, and also infect humans. Human coronaviruses were known to cause the winter common cold, a mild infection without important pathological consequences except in immuno-compromised patients. Recently, two new human coronaviruses have emerged, one causing the Severe and Acute Respiratory Syndrome (SARS) that infected more than 8000 individuals, leading to more than 800 deaths in 32 countries. This epidemic mobilized the World Health Organization, which launched travel restrictions to certain parts of the world for the first time in the last 50 years. The fact that coronaviruses, as many other viruses, crossed the species barrier to infect humans has posed a serious challenge to scientists involved in animal and human health. Control of coronavirus-induced diseases can only be the consequence of research on virus molecular biology and pathogenesis. This book contains information on virus genome structure, mechanism of replication and transcription, and the development of tools that make possible reverse genetic studies to understand virus-host interactions and the molecular basis of virus pathogenesis. The book also provides essential information for the development of classical and recombinant vaccines to control coronavirus infections.


Product Details

ISBN-13: 9783642059971
Publisher: Springer Berlin Heidelberg
Publication date: 12/08/2010
Series: Current Topics in Microbiology and Immunology , #287
Edition description: Softcover reprint of hardcover 1st ed. 2005
Pages: 257
Product dimensions: 6.10(w) x 9.25(h) x 0.02(d)

Table of Contents

Coronavirus Genome Structure and Replication.- Coronavirus Transcription: A Perspective.- The Coronavirus Replicase.- Viral and Cellular Proteins Involved in Coronavirus Replication.- Coronavirus Reverse Genetics by Targeted RNA Recombination.- Coronavirus Reverse Genetics and Development of Vectors for Gene Expression.- Reverse Genetics of Coronaviruses Using Vaccinia Virus Vectors.- Development of Mouse Hepatitis Virus and SARS-CoV Infectious cDNA Constructs.
From the B&N Reads Blog

Customer Reviews