Cosmeceutical Science in Clinical Practice: Second Edition

by Neil S Sadick (Editor), Mary P Lupo (Editor), Zoe Diana Draelos (Editor)

Overview

Cosmeceuticals – skin care products that fall between a cosmetic and a pharmaceutical, with active ingredients that counter skin aging and promote skin rejuvenation – are an invaluable adjunct to the cosmetic dermatologist or plastic surgeon performing minimally invasive aesthetic procedures. This guide from expert researchers and practitioners explains how best to integrate the potential of cosmeceutical products into the best international clinical practice, with new chapters to cover the very latest developments in this area.

The Series in Cosmetic and Laser Therapy is published in association with the Journal of Cosmetic and Laser Therapy.

Product Details

ISBN-13:	9781138055506
Publisher:	CRC Press
Publication date:	06/21/2023
Series:	Series in Cosmetic and Laser Therapy
Edition description:	2nd ed.
Pages:	196
Product dimensions:	7.00(w) x 10.00(h) x (d)

About the Author

Neil S Sadick MD, FAAD, FAACS, FACP, FACPh
Weill Medical College of Cornell University
and Sadick Dermatology and Aesthetic Surgery
New York, New York, USA

Mary P Lupo MD, FAAD
Tulane University Medical Center
and Lupo Center for Aesthetic and General Dermatology
New Orleans, Louisiana, USA

Zoe Diana Draelos MD, FAAD
Duke University School of Medicine
Durham, North Carolina, USA
and Dermatology Consulting Services
High Point, North Carolina, USA

Table of Contents

1. Clinical uses of copper in skin aging and wound healing

2. Ultrapotent Antioxidants and Anti-inflammatories

3. Cosmeceutical Peptides

4. Growth Factors, Cellular Secretome and Exosomes

5. Stem Cell derived cosmetics and their use in clinical practice

6. Matrix Metalloproteinases

7. Retinoids

8. Neurotransmitter-Affecting Peptides

9. Hyperpigmentation

10. Cosmeceuticals for Hair and Nails

11. Photoprotection (polypodium leucotomos, UV and IR blockers)

12. Nutraceuticals

13. New Delivery Systems for Novel Compounds

14. Cosmeceuticals in Dermatologic Conditions

Editorial Reviews

Reviewer: Patricia Wong, MD (Private Practice)
Description: This book discusses the existing data and science on various ingredients in topical cosmeceuticals. It reviews the basic science behind such claims from a physiologic standpoint.
Purpose: Consumers spend billions of dollars on cosmetic products. The aesthetic industry is not required to adhere to the same standards of scrutiny as medications in the U.S. Furthermore, the language on beauty product labels can be misleading for consumers. Descriptions such as "appears to diminish fine lines" or "use for smoother, firmer looking skin" promise real results in the mind of users. Accordingly, the purpose of this book is to understand what formulations are most helpful for addressing patients' concerns such as anti-aging and hyperpigmentation.
Audience: The audience for this book includes dermatologists with a cosmetic practice emphasis.
Features: Multiple chemical reactions may take place in the skin before ingredients are converted to their active form; that is, the form that can be metabolized in the skin and produce the intended effect. Absorption through the stratum corneum is also an important consideration that can affect efficacy. The book discusses the active forms of various ingredients as well as the difficulty in stabilizing the compounds. It also describes agents in the context of how their effects should work on a cellular level and the studies upon which these mechanisms of action are based. Unfortunately, there is a paucity of data comparing actives to one another in well-designed clinical trials. In many instances, the information suggesting improvement/corrections is based on short-term studies with a small number of subjects. It is important to be aware of these limitations when evaluating cosmetic products and making recommendations to patients.
Assessment: Those who read this book will be current on cosmetic formulations and their purported mechanisms of action. However, much more information needs to be uncovered to determine which ingredients make a big difference, which concentration of a given chemical/botanical is most desirable, which forms are most stable, and which vehicles allow the best penetration to occur to reach the dermis. Individuals will have a better understanding when reading product labels, but what to recommend as the most effective remains unanswered.

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