Cyclodextrins in Pharmacy / Edition 1

by Karl-Heinz Frïmming, J. Szejtli

Overview

Nearly three thousand papers and patents are dedicated to the actual or potential uses of cyclodextrins in pharmacy and pharmaceutical formulations. This is the first book written for pharmacists and pharmaceutical technologists which not only critically summarizes the enormous amount of literature available, but which can be used as a handbook when looking for solutions to practical problems.
The fundamentals — chemistry of cyclodextrins and their derivatives — their physical and chemical properties are condensed to the most relevant items in Chapters 1 and 2. Chapter 3 deals with the adsorption, metabolism and toxicological properties of cyclodextrins. Chapter 4 explains the formulation, structure, composition and advantageous effects of the cyclodextrin inclusion complexes. Chapter 5 describes the methods for preparation and characterization of drug/cyclodextrin complexes. Chapters 6 and 7 are dedicated to the pharmacokinetics, biopharmaceutical and technological aspects of drug/CD complexes. Chapter 8 treats the application and effects of cyclodextrins in various drug formulations. The Appendix comprises a collection of recipes for any type of drug formulation.
This book is aimed at those who use cyclodextrins in drug formulations, to improve the properties of existing drug formulations, or who want to prepare quite new formulations.

Product Details

ISBN-13:	9780792321392
Publisher:	Springer Netherlands
Publication date:	11/30/1993
Series:	Topics in Inclusion Science , #5
Edition description:	1994
Pages:	225
Product dimensions:	6.14(w) x 9.21(h) x 0.02(d)

Table of Contents

1. Cyclodextrins.- 2. Cyclodextrin Derivatives.- 3. Pharmacokinetics and Toxicology of Cyclodextrins.- 4. Cyclodextrin Inclusion Complexes.- 5. Preparation and Characterization of Cyclodextrin Complexes.- 6. Pharmacokinetics and Biopharmaceutics.- 7. Pharmaceutical-Technological Aspects of Cyclodextrins in Drug Formulation.- 8. Cyclodextrins in Various Drug Formulations.- 9. Appendix: Recipes.- 10. Legal Status of Cyclodextrins.

Editorial Reviews

Summarizes the thousands of papers and patents produced each year on the general properties and specific applications in pharmacy of the cyclodextrins. Considers the physical, chemical, and toxicological properties; adsorption and metabolism; formulation, structure, composition and effects of complexes; and other aspects. A reference for those who use the chemicals in drug formulations or are involved in improving existing formulations or preparing novel ones. Annotation c. Book News, Inc., Portland, OR (booknews.com)

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