Electrical Properties of Cells: Patch Clamp for Biologists

by Louis J. DeFelice

Overview

DeFelice presents this intricate subject in an easy-to-follow, stepwise fashion: he reviews the fundamentals of electricity; transfers those principles to a biological context; and expands the discussion to encompass the subject's practical dimensions. Clear definitions and intuitive descriptions characterize the presentation, which is complemented by over 150 drawings and graphs. Mathematics is kept to the minimum necessary. The text covers both excitable and non-excitable membranes and includes the plasma membrane as well as intracellular membranes.
A unique, ‘electronics-made-simple' appendix, designed specifically for biologists, treats the operational amplifiers used in patch clamp, and other appendices offer solutions to equations and examples that illustrate principles.

Product Details

ISBN-13:	9780306453458
Publisher:	Springer US
Publication date:	07/31/1997
Series:	The Language of Science Series
Edition description:	1997
Pages:	244
Product dimensions:	5.98(w) x 9.02(h) x 0.03(d)

Table of Contents

1. Basics.- 2. Bioelectricity.- 3. Applications.- Appendix 1. Operational Amplifiers.- Buffer.- Voltage Amplifier.- Current-to-Voltage Converter.- Appendix 2. Solution to Nernst-Planck.- Appendix 3. All Kinds of Averages.- Appendix 4. How Money Grows.

Editorial Reviews

An aid to biologists working with the patch clamp and a guide to the more advanced texts on it. Covers the basics of electricity and its manipulation and the features of bioelectricity, then surveys applications, including the Boltmann equation, gating currents, the gap junction model, action potentials composed of ion channel currents, proteins as capacitors, transport across the nuclear pore, and ion channels in sperm. Annotation c. by Book News, Inc., Portland, Or.

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