Energetics of Secretion Responses: Volume I

by J.W.N. Akkerman

Overview

Provides a multidisciplinary approach to the study of energetics of secretion responses by combining the knowledge and expertise of leading authorities from various fields.

Product Details

ISBN-13:	9781351365925
Publisher:	CRC Press
Publication date:	01/15/2019
Series:	CRC Press Revivals
Sold by:	Barnes & Noble
Format:	eBook
Pages:	158
File size:	3 MB

About the Author

Jan-Willem N. Akkerman PhD is the Director of the Laboratory of Haematology in the Department of Haematology at the University of Utrecht, The Netherlands. He received his Ph.D. degree in 1975 on a thesis entitled "Human Platelet Glycolysis" and was a visiting staff member at the Thrombosis Research Center at Temple University, Philadelphia, Pa. In 1978.

His research efforts are in the field of thrombosis and atherosclerosis, with special emphasis on the role of blood platelets and the mechanisms that make these cells responsive to platelet-activating agents. His current research interests are the energetics of platelet functions, mechanisms for signal transduction, and abnormal platelet behaviour in patients with bleeding disorders or hyperaggregability.

Table of Contents

1. Introduction 2. Cellular Energetics 3. PreStimulation Events: Biosynthesis and Storage of Secretory Proteins 4. Transport and Storage of Biogenic Amines in Adrenal Chromaffin Granules 5. Maintenance of Responsivity 6. Energy-Dependent Steps in Signal Processing: Ligand-Induced Surface Receptor Movement and Transmembrane Interactions 7. The Role of Membrane Potentials and of Intracellular pH in Secretory Cell Stimulation 8. Phosphoinositide Metabolism. Index