Fatal Attractions: Protein Aggregates in Neurodegenerative Disorders

by V.M.-Y. Lee (Editor), J.Q. Trojanowski (Editor), L. Buee (Editor), Y. Christen (Editor)

Overview

In this volume are contributions based on a meeting arranged by the WH O and the Foundation IPSEN. The scientists focus on neurodegenerative disorders like Alzheimer's Disease, Chromosome 17-Linked Dementia, Par kinson's Disease and disorders with tauopathies.

Product Details

ISBN-13:	9783662040560
Publisher:	Springer-Verlag New York, LLC
Publication date:	03/09/2013
Series:	Research and Perspectives in Alzheimer's Disease
Sold by:	Barnes & Noble
Format:	eBook
File size:	4 MB

Table of Contents

The Role of ?-Synuclein in Parkinson’s Disease: A Biophysical Analogy to A? and Alzheimer’s Disease.- Purification of Lewy Bodies and Identification of ? -Synuclein as a Major Component of Lewy Bodies.- Mutational Analysis of Tau in Chromosome 17-Linked Dementia.- Missense and Splice Site Mutations in Tau Associated with FTDP-17: Multiple Pathogenic Mechanisms.- Tau Mutations: Genetics and Pathogenetic Mechanisms.- Tauopathies and ?-Synucleinopathies.- Distinct Tau Gene Mutations Induce Specific Dysfunctions/Toxic Properties in Tau Proteins Associated with Specific FTDP-17 Phenotypes.- Neurodegenerative Disorders with Tauopathies: Mad Tau Diseases?.- Tau Protein: Role in Intracellular Traffic and Development of Cell Polarity.