Genes, Brain and Development: The Neurocognition of Genetic Disorders

by Marcia A. Barnes (Editor)

Overview

Genetic syndromes and neurodevelopmental disorders that have a genetic basis are associated with cognitive and academic disabilities. Genes, Brain and Development reviews the connections between genes, brain, and behavior for a range of genetic disorders, and also considers lifespan and treatment issues. The content further explores what is known about development in neurogenetic disorders, particularly in the domains of language and mathematics, and shows how this knowledge is pertinent to understanding both these specific disorders, and disorders of language and math more generally. This will be essential reading for a wide range of brain scientists and developmental clinicians, including neuropsychologists, cognitive psychologists, neurologists, psychiatrists, pediatricians, neuroscientists and geneticists.

Product Details

ISBN-13:	9780521685368
Publisher:	Cambridge University Press
Publication date:	01/07/2010
Series:	Series for the International Neuropsychological Society
Pages:	236
Product dimensions:	6.80(w) x 9.60(h) x 0.70(d)

About the Author

Marcia A. Barnes is Professor, Department of Pediatrics, University of Texas Health Science Center at Houston.

Table of Contents

List of Contributors ix

Preface xi

Acknowledgments xvi

Section 1 Connecting genes, brain, and behavior in neurodevelopmental disorders 1

1 Intergenerational effects of mutations in the fragile X mental retardation 1 gene. Fragile X: A model of X-linked mental retardation and neurodegeneration Mariya Borodyanskaya Sarah Coffey Michele Y. Ono Randi J. Hagerman 3

2 Autism: Genes, anatomy, and behavioral outcome Emma Esser Saasha Sutera Deborah Fein 19

3 Development in spina bifida: Neurobiological and environmental factors Marcia A. Barnes Heather B. Taylor Susan B. Landry Lianne H. English 53

Section 2 Genetic disorders and models of neurocognitive development 83

4 Language and communication in autism spectrum disorders Susan Ellis Weismer 85

5 Language development in children with Williams syndrome: New insights from cross-linguistic research Stavroula Stavrakaki 105

6 Language in Down syndrome: A life-span perspective Jean A. Rondal 122

7 Genetic disorders as models of mathematics learning disability; Fragile X and Turner syndromes Melissa M. Murphy Mich?le M. M. Mazzocco Michael McCloskey 143

8 A developmental approach to genetic disorders Sarah J. Paterson 175

9 The use of strategies in embedded figures: Tasks by boys with and without organic mild mental retardation: A review and some experimental evidence Anastasia Alevriadou Helen Tsakiridou 199

Index 216