Genetics 101

Genetics 101

by Michael Windelspecht
Genetics 101

Genetics 101

by Michael Windelspecht

Hardcover(New Edition)

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Overview

What should the average person know about science? Because science is so central to life in the 21st century, science educators and other leaders of the scientific community believe that it is essential that everyone understand the basic concepts of the most vital and far-reaching disciplines. Genetics 101 does exactly that. This accessible volume provides readers - whether students new to the field or just interested members of the lay public - with the essential ideas of genetics using a minimum of jargon and mathematics. Concepts are introduced in a progressive order so that more complicated ideas build on simpler ones, and each is discussed in small, bite-sized segments so that they can be more easily understood.

Product Details

ISBN-13: 9780313333811
Publisher: Bloomsbury Academic
Publication date: 05/30/2007
Series: Science 101
Edition description: New Edition
Pages: 216
Product dimensions: 6.14(w) x 9.21(h) x 0.56(d)
Age Range: 14 - 18 Years

About the Author

Michael Windelspecht is Assistant Professor of Biology at Appalachian State University. He is the author or co-author of numerous works for Greenwood, including The Digestive System and The Lymphatic System in the Human Body Systems series.

Table of Contents


Series Foreword     xi
Acknowledgments     xiii
Abbreviations     xv
Introduction     1
Genetics as a Science     7
Corn and Wheat: Birth of Civilization and Genetics     7
Gregor Mendel and Genetics     10
Important Genetic Terms     18
Thomas Hunt Morgan and the Fly Lab     20
Is Inheritance as Simple as Mendel Suggested?     26
Incomplete Dominance     27
Multiple-Allele Systems     28
Gene Interactions     29
DNA as the Hereditary Molecule     31
Griffith and the Transformation of DNA     32
Avery and the Transforming Principle     33
DNA or Protein? The Hershey-Chase Experiments     35
The Structure of DNA     37
Chargaff and Complementation     37
Wilkins, Franklin, and DNA Crystals     39
Pauling and Proteins     40
Watson and Crick Unveil the Double Helix     41
Meselson, Stahl, and DNA Replication     44
DNA versus RNA     47
Genetics at the Molecular Level     51
Molecular Mechanism of DNA Replication     51
One-Gene, One-Enzyme     54
Structure of a Gene     57
Transcription     60
RNA Editing     63
The Genetic Code     65
Translation     67
Protein Structure     71
Turning Genes On and Off     74
Studying the Gene     77
Restriction Endonucleases     77
Gel Electrophoresis     79
Cloning     83
Polymerase Chain Reaction (PCR)     85
DNA Libraries     88
Southern Blotting     90
DNA Sequencing     91
DNA Microarrays     94
Molecular Markers     95
Genetic Maps     98
Changes to the Genetic Material     101
Chromosome Structure     101
Observing Chromosomes     105
Changes in Chromosome Structure     107
Changes in Chromosome Number     111
Types of Mutations     114
Agents of Mutation     116
Transposons-The "Jumping Genes"     120
Manipulating the Gene and Genome     125
Recombinant DNA     125
Transgenic Plants and Genetically Modified Organisms (GMOs)     127
Gene Therapy     130
Knock-Out Mouse     134
RNA Interference     137
Site-Directed Mutagenesis     140
Applications of Genetics     143
Population Genetics     143
DNA Fingerprinting     147
Cancer Genetics     149
Behavioral Genetics     152
Quantitative Genetics     158
Genetics of Complex Diseases     164
Schizophrenia     164
Narcolepsy     166
Diabetes     157
Retinitis Pigmentosa     169
Glossary     173
References and Resources     183
Print     183
Web     184
Index     189
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