Table of Contents
About the Editors, vii
List of Contributors, viii
Preface, xii
Acknowledgments, xiii
Part 1 The Aging Brain in Neurology, 1
1 The Biology of Aging: Implications for Diseases of Aging and Health Care in the Twenty-First Century, 3Douglas F. Watt
2 Functional Changes Associated with the Aging Nervous System, 38Julie A. Schneider and Chunhui Yang
Part 2 Assessment of the Geriatric Neurology Patient, 69
3 Approach to the Geriatric Neurology Patient: The Neurologic Examination, 71Marwan N. Sabbagh and Anil K. Nair
4 Assessment of Cognitive Status in Geriatric Neurology, 85
4.1 Mental Status Examination in the Geriatric Neurology Patient, 87Papan Thaipisuttikul and James E. Galvin
4.2 Neuropsychology in Geriatric Neurology, 98Donald J. Connor and Marc A. Norman
5 Cognitive Reserve and the Aging Brain, 118Adrienne M. Tucker and Yaakov Stern
6 Gait Disorders in the Graying Population, 126Joe Verghese and Jessica Zwerling
7 Imaging of the Geriatric Brain, 136
7.1 Structural Neuroimaging in Degenerative Dementias, 138Liana G. Apostolova
7.2 Functional Imaging in Dementia, 146Adam S. Fleisher and Alexander Drzezga
7.3 Amyloid Imaging, 162Anil K. Nair and Marwan N. Sabbagh
8 Clinical Laboratory Investigations in Geriatric Neurology, 170Geoffrey S. Baird and Thomas J. Montine
Part 3 Neurologic Conditions in the Elderly, 181
9 Cognitive Impairment and the Dementias, 183
9.1 Mild Cognitive Impairment, 187Ranjan Duara, Miriam Jocelyn Rodriguez, and David A. Loewenstein
9.2 Alzheimer’s Disease, 200Martin R. Farlow
9.3 Dementia with Lewy Bodies, 208Clive Ballard
9.4 Vascular Cognitive Impairment, 224Helena C. Chui and Freddi Segal-Gidan
9.5 Frontotemporal Dementia, 239David Perry and Howard Rosen
9.6 Primary Progressive Aphasia, 251Maya L. Henry, Stephen M. Wilson, and Steven Z. Rapcsak
9.7 Prion Diseases, 267Michael D. Geschwind and Katherine Wong
9.8 Normal Pressure Hydrocephalus, 281Norman R. Relkin
10 Depression in the Elderly: Interactions with Aging, Stress, Chronic Pain, Infl ammation, and Neurodegenerative Disorders, 287Douglas F. Watt
11 Cerebrovascular Diseases in Geriatrics, 302Patrick Lyden, Khalil Amir and Ilana Tidus
12 Movement Disorders, 313
12.1 Parkinson’s Disease, 315Robert Fekete and Joseph Jankovic
12.2 Essential Tremor and Other Tremor Disorders, 325Holly Shill
12.3 Progressive Supranuclear Palsy, 333Virgilio Gerald H. Evidente
12.4 Corticobasal Degeneration, 344Katrina Gwinn
13 Sleep Disorders, 347Sanford Auerbach
14 Autonomic Dysfunction and Syncope, 358Rohit R. Das
15 Geriatric Epilepsy, 370David V. Lardizabal
16 Vertigo and Dizziness in the Elderly, 379Terry D. Fife and Salih Demirhan
17 Disorders of the Special Senses in the Elderly, 396Douglas J. Lanska
18 Nervous System Infections, 460Ronald Ellis, David Croteau, and Suzi Hong
19 Delirium, 478Alan Lerner, Stefani Parrisbalogun, and Joseph Locala
20 Headache in the Elderly, 486Brian McGeeney
21 Neuromuscular Disorders, 494Heber Varela and Clifton Gooch
Part 4 Therapeutics for the Geriatric Neurology Patient, 519
22 Neurosurgical Care of the Geriatric Patient, 521David Fusco, Rasha Germain, and Peter Nakaji
23 Treatment of Dementia, 556
23.1 Evidence-Based Pharmacologic Treatment of Dementia, 557Jasmeet Singh, Marwan N. Sabbagh, and Anil K. Nair
23.2 Immunotherapy for Alzheimer’s Disease, 574Michael Grundman, Gene G. Kinney, Eric Yuen, and Ronald Black
24 Geriatric Psychopharmacology, 586Sandra A. Jacobson
25 Nonpharmacologic Treatment of Behavioral Problems in Persons with Dementia, 615Gary A. Martin and John Ranseen
26 Expressive Art Therapies in Geriatric Neurology, 630Daniel C. Potts, Bruce L. Miller, Carol A. Prickett,Andrea M. Cevasco, and Angel C. Duncan
Part 5 Important Management Issues Beyond Therapeutics in the Geriatric Neurology Patient, 645
27 Dietary Factors in Geriatric Neurology, 647Yian Gu and Nikolaos Scarmeas
28 Exercising the Brain: Nonpharmacologic Interventions for Cognitive Decline Associated with Aging and Dementia, 669Brenna A. Cholerton, Jeannine Skinner, and Laura D. Baker
29 Driving Impairment in Older Adults, 682Anne D. Halli-Tierney and Brian R. Ott
30 Elder Abuse and Mistreatment, 699Elliott Schulman, Ashley Roque, and Anna Hohler
31 Advocacy in Geriatric Neurology, 707Glenn Finney and Anil K. Nair
Index, 713