Heart Function and Metabolism: Proceedings of the Symposium held at the Eighth Annual Meeting of the American Section of the International Society for Heart Research, July 8-11, 1986, Winnipeg, Canada / Edition 1

by Naranjan S. Dhalla, Grant N. Pierce, Robert E. Beamish

Overview

Proceedings of the Symposium held at the 8th Annual Meeting of the American Section of the International Society for Heart Research, July 8-11, 1986, Winnipeg, Canada

Product Details

ISBN-13:	9780898388657
Publisher:	Springer US
Publication date:	02/28/1987
Series:	Developments in Cardiovascular Medicine , #66
Edition description:	1987
Pages:	432
Product dimensions:	6.10(w) x 9.25(h) x 0.04(d)

Table of Contents

A. Special Lecture.- 1. Molecular Biology and Cardiac Function, Past, Present and Future.- B. Electrical Events and Ions.- 2. Regulation of Calcium Slow Channels and Potassium Channels of Cardiac Muscle by Cyclic Nucleotides and Metabolism.- 3. Potassium Channels Identified with Single Channel Recordings and Their Role in Cardiac Excitation.- 4. Na and Ca Channels in the Heart.- 5. Sodium Pathways In and Out of the Cardiac Cells: Relationship to Inotropy.- 6. Nondriven Electrical Activity in Cardiac Ventricular Fibers.- 7. Regulation of Cl? Activity in Ventricular Muscle: Cl?/HCO-3 Exchange and Na+ — dependent Cl? Cotransport.- C. Sarcolemmal Functions.- 8. Parasympathetic Control of the Heart: Subcellular Mechanisms.- 9. Role of Phosphatidylethanolamine N-Methylation on Ca2+ Transport in Cardiac Membranes.- 10. Na+ - Ca2+ Exchange in Cardiac Sarcolemmal Vesicles.- 11. Na/K Pump Function in Cultured Embryonic Chick Heart Cells.- 12. Characteristics of Ca2+/Mg2+ ATPase in Heart Sarcolemma Treated with Trypsin.- D. Sarcoplasmic Reticulum Function.- 13. Depression of Canine Ventricular Sarcoplasmic Reticulum by the Calcium Channel Agonist, Bay K 8644.- 14. Biophysical Aspects of Ca2+ — Transport Sites in Skeletal and Cardiac Sarcoplasmic Reticulum (Ca2+ + Mg2+)—ATPase.- 15. Mechanisms of Sarcoplasmic Reticulum Functions and Consequences for Muscle Activity.- 16. Protein Phosphorylation in Cardiac Sarcoplasmic Reticulum and Its Functional Consequences.- 17. The Ca2+ ATPase of Cardiac Muscle Sarcoplasmic Reticulum.- E. Contractile Protein Functions.- 18. Contractile and Regulatory Proteins in Cardiovascular System.- 19. Distribution of Cardiac Myosin Isozymes in Human and Rat Heart-Immunohishemical Study Using Monoclonal Antibodies.- 20. Remodelling of theMyocyte at a Molecular Level - Relationship Between Myosin Isoenzyme Population and Sarcoplasmic Reticulum.- 21. Isomyosins and Isoactins in Mammalian Myocardium.- 22. Crossbridge Mechanisms of Contraction in Vascular Smooth Muscle.- F. Functional Aspect of Metabolism.- 23. Control of Glucose Uptake and Utilization in the Myocardium.- 24. Blockade of Sugar Transport Decreases Contractility of Aortic Smooth Muscle.- 25. Control of Energy Transport in Cardiac Muscle. Dissociation of ATP Levels from Contractile Function; Cardiac Failure Due to Phosphocreatine Deficiency.- 26. Creatine Kinase and Mechanical Properties of Rat Ventricular Muscle.- 27. Hemodynamic Performance of Creatine-Depleted Rat Heart in Isolated Blood-Perfused Working Preparation.- 28. Localization of Glucose-6-Phosphatase (G-6-Pase) in the Rat Heart Muscle Cells.