Hormone Resistance Syndromes

by J. Larry Jameson (Editor)

Overview

Leading clinicians review in depth the clinical and molecular aspects of the hormone resistance syndromes caused by receptor mutations. These mutations are involved in a large number of disorders, including dwarfism, Laron syndrome, pseudohypoparathyroidism, insulin resistance, resistance to thyroid hormone, glucocorticoid resistance, hereditary resistance to vitamin D, and estrogen resistance. Throughout, the book's distinguished contributors not only summarize the clinical features of these and related disorders, but also illuminate their molecular bases. Hormone Resistance Syndromes provides an authoritative summary and standard reference for all those clinicians and researchers actively studying these mutations today and affords a unique opportunity to understand hormone action in normal physiology.

Product Details

ISBN-13:	9781592596980
Publisher:	Springer-Verlag New York, LLC
Publication date:	01/26/1999
Series:	Contemporary Endocrinology , #14
Sold by:	Barnes & Noble
Format:	eBook
File size:	11 MB
Note:	This product may take a few minutes to download.

About the Author

Jameson, J. Larry, MD, PhD (Northwestern Univ)

Table of Contents

1 Dwarfism: GHRH Resistance.- 2 Laron Syndrome: Primary Growth Hormone Resistance.- 3 Pseudohypoparathyroidism.- 4 Hereditary Resistance to Vitamin D.- 5 Decreased Responsiveness to Extracellular Ca2+ Owing to Abnormalities in the Cao2+-Sensing Receptor.- 6 Resistance to TSH.- 7 Thyroid Hormone Resistance.- 8 Diabetes Mellitus: Insulin Resistance.- 9 LH Insensitivity Syndrome.- 10 FSH Resistance.- 11 Genetic Alterations of Androgen Receptor Function.- 12 Retained Müllerian Ducts: AMH Resistance Syndrome.- 13 Adrenal Insufficiency: ACTH Resistance.- 14 Glucocorticoid Resistance and Hypersensitivity.

Editorial Reviews

Clinicians review the clinical and molecular aspects of the hormone resistance syndromes caused by receptor mutations. Among the disorders they examine are dwarfism, Laron syndrome, pseudohypoparathyroidism, insulin resistance, resistance to thyroid hormone, glucocorticoid resistance, hereditary resistance to vitamin D, and estrogen resistance. The articles succinctly summarize the known information for clinicians and researchers in endocrinology or physiology who working with such mutations, and provide ample references for more detailed investigation. Annotation c. by Book News, Inc., Portland, Or.

Booknews

"Larry Jameson has excellently well introduced the Hormone resistance syndrome..."- Cellular and Molecular Biology

From the Publisher