Insulin Resistance Syndrome and Neuropsychiatric Disease

by Natalie L. Rasgon (Editor)

Overview

This is the first book of its kind to tie the metabolic syndrome with psychiatric disorders and raise the possibility that common antipsychotic treatments may have this type of adverse effect on patients. Presenting a complete overview and the relationship between insulin resistance syndrome and psychiatric and cognitive disorders, the book will be a welcome addition to the library of any psychiatrist, neurologist, endocrinologist, or research scientist. The book also discusses new treatments to help prevent metabolic complications among patients with neuropsychiatric illnesses, including schizophrenia, Alzheimer’s Disease, and major depression.

Product Details

ISBN-13:	9780849382086
Publisher:	Taylor & Francis
Publication date:	04/09/2008
Series:	Medical Psychiatry Series , #38
Pages:	168
Product dimensions:	6.00(w) x 9.00(h) x (d)

About the Author

NATALIE L. RASGON is Professor, Departments of Psychiatry and Behavioral Sciences, Obstetrics and Gynecology, Stanford University, California, and she is Director of the Center for Neuroscience in Women’s Health at the Stanford School of Medicine and Stanford Neuroscience Institute. Dr. Rasgon received her M.D. and Ph.D. in Obstetrics and Gynecology and Pathological Physiology from the Central Institute of Postgraduate Medical Education, Central Institute of General Pathology and Pathological Physiology, Academy of Medical Sciences, Moscow, Russia. Dr. Rasgon is the author of over 124 peer-reviewed articles, more than 25 book chapters, and is a reviewer for more than 25 medical journals specific to psychiatry, neuropharmacology, and obstetrics and gynecology.

Table of Contents

Introduction. The Metabolic Syndrome: Much Ado About (almost) Nothing. Insulin Resistance in Schizophrenia and Major Depression. Insulin Resistance Syndrome and Alzheimer’s Disease. Insulin Resistance, Depressive Disorders, and Alzheimer’s Disease. Conclusion

Editorial Reviews

Reviewer: Jeffrey Rado, MD (Rush University Medical Center)
Description: This is a scientific review of the literature regarding insulin resistance (i.e. hyperglycemia, diabetes mellitus) and its relationship to psychiatric disorders such as schizophrenia and dementia. It is less of a clinical manual and more of an in-depth review of the topic. Readers will definitely develop an appreciation for the scope and significance of this perplexing clinical problem.
Purpose: The purpose is to educate clinicians in all specialties on the pathophysiology and interrelationships between diabetes, depression, and dementia.
Audience: Although the intended audience is clinicians in all specialties, psychiatrists (residents and attendings alike) and endocrinologists would likely find it most useful and informative.
Features: The concept of metabolic syndrome is discussed at length, including some healthy criticism of a sometimes vague concept. Significant time is spent in exploring the link between insulin resistance and specific psychiatric illnesses (i.e. depression, dementia, and schizophrenia). The molecular and epidemiological links are thoroughly discussed. There is an extensive bibliography for each chapter, but the book could have been improved by more illustrations.
Assessment: Overall, this book is easy to read and most clinicians will find it useful in helping them to understand the field better. The book is written in a very matter-of-fact way, making it easier to understand complicated issues. There is a thorough discussion of the many unanswered and unexplained findings in this burgeoning new area of research.

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