Landmark Papers in Pain: Seminal Papers in Pain with Expert Commentaries

by Paul Farquhar-Smith, Pierre Beaulieu, Siïn Jaggar

Overview

Pain Medicine, a relatively new specialty, has proven increasingly relevant to medical practitioners in every field. The specialism of pain has emerged over the past 50 years, largely due to the persistence of experts and new medical evidence that points to its necessity. Today, it is a distinct and integral part of global medical practice.

Landmark Papers in Pain offers a comprehensive inventory of over 80 key studies in pain medicine from the last 100 years. Each paper is accompanied by a concise commentary on the significance of the original findings written by an expert in pain. The reviews discuss how the paper influenced the development of the speciality, and how the findings have advanced our global comprehension of pain. Together, the selected papers and reviews chart the growth of an embryonic field into the modern speciality of pain medicine.

Complied by leading specialists in the field, the papers included in this book are significant for any student, researcher, clinical practitioner, or medical historian interested in pain medicine. Organised into eight distinct topics and cross-referenced by topics and author of original paper, the book is comprehensive in its coverage and easy to use. A review of the contemporary and historical research that shaped the speciality of pain, Landmark Papers in Pain is essential reading for all medical practitioners with an interest in pain medicine.

Product Details

ISBN-13:	9780198834359
Publisher:	Oxford University Press
Publication date:	09/26/2018
Series:	Landmark Papers In
Pages:	334
Product dimensions:	9.60(w) x 6.70(h) x 0.80(d)

About the Author

Paul Farquhar-Smith, The Royal Marsden NHS Foundation Trust, London, UK, Consultant in Pain Managment and Anaesthetics,Pierre Beaulieu, Department of Anesthesiology and Professor, Department of Pharmacology, Faculty of Medicine, University of Montreal, Montreal, Canada, Professor and Director, Siân Jagger, Royal Brompton & Harefield NHS Foundation Trust, London, UK, Consultant Anaesthetist

Dr Paul Farquhar-Smith, MA, MB, BChirFRCA, PhD, FFPMRCA, FFICM, is at present a Consultant in Pain Medicine and Anaesthesia at The Royal Marsden NHS Foundation Trust in London, UK. He specialises in pain in cancer patients and survivors (post-surgical chronic pain, chemotherapy induced neuropathy), and anaesthesia for breast and reconstructive surgery.

Dr Pierre Beaulieu is at present a Professor of Anesthesiology and Pharmacology at Universite de Montreal in Canada. He specialises in the pharmacology and neurobiology of pain, the use of cannabinoids for treatment of pain, and in local anaesthetics

Dr Siân Jaggar is at present a Consultant in Anaesthesia at Royal Brompton & Harefield NHS Foundation Trust in London, UK. She specialises in adult and paediatric cardiothoracic anaesthesia and pain relief. She has a particular interest in education as a tool to enhance understanding between different working groups. She is the Royal College deputy regional advisor for the North West Thames region and the lead for less than full time trainees in this region.

Table of Contents

Section 1: Historical1. Local anaesthetic substitutes for cocaine, JAW (Tony) Wildsmith2. Innovative concepts in pain management, Ben M. Thomas3. Explaining reflex sympathetic dystrophy, Sebastian Brandner and Brigitta Brandner4. The rediscovery of paracetamol, Alain Eschalier and Christophe Mallet5. The pharmacology of placebos, Fabrizio Benedetti6. Understanding the responsiveness of c-fibres, Jean-Sebastien Walczak7. A new theory of pain, Tony Dickenson8. Three determinants of pain, Manon Choiniere and Gabriella Page9. Purinergic nerves: a new type of nerve, Guy Rousseau10. Genetic differences in opiate receptors, Jeffrey S. Mogil11. Endogenous opioids in placebo-induced analgesia, Pierre Rainville12. Ethical pain experimentation in conscious animals, Eric Troncy13. Local anaesthetic creams, Argyro Fassoulaki14. The backpain revolution, Cathy Price15. The mechanism of aspirin, Pierre Sirois and Pedro D'orleans-Juste16. Mechanisms of visceral pain in IBS, Yasser Al Omran and Qasim Aziz17. The effects of morphine on the central nervous system, Philippe Richebe and Cyril Rivat18. Opiods in palliative care, Joan Hester19. Endogenous opioids in the central nervous system, Tony Dickenson20. Spinal opioid analgesia in the rat, Craig W. StevenSection 2: Firsts21. The key role of NGF in inflammatory pain processing, Paul Farquhar-Smith22. Mapping of neurotrophin receptors on adult sensory neurons, Elizabeth J. Bradbury and Nicholas D. James23. Plasticity in somatic receptive fields after nerve injury, Stephen R. Humble24. Peripheral neural mechanisms of cutaneous hyperalgesia and heat pain, Amanda Klein and Matthias Ringkamp25. The Cloning and Characterization of CB1, Mary E. Abood and Thomas Gamage26. Deorphanisation of ORL-1/LC132 by reverse pharmacology in two landmark studies, Mark F. Bird and David Lambert27. The capsaicin receptor, Istvan Nagy28. Vanilloid receptor 1 in inflammatory thermal hyperalgesia, Istvan Nagy29. A signature of pain in the brain, Pierre Rainville30. Cytokines as central to peripheral sensitisation and hyperalgesia, John Schutzer-Weissmann31. Endogenous opioids mediate stress-induced analgesia, Claudia Sommer32. The first crystal structure of an iGluR ligand-binding core, Ke Ren Ronald Dubner33. Control of pain initiation by endogenous cannabinoids, Andrea Hohmann34. Peripheral Analgesia involves Cannabinoid Receptors, Julie Desroches35. Glia: a new pain target, Marzia Malcangio36. The challenges of animal models of pain, Bradley Kerr and Muhammad Saad Yousuf37. Mechanisms of bone cancer pain, Philippe Sarret38. Molecular Structure of the Mu-Opioid Receptor, Roger Knaggs39. Milestone Effect of DNIC in our Understanding of Pain, Serge Marchand40. Original description of central sensitisation, Sheila Black41. Molecular basis for Placebo effect, Lesley BromleySection 3: Science42. Early discussions on an mechanistic approach to pain, Robert D. Searle43. Plasticity: a key concept in pain, Alfredo Ribeiro and Da Silva Claire Magnussen44. The importance of descending modulatory pain systems, Enrique Collantes45. Nocebo and its importance in clinical practice, Helen Laycock46. Mechanisms of Action of Acetaminophen for Pain Treatment, Pierre Beaulieu47. Making the link from central sensitization to clinical pain, Juergen SandkuehlerSection 4: Clinical48. Proof of concept: epidural morphine, Vicky Tidman49. The Definition of Fibromyalgia, Mike Shipley50. The advent of PCA for post operative analgesia, Suzanne Chapman51. Undertreatment of pain with metastatic cancer, Matthew J. Allsop and Michael Bennett52. Faces scales in paediatric pain assessment, Alison Bliss53. Epidural block and phantom limb pain, Stephan Schug54. Clarifying the concept of Breakthrough pain, Giovambattista ZeppetellaSection 5: Mechanisms55. Paediatric pain epidemiology, Alison Bliss56. Recognising the importance of HIV disease and pain, Peter Kamerman57. Fast acting fentanyl for breakthrough pain, Andrew N. Davies58. The additive analgesia of adrenaline in epidural blockade, Paul Farquhar-Smith59. What is the clinical relevance of the Likert scale for pain, Felicia Cox60. Post operative pain: assessing the standards, Jane Quinlan61. Opioid induced hyperalgesia, Kirsty Bannister62. CRPS epidemiology, Naomi Scott63. Seminal paper on epidemiology of cancer pain, Paul Farquhar-Smith64. Endoscopic ultrasound guided coeliac plexus block, Arun BhaskarSection 6: Neuropathic65. Autotomy: an early neuropathic pain model, Nicholas D. James and Elizabeth J. Bradbury66. Risk factors for post amputation pain, Tudor Phillips67. Chronic constriction injury (CCI) model of neuropathic pain, Matthew Brown68. Antineuropathic medication combination therapy, Mick G. Serpell69. RCT evidence for gabapentin in post herpetic neuralgia, Rajesh Gupta70. Identification of the target of gabapentinoid action in neuropathic pain, Turo J. Nurmikko71. Recognition of the importance of Neuropathic pain epidemiology, Matthew Brown72. Botox analgesia for neuropathic pain, Abdelghani Mowafak73. DNIC and prediction of chronic post surgical pain, Sibtain Anwar74. Pregabalin in the reduction of chronic post knee surgery chronic pain, Richard M. Langford75. Multidisciplinary Cognitive Behavioural Treatment for Chronic Pain, Toby Newton John76. Disability in Chronic Low Back Pain, Rakesh JainSection 7: Psychosocial77. The Understanding of Social Effects in Pain, Amanda WilliamsSection 8: Genetics78. Congenital insensitivity to pain, Bhagat Singh. Alban Latremoliere, and Michael Costigan79. Polymorphic CYP2D6 as the Responsible Enzyme of Activation, Ingolf Cascorbi80. COMT genotypes in pain responses, Matthew Hamilton81. The link between NaV1.7 mutation and erythromelalgia, Bradley J. Kerr82. COMT and morphine use in cancer pain, Fausto Morell-Ducos83. Pioneering use of gene therapy for pain, Roman Cregg and Biloskytsky Vadym