Lignans: Chemical, Biological and Clinical Properties

by David C. Ayres, John D. Loike

Overview

The volume surveys the chemical, biological, and clinical properties of lignans, providing information on their isolation, purification, identification and chemical synthesis. The volume also explores fully the potential use of these compounds as antitumor agents.

Product Details

ISBN-13:	9780521304214
Publisher:	Cambridge University Press
Publication date:	11/30/1990
Series:	Chemistry and Pharmacology of Natural Products
Pages:	424
Product dimensions:	6.30(w) x 9.29(h) x 1.02(d)

Table of Contents

Preface; Glossary; 1. Introduction; 2. A registry of the natural lignans; 3. Biological and clinical properties of lignans; 4. Etoposide and teniposide; 5. Isolation, purification and initial characterisation; 6. Determination of structure; 7. Biosynthesis; 8. Synthesis; References.

Editorial Reviews

"...an excellent volume in what is beginning to look as though may turn into an excellent series." Biochemical Systematics and Ecology

"...has set a very high standard for future volumes in this series, and gets full marks for giving equal priority to the three diverse areas of research activity mentioned in the title....The authors of this volume and the series editors are all to be congratulated for their part in producing a volume that will be of outstanding interest to active lignan researchers in the fields of botany, biochemistry, chemistry, oncology, pharmacognosy, and pharmacology. I heartily recommend the purchase of this volume to these groups of scientists, for whom it will quickly become indispensable." Economic Botany

"...the authors have done an excellent job in providing a comprehensive but readable text, which is highly recommended to chemists interested in natural products." Percy S. Manchand, Journal of the American Chemical Society

"This is a comprehensive review of the chemistry and pharmocology of the 440 naturally occurring lignans, with some material on the semisynthetic derivatives etoposide and teniposide which find clinical use in cancer treatment. Given the importance and ubiquity of lignans as bioactive natural products, this is a reference work which a practicing chemist cannot afford to be without." International Journal of Pharmacology International Journal of Pharmacology

From the Publisher