Liquid Chromatography: Fundamentals and Instrumentation

Liquid Chromatography: Fundamentals and Instrumentation

ISBN-10:
0124158072
ISBN-13:
9780124158078
Pub. Date:
01/25/2013
Publisher:
Elsevier Science
ISBN-10:
0124158072
ISBN-13:
9780124158078
Pub. Date:
01/25/2013
Publisher:
Elsevier Science
Liquid Chromatography: Fundamentals and Instrumentation

Liquid Chromatography: Fundamentals and Instrumentation

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Overview

A single source of authoritative information on all aspects of the practice of modern liquid chromatography suitable for advanced students and professionals working in a laboratory or managerial capacity


Product Details

ISBN-13: 9780124158078
Publisher: Elsevier Science
Publication date: 01/25/2013
Series: Handbooks in Separation Science
Pages: 520
Product dimensions: 6.20(w) x 9.10(h) x 1.00(d)

About the Author

Salvatore Fanali is Director of Research at the Institute of Chemical Methodologies, Italian National Research Council (C.N.R.) in Monterotondo (Rome), Italy, and head of the Capillary Electromigration and Chromatographic Methods Unit at the same Institute. His research activity is mainly focused on separation science including the development of modern miniaturized techniques (electrodriven and liquid chromatography). He also studies hyphenation with mass spectrometry and development of new stationary phases. Separation methods developed are currently applied to food, pharmaceuticals, chiral environment, and biomedical analysis. He is Editor of the Journal of Chromatography A and a member of the advisory editorial board of seven international scientific journals. Fanali is the author of about 300 publications including some book chapters. He received several awards including the “Liberti Medal” in Separation Science from the Italian Chemical Society.

Paul Haddad is currently a Distinguished Professor of Chemistry and Australian Research Council Federation Fellow at the University of Tasmania, as well as Director of the Pfizer Analytical Research Centre. He has more than 500 publications in this field and has presented in excess of 450 papers at local and international scientific meetings. He is an editor of Journal of Chromatography A, a contributing editor for Trends in Analytical Chemistry, and was an editor of Analytica Chimica Acta for 6 years. He is currently a member of the editorial boards of 10 other journals of analytical chemistry or separation science.

He is the recipient of several national and international awards, including the ACS Award in Chromatography, the Marcel Golay Award, the AJP Martin Gold Medal awarded by the Chromatographic Society, the Royal Society of Chemistry Analytical Separation Methods Award, the RACI HG Smith and Analytical Division medals, and more.

Professor Colin Poole is internationally known in the field of thin-layer chromatography and is an editor of the Journal of Chromatography and former editor of the Journal of Planar Chromatography – Modern TLC. He has authored several books on chromatography, recent examples being The Essence of Chromatography published by Elsevier (2003), and Gas Chromatography published by Elsevier (2012). He is the author of approximately 400 research articles, many of which deal with thin-layer chromatography, and is co-chair of the biennial “International Symposium on High-Performance Thin-Layer Chromatography”.

David Lloyd obtained his PhD from the Department of Chemistry, University of York, UK, working with Prof. David Goodall on the development of laser-based polarimetry as a chiral detection method. He then completed postdoctoral research on bioanalytical capillary electrophoresis (CE) with Prof. Irving Wainer at St. Jude Children’s Research Hospital in Memphis, TN. He has since worked both in academia (McGill University, Departments of Oncology and Experimental Medicine) and the pharmaceutical industry (DuPont Pharmaceuticals and Bristol-Myers Squibb). Whilst at McGill, Dr. Lloyd’s analytical research focused on microscale bioanalysis by CE and on chiral CE. Since moving to the pharmaceutical industry, his responsibilities have been in analytical R&D for projects ranging from the late discovery stage through worldwide registrational filings, with a primary focus on separations science. From 1995 – 2002, Dr. Lloyd was Contributing Editor of TrAC - Trends in Analytical Chemistry; and from 1999 - 2011, he was Editor of the Journal of Chromatography B.

Table of Contents

  1. Milestones in the Development of Liquid Chromatography
  2. Kinetic Theory of Liquid Chromatography
  3. Column Technology in Liquid Chromatography
  4. Reversed-phase Liquid Chromatography
  5. Secondary Chemical Equilibria in Reversed-Phase Liquid Chromatography
  6. Hydrophilic Interaction Liquid Chromatography
  7. Hydrophobic Interaction Liquid Chromatography
  8. Liquid-Solid Chromatography
  9. Ion Chromatography
  10. Size-exclusion chromatography
  11. Solvent Selection for Liquid Chromatography
  12. Method development in Liquid Chromatography
  13. Theory and Practice of Gradient Elution Liquid Chromatography
  14. Coupled-Column Liquid Chromatography
  15. General Instrumentation
  16. Advanced Spectroscopic Detectors for Identification and Quantification: Mass Spectrometry
  17. Advanced Spectroscopic Detectors for Identification and Quantification: FTIR and Raman
  18. Advanced Spectroscopic Detectors for Identification and Quantification: Nuclear Magnetic Resonance
  19. Data Analysis Methods
  20. Quantitative Structure-Retention and Property Relationships
  21. Modeling of Preparative Liquid Chromatography
  22. Process Concepts in Preparative Liquid Chromatography
  23. Preparative Chromatography of Biopolymers
  24. Miniaturization and Microfluidics
  25. Capillary Electrochromatography

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