Macroporous Polymers: Production Properties and Biotechnological/Biomedical Applications / Edition 1

by Bo Mattiasson, Ashok Kumar, Igor Yu. Galeaev

Overview

Macroporous polymers are rapidly becoming the material of choice for many tissue engineering, bioseparation, and bioprocessing applications. However, while important information is scattered about in many different publications, none, to date, have drawn this information together in user-friendly format, until now. Meeting the need for an accessible, organized resource, Macroporous Polymers: Production Properties and Biotechnological/Biomedical Applications supplies a systematic presentation of the production, characterization, and application of these polymers.

The text discusses traditional methods of production, including phase separation polymerization, leaching, foaming, and double emulsion as well as emerging methods such as cryogelation. The chapters also detail the various applications of macroporous gels for the separation of biomolecules and for the cultivation of mammalian cells in bioreactors and for tissue engineering. The book underscores existing and potential problems while providing a solid background on which to base the evaluation of the scientific and commercial value of new developments.

The editors bring together different viewpoints, summarize state-of-the-art achievement, and cover applications in biotechnology, downstream processing, and biomedicine. They have collected the latest research and molded it into a cohesive reference, closing the gap between macromolecular design and production of these gels/polymers and their possible applications. With the intensity of development in this area likely to increase, the foundation provided by this book can help you meet the challenges inherent in the development of new and better materials for new and better applications.

Product Details

ISBN-13:	9781420084610
Publisher:	Taylor & Francis
Publication date:	12/23/2009
Pages:	530
Product dimensions:	6.12(w) x 9.19(h) x (d)

About the Author

Bo Mattiasson, Ashok Kumar, Igor Yu. Galeaev

Table of Contents

Introduction vii

Contributors ix

Section I Production of Macroporous Polymers

1 Production of Macroporous Polymeric Materials by Phase Separation Polymerization Oguz Okay 3

2 Production and Properties of Cryogels by Radical Polymerization Fatima M. Plieva Igor Yu. Galaev Bo Mattiasson 23

3 Macroporous Polymer Scaffolds through Leaching Processes Michael C. Hacker Kristina Ambrosch Michaela Schulz-Siegmund 49

4 Production and Properties of Poly(Vinyl Alcohol) Cryogels: Recent Developments María C. Gutiérrez Inmaculada Aranaz Maria L. Ferrer Francisco del Monte 83

5 Preparation of Polylactide Scaffolds Ming-Hua Ho Da-Ming Wang Hsyue-Jen Hsieh Juin-Yih Lai 117

6 Macroporous Polysaccharide Gels Fatima M. Plieva Igor Yu. Galaev Bo Mattiasson 131

7 Superporous Agarose Gels: Production, Properties, and Applications Per-Erik Gustavsson Peter Tiainen Per-Olof Larsson 155

8 Fast-Responsive Macroporous Hydrogels Hossein Omidian Kinam Park 179

Section II Characterization of Macroporous Polymers

9 Characterization of Macroporous Gels Irina N. Savina Paul E. Tomlins Sergey V. Mikhalovsky Igor Yu. Galaev 211

10 Macroporous Polymeric Materials: Synthetic Strategies and Morphological Characterizations Anil K. Bajpai Sandeep K. Shukla 237

Section III Application of Macroporous Polymers

11 Macroporous Gels for Isolation of Small Molecules from the Solutions Containing Suspended Material Bo Mattiasson Fatima M. Plieva Igor Yu. Galaev 267

12 Monolithic Macroporous Polymers as Chromatographic Matrices Nika Lendero Krajnc Franc Smrekar Vida Frankovic Aleš Štrancar Aleš Podgornik 291

13 Chromatographic Separation of Plasmid DNA Using Macroporous Beads Duarte M. de França Prazeres 335

14 Cryogels as Matrices for Cell Separation and Cell Cultivation Maria B. Dainiak Ashok Kumar Igor Yu. Galaev Bo Mattiasson 363

15 Macroporous Polymeric Scaffolds for Tissue Engineering Applications Ashok Kumar Era Jain Akshay Srivastava 405

16 Polymeric Scaffolds for Regenerative Medicine Paul A. De Bank Matthew D. Jones Marianne J. Ellis 467

Index 497