Mass Spectrometry of Biological Materials / Edition 2

by Barbara S. Larsen, Charles N. McEwen

Overview

Second Edition provides up-to-the-minute discussions on the application of mass spectrometry to the biological sciences. Shows how and why experiments are performed and furnishes details to facilitate duplication of results.

Product Details

ISBN-13:	9780824701574
Publisher:	Taylor & Francis
Publication date:	03/02/1998
Edition description:	REV
Pages:	486
Product dimensions:	6.00(w) x 9.00(h) x (d)

About the Author

Barbara S. Larsen, Charles N. McEwen

Table of Contents

Instrumentation and ionization methods for the analysis of biological materials by mass spectrometry; high resolution mass spectrometry and accurate mass measurements of biopolymers using MALDI-TOF; a novel geometry mass spectrometer, the quadrupole orthogonal acceleration time-of-flight instrument, for low femtomole/attomole range biopolymer sequencing; affinity techniques combined with mass spectrometry; screening molecular diversity using pulsed ultrafiltration mass spectrometry; mass spectrometry in immunology - identification of a minor histocompatibility antigen; strategies for the rapid characterization of recombinant and native proteins by mass spectrometry; mass spectrometry in drug discovery; analysis of glycoproteins; analysis of phosphorylated protein by mass spectrometry; mass spectrometry-based approaches towards the study of regulated biological systems; gels in vacuo? a minimalist approach for combining mass spectrometry and polyacrylamide gel electrophoresis; studying noncovalent interactions by electrospray ionization mass spectrometry; protein-protein and protein-ligand interactions studied by hydrogen/deuterium exchange electrospray mass spectrometry; characterization of oligonucleotides by electrospray mass spectrometry; methods and applications of sizing DNA by matrix-assisted laser desorption/ionization mass spectrometry; network-based bioinformatics in protein mass spectrometry.