Molecular Genetics, Gene Transfer, and Therapy / Edition 1

by W. Jean Dodds, James E. Womack

Overview

Animal science is being transformed by advances in molecular genetics. This book covers this exciting transformation. Both the diagnosis and treatment of disease are discussed in seven chapters by a team of leading international authorities. From oncogenesis and hemophilia to retroviral virulence and genome mapping, this volume yields an understanding of fundamental mechanisms of action and insightful means of diagnosis and treatment. Practicing veterinarians and researchers in animal science will find this book useful.

Product Details

ISBN-13:	9780120392414
Publisher:	Elsevier Science
Publication date:	08/18/1997
Series:	Advances in Veterinary Medicine , #40
Pages:	227
Product dimensions:	6.00(w) x 9.00(h) x (d)

About the Author

W. Jean Dodds received her D.V.M. in 1964 from the Ontario Veterinary College. From 1965 to 1986 she worked for the New York State Health Department in Albany, where she conducted comparative studies of animals with inherited and acquired bleeding diseases. She also was a member of many national and international committees on hematology, animal models of human disease, veterinary medicine, and laboratory animal science. Dodds was a grantee of the National Heart, Lung, and Blood Institute (NIH) and has over 150 research publications. She was formerly President of the Scientist’s Center for Animal Welfare; Chairman of the Committee of Veterinary Medical Sciences; and Vice-Chairman of the Institute of Laboratory Animal Resources, National Academy of Sciences. In 1974, Dodds was selected as Outstanding Woman Veterinarian of the Year by the AVMA, Denver, Colorado; in 1977, she received the Region I Award for Outstanding Service to the Veterinary Profession from the American Animal Hospital Association, Cherry Hill, New Jersey; Dodds received the Gaines Fido Award as Dogdom’s Woman of the Year in 1978 and 1990; and the Award of Merit in 1978 in Recognition of Special Contributions to the Veterinary Profession from the American Hospital Association, Salt Lake City, Utah. In 1984 she was awarded the Centennial Medal from the University of Pennsylvania School of Veterinary Medicine.Dodds moved to Southern California in 1986 to establish Hemopet, the first nonprofit national blood bank program for animals. In 1987 she was elected a distinguished Practitioner of the National Academy of Practice in Veterinary Medicine. Currently, Dodds is actively expanding Hemopet’s full-service, nonprofit animal blood bank program, which provides canine blood components, blood bank supplies, and related services throughout North America. Dodds is a member of numerous professional societies and she consults in clinical pathology and lectures nationwide to veterinarians and dog fanciers on hem

Table of Contents

J.G. Hauge, Historical Overview and Current Trends.
J. Carter, S. Vande Woude, and G.F. Vande Woude, Mechanisms of Oncogenesis.
G.H. Sack, Jr., Molecular Genetics in the Diagnosis of Canine Disease.
J. Walter and K.A. High, Gene Therapy for the Hemophilias.
F. Fuller, Genes Controlling Retroviral Virulence.
J.E. Womack, Mapping Genomes of Domestic Animals.
C.S. Mellersh and E.A. Ostrander, The Canine Genome.
Subject Index.

Editorial Reviews

Reviewer: Barbara E. Kitchell, DVM (University of Illinois College of Veterinary Medicine)
Description: This book presents an overview of molecular genetics and the development of genomics and gene therapy, structured as a series of review articles of a variety of topics for which veterinary data or applicability are most advanced.
Purpose: The editors seek to provide an overview and perspectives on the rapid-paced and ethically intriguing field of molecular genetics as it applies to veterinary medicine. These objectives are worthy and very much needed. The editors do a credible job explaining a very extensive and still-expanding literature.
Audience: The editors do not state their intended audience, but the tone and depth of these review chapters suggest the audience should be beyond the general practitioner level. I feel this volume is particularly useful for residents, graduate students, and academics involved in genetics, virology, and oncologic, hematologic, and internal medicine specialties. The editors have assembled a very impressive group of contributors, all of whom have contributed significantly to their respective fields.
Features: The line drawings in the book are extremely helpful in conveying abstract concepts to readers new to the field. The references are extensive and very current. The index and table of contents are adequate. The book is nicely arranged and is of appropriate size to be a reference. No unique features are present.
Assessment: This book is a useful overview of an exciting, expanding field of science. Molecular genetics is essential to modern medicine, and the veterinary student, academic, and researcher would all greatly benefit from an understanding of the contents of this book.

Doody's Review Service

Reviewer: Barbara E. Kitchell, DVM (University of Illinois College of Veterinary Medicine)
Description: This book presents an overview of molecular genetics and the development of genomics and gene therapy, structured as a series of review articles of a variety of topics for which veterinary data or applicability are most advanced.
Purpose: The editors seek to provide an overview and perspectives on the rapid-paced and ethically intriguing field of molecular genetics as it applies to veterinary medicine. These objectives are worthy and very much needed. The editors do a credible job explaining a very extensive and still-expanding literature.
Audience: The editors do not state their intended audience, but the tone and depth of these review chapters suggest the audience should be beyond the general practitioner level. I feel this volume is particularly useful for residents, graduate students, and academics involved in genetics, virology, and oncologic, hematologic, and internal medicine specialties. The editors have assembled a very impressive group of contributors, all of whom have contributed significantly to their respective fields.
Features: The line drawings in the book are extremely helpful in conveying abstract concepts to readers new to the field. The references are extensive and very current. The index and table of contents are adequate. The book is nicely arranged and is of appropriate size to be a reference. No unique features are present.
Assessment: This book is a useful overview of an exciting, expanding field of science. Molecular genetics is essential to modern medicine, and the veterinary student, academic, and researcher would all greatly benefit from an understanding of the contents of this book.

This book presents an overview of molecular genetics and the development of genomics and gene therapy, structured as a series of review articles of a variety of topics for which veterinary data or applicability are most advanced. The editors seek to provide an overview and perspectives on the rapid-paced and ethically intriguing field of molecular genetics as it applies to veterinary medicine. These objectives are worthy and very much needed. The editors do a credible job explaining a very extensive and still-expanding literature. The editors do not state their intended audience, but the tone and depth of these review chapters suggest the audience should be beyond the general practitioner level. I feel this volume is particularly useful for residents, graduate students, and academics involved in genetics, virology, and oncologic, hematologic, and internal medicine specialties. The editors have assembled a very impressive group of contributors, all of whom have contributed significantly to their respective fields. The line drawings in the book are extremely helpful in conveying abstract concepts to readers new to the field. The references are extensive and very current. The index and table of contents are adequate. The book is nicely arranged and is of appropriate size to be a reference. No unique features are present. This book is a useful overview of an exciting, expanding field of science. Molecular genetics is essential to modern medicine, and the veterinary student, academic, and researcher would all greatly benefit from an understanding of the contents of this book.

Barbara E. Kitchell