Neural Stem Cells: Development and Transplantation / Edition 1

by Jane E. Bottenstein

Overview

Neural Stem Cells: Development and Transplantation provides comprehensive, critical and insightful reviews by leading experts in this exciting field of research. This volume will provide the latest data on neural stem cell properties and their therapeutic applications.

This volume will be particularly useful for students, basic scientists, and clinicians in the academic or industrial sectors who have an interest in understanding neural development and its application to repairing the nervous system.

Product Details

ISBN-13:	9781402075889
Publisher:	Springer US
Publication date:	11/30/2003
Edition description:	2003
Pages:	473
Product dimensions:	6.06(w) x 9.25(h) x 0.05(d)

Table of Contents

Neural Stem Cell Models of Development and Disease.- Neural Stem and Progenitor Cells: Lineage and Cell Fate Determination.- Stage-Specific and Cell Fate Markers.- Isolation of Stem Cells from Multiple Sites in the CNS.- Neural Cells Derived From Embryonic Stem Cells.- On the Origin of Newly Made Neural Cells in the Adult Organism: Does Transdifferentiation Occur?.- Neural Stem Cell Purification and Clonal Analysis.- Embryonic and Neural Stem Cell Lines.- Isolation, Survival, Proliferation, and Differentiation of Human Neural Stem Cells.- Neuronal Replacement by Transplantation.- Derivation of Myelin-forming Cells for Transplantation Repair of the CNS.- Induction of Adult Cortical Neurogenesis From Neural Precursors In Situ.- Neural Stem Cells for Cellular Therapy in Humans.- Genetic Modification of Neural Stem/Progenitor Cells.

Editorial Reviews

Reviewer: Celso Agner, MD, MS, MSc (Michigan Neurology Partners)
Description: Stem cell research has been influencing the development of neuroscience ever since its discovery, in particular for the possible use of stem cells in the management of degenerative diseases of the nervous system. A book on its applications is very welcome in the field.
Purpose: The purpose of this book is to address the development of stem cells and the current potential application for the treatment of neurological conditions. These worthy objectives are fully met by the authors.
Audience: Neurologists and neurosurgeons are the main audiences for this book.
Features: The most important aspect of this book is the progression of topics from identification of stem cells in different areas of the body to the potential transplantation for the management of degenerative diseases such as Parkinson's and others. The illustrations are well done and correlate well with the written text. In my view, one of the major shortcomings is the absence of sections related to the survival of stem cells in the host organ and the current possibility of clinical applications. Overall, however, the book is of very good quality.
Assessment: This is an important book for neurologists, neurosurgeons, and neurophysiologists interested in the study and applications of stem cells in health and disease.

Doody's Review Service

3 Stars from Doody