Neurochemistry of Abused Drugs

by Steven B. Karch, MD, FFFLM (Editor)

Overview

Extracted from the Drug Abuse Handbook, 2^nd edition, to give you just the information you need at an affordable price.

Beginning with a detailed look at individual drugs and their effects on the brain, Neurochemistry of Abused Drugs considers the changes in neurotransmitter levels and discusses the relationship of these changes to the nature and phenomenon of addiction. New studies highlight the addictive capacity of nicotine as well as introduce novel compounds that may aid in tobacco cessation. Chapters examine nicotine dependant neuroplasticity and the various neurochemical substrates that support and promote addiction including cholinergic, dopaminergic, and GABAergic adaptations. The book also offers detailed information on the neurochemical and neurobehavioral consequences of MDMA, methamphetamine, and cocaine use. Recent discoveries on the neurotransmitter systems involved in each of these drugs reveal new therapeutic targets for alleviating addiction including ibogaine, and GABA and glutamate receptors.  Extensively referenced and citing numerous up-to-date studies, this book provides unparalleled insight into the action and potential inhibition of drugs of abuse.

Product Details

ISBN-13:	9781420054415
Publisher:	Taylor & Francis
Publication date:	10/09/2007
Pages:	162
Product dimensions:	7.00(w) x 10.00(h) x (d)

About the Author

Steven B. Karch MD, FFFLM

Table of Contents

The Dopamine Transporter and Addiction, Neurochemistry of Nicotine Dependence, Neurochemical Substrates of Habitual Tobacco Smoking, Neurochemical and Neurobehavioral Consequences of Methamphetamine Abuse, Neurochemical Adaptations and Cocaine Dependence, Neuropsychiatric Consequences of Chronic Cocaine Abuse, Neurobiology of 3,4-Methylenedioxymethamphetamine (MDMA, or “Ecstasy”), Index