Pharmaceutical Production Facilities: Design and Applications: Design and Applications / Edition 2

by Cole

Overview

Pharmaceutical Production Facilities: Design and Applications considers the concepts and constraints that have to be considered in the design of small, medium and large scale production plants. The layout, along with the flow of materials and personnel through facilities are considered with reference to ensuring compliance with current good manufacturing practice. The book explains how clean rooms have developed, and how recent regulations affect their design. The latest concepts for reducing contamination levels from the operator and the product are discussed. It assess current changes in standards and quality control and makes suggestions for the "ideal production environment" to enable standards to be validated to current standards.

Product Details

ISBN-13:	9780367400620
Publisher:	Taylor & Francis
Publication date:	09/23/2019
Edition description:	2nd ed.
Pages:	344
Product dimensions:	7.00(w) x 10.00(h) x (d)

Table of Contents

Contributors vi

Preface vii

1 Introduction 1

2 Project Design and Management 7

3 Site Selection 25

4 Process Flow 29

5 Pharmaceutical Process Utility Systems 47

6 Considerations in the Design of a Pharmaceutical Facility 63

7 Cleanrooms 91

8 Tablet Production Systems 125

9 Tablet Coating Systems 145

10 Capsule Filling Systems 175

11 The Design of a Sterile and Aseptic Manufacturing Facility 197

12 Special Production Systems 223

13 Flexible Manufacturing Systems and Automation 245

14 Packaging Systems 293

15 Validation 297

Index 329

Editorial Reviews

An enlarged and revised edition (first, 1990) providing a thorough introduction to the design of pharmaceutical secondary manufacturing facilities, illustrating many of the concepts and constraints to be considered in the design of small, medium, and large scale production plants. Covers project design and management; site selection; process flow; pharmaceutical process utility systems; considerations in the design of a pharmaceutical facility; cleanrooms; tablet production systems; tablet coating systems; capsule filling systems; the design of a sterile and aseptic manufacturing facility; special production systems; flexible manufacturing systems and automation; packaging systems; and validation. Annotation c. by Book News, Inc., Portland, Or.

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