Practical Differential Diagnosis in Surgical Neuropathology / Edition 1

by Richard A. Prayson, Mark L. Cohen

Overview

Not another textbook for neuropathology! Yes, Our publishers helped us with this last problem by we hear you and feel your pain. In fact, that was our insisting on black and white photographs. We ini­ initial response when we were approached to write tially protested, noting that many recent textbook the book you are now holding. In surveying the reviews seemed to be primarily guided by whether expanse of currently available neuropathology illustrations were in color (good) or black and white textbooks, however, we came to feel that there was (bad). However, upon further reflection we accepted a place for a book that could combine our career this mandate as a blessing in disguise, allowing the experiences of trying to discern what is known (and reader to focus on differences in morphology, rather knowable) with the perennially proposed question, than tincture, as a guide to correct diagnosis. In fact, "What do we need to know?" Together we tried to one of us (M. e. ) has always been a fan of black and produce a book that would be practical, understand­ white photography, both in histologic atlases as well able, and to the point (minimizing reading time as in the immortal photographs of artists ranging from during intraoperative consultation). We have con­ Ansel Adams to Diane Arbus.

Product Details

ISBN-13:	9781617372018
Publisher:	Springer-Verlag New York, LLC
Publication date:	11/05/2010
Edition description:	Softcover reprint of hardcover 1st ed. 2000
Pages:	179
Product dimensions:	8.27(w) x 10.98(h) x 0.02(d)

About the Author

Prayson, Richard A., MD (Cleveland Clinic Foundation); Cohen, Mark L., MD (Case Western Reserve University)

Table of Contents

1 Intraoperative Consultation.- 2 Gliosis.- 3 Fibrillary Astrocytoma.- 4 Low-Grade Astrocytoma Variants.- 5 High-Grade Astrocytoma Variants.- 6 Radiation Change.- 7 Pilocytic Astrocytoma.- 8 Pleomorphic Xanthoastrocytoma.- 9 Subependymal Giant Cell Astrocytoma.- 10 Oligodendroglioma.- 11 Mixed Gliomas.- 12 Ependymoma.- 13 Subependymoma.- 14 Myxopapillary Ependymoma.- 15 Central Neurocytoma.- 16 Dysembryoplastic Neuroepithelial Tumor.- 17 Ganglioglioma and Ganglion Cell Tumors.- 18 Choroid Plexus Tumors.- 19 Meningioma.- 20 Meningeal Sarcoma.- 21 Hemangioblastoma.- 22 Central Nervous System Primitive Neuroectodermal Tumors.- 23 Pineal Region Tumors.- 24 Pituitary Gland Lesions.- 25 Primary Central Nervous System Lymphoma.- 26 Schwannoma.- 27 Benign Epithelial Lesions—Craniopharyngiomas and Cysts.- 28 Melanocytic Lesions.- 29 Paraganglioma.- 30 Chordoma.- 31 Tumor-Like Demyelinating Lesion.- 32 Vascular Malformations.- 33 Central Nervous System Vasculitis.- 34 Granulomatous Inflammation.- 35 Meningitis, Abscess, and Encephalitis.

Editorial Reviews

" The chapter on tumor-like demyelinating lesions and their distinction from astrocytomas is especially important.... The main value of the book is the quick access to brain tumor illustrations and text. It will appeal to residents and fellows in neuropathology."__Journal of the Neurological Sciences.

" The text is surprisingly easy to read...any surgical pathologist would enjoy the natural flow of information given...they cover almost all neoplasms in the neuraxis and several important inflammatory diseases. In addition to the popular grading systems of diffuse fibrillary astrocytomas, specific variants of astrocytomas are delineated. The responsiveness to chemotherapy of oligodendrogliomas ( well differentiated or anaplastic) and mixed oligoastrocytomas is emphasized. Important mimics of neoplasm, such as multiple sclerosis and radiation necrosis, are discussed separately...The references in each and every chapter are relevant and quite up -to- date...This monograph contains very practical information, is very easy to read and comprehend, and is convenient to use in daily intraoperative consultation and regular sign-out ."-Doody's Health Science Book Review

"This new neuropathology text, written by two experienced and pragmatic neuropathologists, is a welcome addition and fills an important niche in our field. This book is targeted to the practicing general surgical pathologists and pathology residents. The text is concise at 171 pages, and centers on commonly encountered, rather than unusual, surgical neuropathology conditions. It is very well written, in a casual style, and the numerous asides and comments sprinkled throughout the text give the feeling that the authors are speaking directly to the reader...The book is ideally suited to have on hand in the surgical pathology suite adjacent to the operating room...General surgical pathologists will be very pleased with this new book and will be eager to add it to their libraries...Experienced neuropathologists also can learn from this readable work and and the chapters on protoplasmic astrocytomas and dysembryoplastic neuroepithelial tumors are particularly informative...The book is also an ideal resource for pathology, neurosurgery, and neurology residents." -Journal of Neuropathology and Experimental Neurology

"...in spite of all the impressive insights into the molecular pathology of brain tumors, the neuropathologist's diagnosis is mainly based on the H&E features, and, of course, the immunohishemical profile. This is one of the merits of this book. In addition, the authors have a good sense of humor and often make interesting pragmatic reflections. The chapters are succinct but written in an enjoyable style....this is an enjoyable and well-written textbook on the specttrum of surgical neuropathology."-Acta Neurologica Belgica

"...would be of considerable value to more senior trainees to whom most of the diseases are already familiar to some extent, and particularly in assessing one's readiness to sit for qualifying examinations." -Pediatric and Developmental Pathology

From the Publisher

3 Stars from Doody

This book is a description of the diagnostic challenges (neoplastic and non-neoplastic) of surgical neuropathology. Both authors are very experienced in the field and they have, for the most part, succeeded in the inclusion of the most practical information needed for diagnostic consideration. The text is surprisingly easy to read despite a few obvious typographic errors, and any surgical pathologist would enjoy the natural flow of information given. Radiologists and neurosurgeons, however, may find the indispensable morphologic details difficult to follow. The authors begin with a brief introduction to intraoperative consultation, followed by 34 concise chapters of different diseases, each replete with pathology, immunohistochemistry, genetics, clinical history, radiology, differential diagnoses, treatment of choice, and prognostic implications. Most are conveniently summarized in tables. They cover almost all neoplasms in the neuraxis and several important inflammatory diseases. In addition to the popular grading systems of diffuse fibrillary astrocytomas, specific variants of astrocytomas are delineated. The responsiveness to chemotherapy of oligodendrogliomas (well differentiated or anaplastic) and mixed oligoastrocytomas is emphasized. Important mimics of neoplasm, such as multiple sclerosis and radiation necrosis, are discussed separately. Pertinent immunohistochemical findings and caveats (such as immunoreactivity of astrocytic cytoplasm to antibodies against pancytokeratins) are included whenever applicable. All the key features are displayed in photomicrographs, although pathologists and non-pathologists alike may find the black-and-white illustrations less impressivethan colored ones. The references in each and every chapter are relevant and quite up-to-date, but this approach results in a few duplicate appearances and possible waste of space. Compared with three other references in surgical neuropathology of similar size: Burger's Tumors of the Central Nervous System (AFIP); Kleihues' Pathology and Genetics: Tumors of the Nervous System (International Agency for Research on Cancer, 1997); and Moss' Intra-Operative Diagnosis of CNS Tumors (Arnold, 1997), this monograph contains very practical information, is very easy to read and comprehend, and is convenient to use in daily intraoperative consultation and regular sign-out.

Joe Ma

Prayson (anatomic pathology, Cleveland Clinic Foundation) and Cohen (pathology, Case Western Reserve U.) present a guide to the more commonly encountered diagnostic problems in surgical neuropathology. They focus on the differential diagnosis of the most common neuropathological entities encountered by general surgical pathologists. Information is provided on how to work with very small amounts of tissues, decide difficult situations where everything looks the same, and cope with inoperative calculations when time is short and sample preparations are less than ideal. Annotation c. Book News, Inc., Portland, OR (booknews.com)

Booknews

Reviewer: M. Joe Ma, M.D., Ph.D.(Associated Pathologists, Chartered)
Description: This book is a description of the diagnostic challenges (neoplastic and non-neoplastic) of surgical neuropathology.
Purpose: Both authors are very experienced in the field and they have, for the most part, succeeded in the inclusion of the most practical information needed for diagnostic consideration.
Audience: The text is surprisingly easy to read despite a few obvious typographic errors, and any surgical pathologist would enjoy the natural flow of information given. Radiologists and neurosurgeons, however, may find the indispensable morphologic details difficult to follow.
Features: The authors begin with a brief introduction to intraoperative consultation, followed by 34 concise chapters of different diseases, each replete with pathology, immunohistochemistry, genetics, clinical history, radiology, differential diagnoses, treatment of choice, and prognostic implications. Most are conveniently summarized in tables. They cover almost all neoplasms in the neuraxis and several important inflammatory diseases. In addition to the popular grading systems of diffuse fibrillary astrocytomas, specific variants of astrocytomas are delineated. The responsiveness to chemotherapy of oligodendrogliomas (well differentiated or anaplastic) and mixed oligoastrocytomas is emphasized. Important mimics of neoplasm, such as multiple sclerosis and radiation necrosis, are discussed separately. Pertinent immunohistochemical findings and caveats (such as immunoreactivity of astrocytic cytoplasm to antibodies against pancytokeratins) are included whenever applicable. All the key features are displayed in photomicrographs, although pathologists and non-pathologists alike may find the black-and-white illustrations less impressive than colored ones. The references in each and every chapter are relevant and quite up-to-date, but this approach results in a few duplicate appearances and possible waste of space.
Assessment: Compared with three other references in surgical neuropathology of similar size: Burger's Tumors of the Central Nervous System (AFIP); Kleihues' Pathology and Genetics: Tumors of the Nervous System (International Agency for Research on Cancer, 1997); and Moss' Intra-Operative Diagnosis of CNS Tumors (Arnold, 1997), this monograph contains very practical information, is very easy to read and comprehend, and is convenient to use in daily intraoperative consultation and regular sign-out.

Doody's Review Service