Rb and Tumorigenesis / Edition 1

by Maurizio Fanciulli

Overview

Rb and Tumorigenesis examines how recent advances have demonstrated the interaction of Rb with chromatin remodeling enzymes. This new title explores the potential roles of these interactions in Rb functions and provides some evidence that distinct Rb co-repressor may target different genes in different phases of the cell cycle.

Product Details

ISBN-13:	9780387321738
Publisher:	Springer US
Publication date:	03/17/2006
Series:	Medical Intelligence Unit
Edition description:	2006
Pages:	121
Product dimensions:	6.10(w) x 9.25(h) x 0.02(d)

Table of Contents

RB as a Positive Transcriptional Regulator during Epithelial Differentiation.- pRb in the Differentiation of Normal and Neoplastic Cells.- Regulation of DNA Replication by the Retinoblastoma Tumor Suppressor Protein.- New Insights into Transcriptional Regulation by Rb.- Regulation of Rb Function by Noncyclin Dependent Kinases.- Diverse Regulatory Functions of the E2F Family of Transcription Factors.- Regulation of E2F-Responsive Genes through Histone Modifications.- Emerging Roles for the Retinoblastoma Gene Family.- Rb and Cellular Differentiation.