Stem Cells: From Bench To Bedside (2nd Edition) / Edition 2

by Ariff Bongso, Eng Hin Lee, Bing Lim, Chui-yee Fong, Oliver Dreesen

Overview

Stem cell biology has drawn tremendous interest in recent years as it promises cures for a variety of incurable diseases. This book deals with the basic and clinical aspects of stem cell research and involves work on the full spectrum of stem cells isolated today. It also covers the conversion of stem cell types into a variety of useful tissues which may be used in the future for transplantation therapy. It is thus aimed at undergraduates, postgraduates, scientists, embryologists, doctors, tissue engineers and anyone who wishes to gain some insight into stem cell biology.This book is important as it is comprehensive and covers all aspects of stem cell biology, from basic research to clinical applications. It will have 33 chapters written by renowned stem cell scientists worldwide. It will be up-to-date and all the chapters include self-explanatory figures, color photographs, graphics and tables. It will be easy to read and give the reader a complete understanding and state of the art of the exciting science and its applications.

Product Details

ISBN-13:	9789814289382
Publisher:	World Scientific Publishing Company, Incorporated
Publication date:	11/09/2010
Edition description:	New Edition
Pages:	720
Product dimensions:	6.30(w) x 9.10(h) x 1.40(d)

Table of Contents

Foreword Tan Chorh Chuan v

Foreword George Q. Daley ix

Preface xiii

List of Contributors xix

Chapter 1 Human Embryonic Stem Cell Characterization: Similarities and Differences between Cell Lines and Sources Neil J. Harrison Ivana Barbaric Peter W. Andrews 1

Chapter 2 Molecular Principles Underlying Pluripotency and Differentiation of Embryonic Stem Cells Kyle M. Loh Boon Seng Soh Wai Leong Tam Bing Lim 23

Chapter 3 Differentiation of Human Embryonic Stem Cells to Cardiomyocytes Chris Denning Robert Passier Christine Mummery 87

Chapter 4 Suspension and Simulated Microgravity Cultures of Human Embryonic Stem Cells Steve K. W. Oh 113

Chapter 5 Large Scale Culture of Pluripotent Stem Cells for Therapy Mahendra Rao Mohan C. Vemuri 127

Chapter 6 Human Embryonic Stem Cell-derived Tissue Transplantation Therapy: Clinical Hurdles Kalamegam Gauthaman Chui-Yee Fong Ariff Bongso 155

Chapter 7 Challenges of Taking Embryonic Stem Cells from Bench to Clinic Patricia Tekamp-Olson Rosa M. Canet-Aviles Lila R. Collins Bettina J. Steffen Sohel Talib Alan O. Trounson 185

Chapter 8 Induced Pluripotent Stem Cells Oliver Dreesen Alan Colman 209

Chapter 9 Control of the Human Pluripotent Cell Cycle Gary S. Stein Andre van Wijnen Janet L. Stein Jane B. Lian Prachi N. Ghule Ricardo Medina Klaus Becker Martin Montecino Sayyed K. Zaidi Meng Qiao 235

Chapter 10 Uses of Umbilical Cord Blood Stem Cells Moniruddin Chowdhury Rajamanickam Baskar Li Ming Ong William Ying Khee Hwang 253

Chapter 11 Human Umbilical Cord Wharton's Jelly Stem Cells: Their Nature, Properties and Benefits Chui-Yee Fong Kalamegam Gauthaman Ariff Bongso 303

Chapter 12 Derivation of Hepatocytes from Human Umbilical Cord Lining Epithelial Stem Cells Dang Vinh Do Jeyakumar Masilamani Ivor Jun Lim Toan Thang Phan 323

Chapter 13 Fetal Mesenchymal Stem Cells Jerry K. Y. Chan Mahesh Choolani 339

Chapter 14 From Stem Cells to Neurons: Translating Basic Science into Preclinical Animal Validation Pamela Rizk Gerald Udolph 369

Chapter 15 Stem Cells of the Liver: Basic Science and Clinical Applications Susan M. L. Lim Shahriar Islam Malcolm R. Alison 409

Chapter 16 Stem Cells of the Eye Leonard P. K. Ang Hasan M. Reza Donald T. H. Tan 431

Chapter 17 Human (Skeletal) Mesenchymal Stem Cells: Basic Biology and Clinical Applications for Bone Tissue Regeneration Moustapha Kassem May Al-Nbaheen Dalia Ali Abdullah Aldahmash 457

Chapter 18 Cartilage Repair with Stem Cells Zheng Yang James HP Hui Eng Hin Lee 477

Chapter 19 Ligament and Tendon Repair with Adult Stem Cells Sambit Sahoo Hong Wei Ouyang James Cho Hong Goh 503

Chapter 20 Stem Cells in Human Skin: Basic Science and Applications Kenneth K. B. Tan E. Birgitte Lane 523

Chapter 21 Germline Differentiation from Stem Cells José Vicente Medrano Ana Isabel Marqués-Marí Carlos Simón 557

Chapter 22 Stem Cells of the Human Uterus: Derivation, Characterization and Uses of Endometrial Stem Cells Caroline E. Gargett 583

Chapter 23 Stem Cells in Cardiac Tissue Engineering Nicolas Christoforou Shaun Lim Kam W. Leong 611

Chapter 24 Stem Cell Science and Human Induced Pluripotent Stem Cells: Fine-Tuning the Ethical Issues Benjamin Capps Alastair Campbell 637

Chapter 25 Stem Cells: New Scientific Developments, Familiar Ethics Justine Burley 665

Index 685