Boxford High pranksters cause a chemistry lab to go wrong and students are forced to face something far worse than S.A.T.'s and cafeteria lunches - an infection that turns students into zombies scouring the halls for survivors. A group of unlikely companions; an artistic goth, star-athlete jock, disgruntled loner, would-be marine, sassy cheerleader, and angry Asian, set aside their homework to fend off the zombie apocalypse. As they fight through locker rooms and dance their way across the theater, they find surviving zombies may be more difficult than puberty. Now they must set aside homework and bake sale fundraisers to fend off the zombie apocalypse before the infection reaches beyond the walls of their suburban high school.
