Technical and Biological Components of Marrow Transplantation / Edition 1

by C. Dean Buckner, Reginald Clift

Overview

Technical and Biological Components of Marrow Transplantation presents up to date information on the scientific and technological advances that will extend and improve the clinical application of bone marrow transplantation.
The book includes the latest information on chronic myeloid leukemia and thalassemia; advances in supportive care: cytokines and progenitor expansion; and cord stem cell technology.
Soon more of patients will receive marrow transplants as part of the therapy for solid tumors and metabolic disease than for the treatment of hematologic disease. The contributors to this volume describe some of these applications, hinting at yet further, exciting possibilities.

Product Details

ISBN-13:	9780792333944
Publisher:	Springer US
Publication date:	08/31/1995
Series:	Cancer Treatment and Research , #76
Edition description:	1995
Pages:	382
Product dimensions:	6.10(w) x 9.25(h) x 0.24(d)

About the Author

Buckner, C. Dean (Fred Hutchinson Cancer Research Center); Clift, R. A. (Fred Hutchinson Cancer Research Center)

The contributors represent the specialties of cancer research, pediatrics, hematology, and nuclear medicine. Most are from research institutions, universities, and hospitals in the U.S., with two from Italy. Institutions prominently represented include Fred Hutchinson Cancer Research Center, Georgetown Univ, Dana Farber Cancer Institute, Aastrom Biosciences, Inc, and Univ of Minnesota.

Table of Contents

1. Marrow Transplantation for Chronic Myeloid Leukemia.- 2. Bone Marrow Transplantation in Thalassemia.- 3. High-Dose Chemotherapy and Autologous Stem Cell Transplantation for Breast Cancer.- 4. Bone Marrow Transplantation for Metabolic Diseases.- 5. Cytomegalovirus Infection in Marrow Transplantation.- 6. Marrow Transplantation from Unrelated Volunteer Donors.- 7. Peripheral Blood Stem Cell Transplantation.- 8. Umbilical Cord Blood Stem Cell Transplantation.- 9. In Vitro Expansion of Hematopoietic Cells for Clinical Application.- 10. Recombinant Hematopoietic Growth Factors in Bone Marrow Transplantation.- 11. Detection of Minimal Residual Disease.- 12. Genetic Therapy Using Bone Marrow Transplantation.- 13 Myeloablative Radiolabeled Antibody Therapy with Autologous Bone Marrow Transplantation for Relapsed B-Cell Lymphomas.- 14. Graft Versus Leukemia in Humans.- 15. Interleukin-2 in Bone Marrow Transplantation.- 16. Cellular Adoptive Immunotherapy after Bone Marrow Transplantation.

Editorial Reviews

Reviewer: Shalini Shenoy, MD (Washington University School of Medicine)
Description: This book covers various topics on bone marrow transplantation (BMT), including some indications for BMT, associated infections, growth factors, alternate methods of obtaining hematopoietic stem cells, and post transplant immunotherapy.
Purpose: Its purpose is to provide recent and up-to-date information on scientific and technologic advances in bone marrow transplantation to interested physicians and scientists. These are worthy objectives that the book for the most part met, leaving a few aspects of bone marrow transplantation relatively less explained.
Audience: The author directs the book at physicians and scientists involved with and interested in bone marrow transplants. I believe the book would be suitable for physicians/practitioners (not hematology/oncology based), residents, and scientists and technologists who have an interest in bone marrow transplantation. The authors of most chapters are well published in the area.
Features: The graphs and tables in the book are well selected and explain relevant topics well. There are extensive references of the topics covered. Additional topics referring to more common transplant indications and graft versus host disease would have enhanced the book's quality. This good-sized book is easily transported, is set with easy-to-read type, and uses simple language with good flow to make it an attractive book to possess for those requiring a quick and easy overview of bone marrow transplantation.
Assessment: This book makes excellent reading for those physicians and scientists looking for an initial introduction to bone marrow transplantation. The topics covered in each chapter are fairly well covered with information drawn from current publications. The book's main drawback is the lack of reference to the common transplant indications (leukemias other than CML) and a more detailed chapter dedicated to graft versus host disease and its presently available management. As mentioned, it is valuable for the non-hematology/oncology-based physician. It is recommended for the bookstore, for individual use, and for the medical library.

Doody's Review Service

3 Stars from Doody

This book covers various topics on bone marrow transplantation (BMT), including some indications for BMT, associated infections, growth factors, alternate methods of obtaining hematopoietic stem cells, and post transplant immunotherapy. Its purpose is to provide recent and up-to-date information on scientific and technologic advances in bone marrow transplantation to interested physicians and scientists. These are worthy objectives that the book for the most part met, leaving a few aspects of bone marrow transplantation relatively less explained. The author directs the book at physicians and scientists involved with and interested in bone marrow transplants. I believe the book would be suitable for physicians/practitioners (not hematology/oncology based), residents, and scientists and technologists who have an interest in bone marrow transplantation. The authors of most chapters are well published in the area. The graphs and tables in the book are well selected and explain relevant topics well. There are extensive references of the topics covered. Additional topics referring to more common transplant indications and graft versus host disease would have enhanced the book's quality. This good-sized book is easily transported, is set with easy-to-read type, and uses simple language with good flow to make it an attractive book to possess for those requiring a quick and easy overview of bone marrow transplantation. This book makes excellent reading for those physicians and scientists looking for an initial introduction to bone marrow transplantation. The topics covered in each chapter are fairly well covered with information drawn from current publications. The book's main drawback isthe lack of reference to the common transplant indications (leukemias other than CML) and a more detailed chapter dedicated to graft versus host disease and its presently available management. As mentioned, it is valuable for the non-hematology/oncology-based physician. It is recommended for the bookstore, for individual use, and for the medical library.

Shalini Shenoy

Contains 16 articles presenting current information regarding scientific and technological advances designed to extend and improve the clinical application of treatment usually described as bone marrow transplantation. The volume includes new information on chronic myeloid leukemia and thalassemia; advances in supportive care; cytokines and progenitor expansion; and cord stem cell technology. Several chapters also address some newer applications for marrow transplantation such as in the treatment of solid tumors and metabolic disease as well as other promising possibilities. Annotation c. Book News, Inc., Portland, OR (booknews.com)

Booknews

‘ ... exceptionally well edited, written in clear, precise prose which can be easily read over a weekend and contains sixteen chapters in all, with index. ... can be thoroughly recommended to a wide audience, from the student novice through to the veteran transplant physician, and well be a valuable acquisition to any ‘bone marrow' transplant teaching library.'
Cancer Forum, 20:4 (1996)

From the Publisher