The Behavioral Neurology of Dementia

by Bruce L. Miller (Editor), Bradley F. Boeve (Editor)

Overview

This new edition provides the latest research findings written by leading dementia experts. The authors have distilled the most valuable discoveries into clear, insightful chapters. Includes new chapters on autoimmune antibody-associated encephalopathy; chronic traumatic encephalopathy; and sleep issues in dementia.

Product Details

ISBN-13:	9781316687352
Publisher:	Cambridge University Press
Publication date:	11/17/2016
Sold by:	Barnes & Noble
Format:	eBook
File size:	17 MB
Note:	This product may take a few minutes to download.

About the Author

Bruce L. Miller works at the Memory and Aging Center in the Department of Neurology, University of California, San Francisco.
Bradley F. Boeve works at the Department of Neurology and the Center for Sleep Medicine at the Mayo Clinic, Minnesota.

Table of Contents

List of contributors vii

Section 1 Introduction 1

1 Basic clinical approaches to diagnosis Bruce L. Miller 1

2 Dementia with Lewy bodies Caroline A. Racine 7

3 Neurogenetics of dementia Huidy Shu 27

4 Frontotemporal dementia Indre V. Viskontas Bruce L. Miller 45

5 Alzheimer's disease Brandy R. Matthews Bruce L. Miller 56

6 Mental status examination Casey E. Krueger Joel H. Kramer 74

7 Neuropsychiatric features of dementia Edmond Teng Gad A. Marshall Jeffrey L. Cummings 85

8 Neuroimaging in dementia Maria Carmela Tartaglia Howard Rosen 101

9 Epidemiology and risk factors Kristine Yaffe Deborah E. Barnes 120

10 Animal models of dementia Erik D. Roberson Aimee W. Kao 131

11 Neuropathology of dementia Marcelo N. Macedo Eun-Joo Kim William W. Seeley 142

Section 2 Cognitive impairment, not demented 161

12 Cerebrovascular contributions to amnestic mild cognitive impairment Charles DeCarli Adriane Votaw Mayda Christine Wu Nordahl 161

13 Mild cognitive impairment Brendan J. Kelley Ronald C. Petersen 172

14 Mild cognitive impairment subgroups Julene K. Johnson 188

15 Early clinical features of the parkinsonian-related dementias Bradley F. Boeve 197

16 Dementia treatment Bradley F. Boeve Adam L. Boxer 213

17 Dementia and cognition in the oldest-old Kristin Kahle-Wrobleski María M. Corrada Claudia H. Kawas 254

Section 3 Slowly progressive dementias 264

18 Semantic dementia John R. Hodges R. Rhys Davies Karalyn Patterson 264

19 Progressive non-fluent aphasia Jennifer Ogar Maria Luisa Gorno-Tempini 279

20 Cognition in corticobasal degeneration and progressive supranuclear palsy Paul McMonagle Andrew Kertesz 288

21 Cognitive and behavioralabnormalities of vascular dementia Jee H. Jeong Eun-Joo Kim Sang Won Seo Duk L. Na 302

22 CADASIL: a genetic model of arteriolar degeneration, white matter injury and dementia in later life Stephen Salloway Thea Brennan-Krohn Stephen Correia Michelle Mellion Suzanne delaMonte 329

Section 4 Rapidly progressive dementias 345

23 Prion disorders and other rapidly progressive dementias Michael D. Geschwind Aissa Haman Indre V. Viskontas 345

24 Delirium masquerading as dementia S. Andrew Josephson 367

25 Paraneoplastic disorders of the memory and cognition Luis Bataller Josep Dalmau 377

Index 395

Editorial Reviews

Reviewer: Bryan Woodruff, MD (Mayo Clinic Arizona)
Description: This comprehensive overview of the various dementia syndromes includes practical information on clinical management as well as current research trends.
Purpose: It describes a modern approach to the evaluation of not only common causes of dementia such as Alzheimer's disease and Parkinsonian disorders, but also the less common entities such as Creutzfeldt-Jakob disease and dementia mimics. The introductory section also covers important basic neuroscience approaches to dementia, including neurogenetics, neuroimaging, neuropathology, and epidemiology. Including such diverse topics in a single book is a worthy goal, and the authors succeed while maintaining a cohesive theme throughout.
Audience: According to the authors, the book is designed to be a guide "to both the novice and expert" in dementia. Though many chapters provide straightforward information useful to nonspecialists caring for dementia patients, certain sections are somewhat technically dense and less practical, though certainly of interest to experts in the field. The authors are esteemed leaders in the field of dementia care and research.
Features: The book comprehensively covers the major dementia syndromes, including Alzheimer's disease, Parkinsonian disorders (dementia with Lewy bodies, Parkinson's disease with dementia, progressive supranuclear palsy, and corticobasal degeneration), vascular dementia, subtypes of frontotemporal dementia including the progressive aphasias, and rare forms of dementia such as Creutzfeldt-Jakob disease. The prodromal phase of dementia, mild cognitive impairment, is also covered, as are the active areas of research in the field of dementia such as neuroimaging techniques as well as neurogenetics and animal model approaches to identify more effective therapies for dementia. The chapters on neurogenetics, neuroimaging, and neuropathology are particularly informative, covering complex topics in an approachable fashion. Organizing the book into chapters on certain disorders or aspects of assessment allows readers to quickly find areas of interest, but unfortunately introduces some redundancy. However, the order of the chapters is somewhat atypical — novices in dementia would likely prefer to see high-yield topics such as mild cognitive impairment and Alzheimer's disease early in the book, but the introductory chapter is followed instead by a chapter on dementia with Lewy bodies and then a review of the neurogenetics of dementia.
Assessment: This is an authoritative and comprehensive review of topics for clinicians seeing patients with both common and rare presentations of dementia. Though the organization of the book could be better and there is some repetition, overall this is a valuable clinical resource. Topics often neglected in behavioral neurology books are covered here, such as the later chapters reviewing dementia mimics and the recognition and management of delirium.

Doody's Review Service

‘The Behavioral Neurology of Dementia is a detailed, comprehensive, reference book for doctors involved in the clinical diagnosis of dementia particularly the rarer forms and sub-types of dementia and would be particularly helpful for old age psychiatrists and neurologists. I found this book particularly useful, as an old age psychiatrist with a special interest in young onset dementia particularly the descriptions about some of the rarer types of dementia (e.g. CADSIL), rarer subtypes of common dementias (logopenic subtypes) and the encephlopathies. I will definitely be using the book when I need more information about less common presentations in dementia.’ British Medical Association Programme and Award Winners 2017

From the Publisher