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The Human Hypothalamus in Health and Disease
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The Human Hypothalamus in Health and Disease
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Product Details
ISBN-13: | 9780080862187 |
---|---|
Publisher: | Elsevier Science |
Publication date: | 11/02/1992 |
Series: | ISSN , #93 |
Sold by: | Barnes & Noble |
Format: | eBook |
Pages: | 478 |
File size: | 16 MB |
Note: | This product may take a few minutes to download. |
About the Author
Dick Swaab (1944) earned his medical and doctoral degrees at the University of Amsterdam, where he became involved in brain research during his third year of medical school. He was Director of the Netherlands Institute for Brain Research from 1978 to 2005. Since 1979 he is Professor of Neurobiology at the Medical Faculty, University of Amsterdam.
In 1985, Dr. Swaab founded the Netherlands Brain Bank (NBB) to serve as a source of clinically and neuropathologically well-documented research tissue. Since its founding, the Brain Bank has provided samples from more than 4,000 autopsies to 500 research groups in 25 countries. He was director of the NBB until 2005.
He is Leader Research team Neuropsychiatric Disorders, Neth. Inst for Neuroscience, an institute of the Royal Netherlands Academy of Arts and Sciences (KNAW). Swaab is also appointed for 2011-2017 Chao Kuang Piu Chair of Zhejiang University, Hangzhou, P.R. China.
His major research interests focus on, sexual differentiation of the human brain in relation to gender identity and sexual orientation, aging of the brain, Alzheimer’s disease, the neurobiological basis of depression, suicide and eating disorders. He has published over 540 papers in SCI journals, authored more than 200 chapters in books, and edited more than 60 books. Swaab mentored 84 PhD students from which 16 are now full professor. He is “Companion in the Order of the Dutch Lion, bestowed by her Royal Majesty Queen Beatrix of the Netherlands. In 2008 Swaab obtained the Academy medal for his role in national and international neuroscience.
Dick Swaab is author of the 2 volume monograph The Human Hypothalamus that appeared in the Handbook of Clinical Neurology series, Elsevier, Amsterdam (1000 pp) and the Dutch best seller We are our Brains (450.000 copies sold), that is translated in 14 languages. A children's version of the book (You are your brains) has also appeared in Dutch in 2013 and Russian (2014). Swaab's H-factor is 76.
Michel A. Hofman is at Netherlands Institute for Neuroscience, Netherlands
Table of Contents
Recent volumes in Progress in Brain Research
List of Contributors
Preface
Acknowledgements
Section I - Structure of the Human Hypothalamus
Chapter 1: Anatomy of the human hypothalamus (chiasmatic and tuberal region)
Section II - Clinical Manifestations of Hypothalamic Diseases
Chapter 2: Endocrine functions of the hypothalamus and alterations in neuroendocrine function – focus on thyrotropin and growth hormone
Chapter 3: Neurologic manifestations of hypothalamic disease
Section III - Technical Potentialities and Pitfalls in the Use of Human Material
Chapter 4: In situ hybridization histochemistry in the human hypothalamus
Chapter 5: Receptor localization in the human hypothalamus
Chapter 6: Human hypothalamic and pituitary neuroendocrine function during in vitro perifusion
Chapter 7: Brain banking and the human hypothalamus – factors to match for, pitfalls and potentials
Section IV - Biological Rhythms
The fourth C.U. Ariëns Kappers lecture
Chapter 8: The organization of the human circadian timing system
Chapter 9: Pre-natal development of a hypothalamic biological clock
Chapter 10: The human hypothalamus: comparative morphometry and photoperiodic influences
Chapter 11: Circadian rhythms and the suprachiasmatic nucleus in perinatal development, aging and Alzheimer’s disease
Section V - Development, Aging and Dementia
Chapter 12: Ontogeny of peptides in human hypothalamus in relation to sudden infant death syndrome (SIDS)
Chapter 13: LHRH neurons: functions and development
Chapter 14: The human hypothalamus in relation to gender and sexual orientation
Chapter 15: Hormonal influences on morphology and neuropeptide gene expression in the infundibular nucleus of postmenopausal women
Chapter 16: The human hypothalamo-neurohypophyseal system in relation to development, aging and Alzheimer's disease
Chapter 17: The hypothalamic lateral tuberal nucleus: normal anatomy and changes in neurological diseases
Chapter 18: Galanin tuberomammillary neurons in the hypothalamus in Alzheimer's and Parkinson's diseases
Section VI – Osmoregulation
Chapter 19: Animal models for osmoregulatory disturbances
Chapter 20: Autoimmune hypothalamic diabetes insipidus (autoimmune hypothalamitis)
Chapter 21: The molecular biology of human hereditary central diabetes insipidus
Chapter 22: The use of linkage analysis and the Centre d'Etude Polymorphisme Humain (CEPH) panel of DNA in the study of the arginine vasopressin, oxytocin and prodynorphin gene loci
Section VII - Hypothalamus and Reproduction
Chapter 23: Animal models for brain and pituitary gonadal disturbances
Chapter 24: Genetic, hypothalamic and endocrine features of clinical and experimental obesity
Chapter 25: Hypothalamic involvement in sexuality and hostility: comparative psychological aspects
Section VIII - Hypothalamus and Stress
Chapter 26: Re-examination of the glucocorticoid hypothesis of stress and aging
Chapter 27: The role of corticotropin-releasing hormone in the pathogenesis of Cushing's disease, anorexia nervosa, alcoholism, affective disorders and dementia
Chapter 28: Endogenous pyrogens in the CNS: role in the febrile response
Section IX - Psychiatric Diseases
Chapter 29: Endorphins and schizophrenia
Chapter 30: Neurohypophyseal peptides and psychopathology
Subject Index