The Mesencephalic Trigeminal Nucleus in the Cat / Edition 1

by N.E. Lazarov

Overview

The book summarizes our current understanding of the ultrastructure and synaptic organization of the mesencephalic trigeminal nucleus (MTN) in the cat as well as the neurochemistry of its neuronal population. Particular emphasis is given to the survey of synaptic connections and the possible physiological involvement of MTN inputs in the transmission of proprioceptive information. Using immunocyhemistry and in situ hybridization hishemistry we have identified distinct neuronal, partly chemically coded MTN subpopulations - large glutamatergic and smaller GABAergic neurons. We also show that MTN receive catecholaminergic and peptidergic innervation. The levels of transmitter substances vary according to the environmental conditions thus implying the neurochemical plasticity of MTN neurons.

Product Details

ISBN-13:	9783540665243
Publisher:	Springer Berlin Heidelberg
Publication date:	02/03/2000
Series:	Advances in Anatomy, Embryology and Cell Biology , #153
Edition description:	2000
Pages:	103
Product dimensions:	6.10(w) x 9.25(h) x 0.01(d)

Table of Contents

1 Introduction.- 2 Materials and Methods.- 2.1. Animals.- 2.2 Electron Microscopy.- 2.3 Immunocyhemical Experiments.- 2.4 In Situ Hybridization Hishemistry.- 2.5. Peripheral Nerve Axotomy.- 2.6 Data and Image Analysis.- 3 Results.- 3.1 Normal Morphology of the Mesencephalic Trigeminal Nucleus.- 3.2 Neurochemistry of the Mesencephalic Trigeminal Nucleus.- 4 Discussion.- 4.1 Structural and Synaptic Organization of the Mesencephalic Trigeminal Nucleus.- 4.2 Connections of the Mesencephalic Trigeminal Nucleus.- 4.3 Neurochemistry of the Mesencephalic Trigeminal Nucleus.- 4.4 Neurochemical Plasticity of Mesencephalic Trigeminal Nucleus Neurons.- 4.5 Functional Considerations.- 4.6 Conclusions and Future Directions.- 5 Summary.- References.