The Microbial Models of Molecular Biology: From Genes to Genomes

by Rowland H. Davis

Overview

This book explains the role of simple biological model systems in the growth of molecular biology. Essentially the whole history of molecular biology is presented here, tracing the work in bacteriophages in E. coli, the role of other prokaryotic systems, and also the protozoan and algal models - Paramecium and Chlamydomonas, primarily - and the move into eukaryotes with the fungal systems - Neurospora, Aspergillus and yeast. Each model was selected for its appropriateness for asking a given class of questions, and each spawned its own community of investigators. Some individuals made the transition to a new model over time, and remnant communities of investigators continue to pursue questions in all these models, as the cutting edge of molecular biological research flowed onward from model to model, and onward into higher organisms and, ultimately, mouse and man.

Product Details

ISBN-13:	9780195154368
Publisher:	Oxford University Press
Publication date:	09/11/2003
Pages:	352
Product dimensions:	6.38(w) x 9.50(h) x 0.97(d)

About the Author

University of California, Irvine

Table of Contents

1. Model systems, model organisms2. Morgan's progeny3. Neurospora4. Aspergillus5. Yeast6. Leaving the fungi7. Escherichia coli8. The T bacteriophages9. Temperate phage and transduction10. DNA11. Prokaryotes take center stage12. Prokaryotes: Later contributions13. Cytoplasmic inheritance: The ciliates14. Organelle genetics: Yeast and Chlamydomonas15. Yeast becomes a supermodel16. The Filamentous fungi: Eclipse and renewal17. The role of biochemistry18. Genomics19. The age of model organismsAppendix 1. Life cycles and genetic principlesAppendix 2. Macromolecules and the Central DogmaAppendix 3. Genetic engineeringNotesReferencesName indexSubject index