The Oxford Handbook of the Auditory Brainstem / Edition 1

by Karl Kandler

Overview

The Oxford Handbook of The Auditory Brainstem provides an introduction as well as an in-depth reference to the organization and function of ascending and descending auditory pathways in the mammalian brainstem. Individual chapters are organized along the auditory pathway beginning with the cochlea and ending with the auditory midbrain. Each chapter provides an introduction to the respective area, and summarizes our current knowledge before discussing disputes and challenges the field currently faces.

A major emphasis throughout this book is on the numerous forms of plasticity that are increasingly observed in many areas of the auditory brainstem. Several chapters focus on neuronal modulation of function and synaptic, neuronal, and circuit plasticity, especially under circumstances when they occur most prominently: during development, aging, and following peripheral hearing loss. In addition, the book addresses the role of trauma-induced maladaptive plasticity with respect to its contribution in generating central hearing dysfunction such as hyperacusis and tinnitus.

The book is intended for students and postdocs starting in the auditory field, and researchers of related fields who wish to get an authoritative and up-to-date summary of the current state of auditory brainstem research. For clinical practitioners in audiology, otolaryngology, and neurology, the book is a valuable resource of information about the neuronal mechanisms that are major candidates for the generation of central hearing dysfunction.

Product Details

ISBN-13:	9780190849061
Publisher:	Oxford University Press
Publication date:	09/19/2019
Series:	Oxford Handbooks
Pages:	824
Product dimensions:	9.80(w) x 7.00(h) x 1.80(d)

About the Author

Karl Kandler is Professor of Neurobiology, Otolaryngology, and Bioengineering at the University of Pittsburgh, Pennsylvania, USA. He was born in Germany where he studied Biology at the University of Regensburg and the Eberhard Karls University of Tübingen, from which he graduated 1993 with a PhD. From 1993 to 1997, he performed postdoctoral research with Lawrence C. Katz at Howard Hughes Medical Institute and Duke University. Since 1998, Dr. Kandler is a faculty in the School of Medicine at the University of Pittsburgh investigating the development and plasticity of auditory circuits in the mammalian brain. From 2007 to 2017, he established and directed the auditory research group in the department of otolaryngology at this institution. In addition, Karl Kandler is a faculty member of the Center for the Neural Basis of Cognition and an adjunct Professor in the Department of Biological Sciences, Carnegie Mellon University.

Table of Contents

About the Editor
Contributors
Introduction and Overview

1. Wiring the Cochlea for Sound Perception
Brikha R. Shrestha and Lisa V. Goodrich
2. The Diversified Form and Function of Cochlear Afferents
Paul Albert Fuchs
3. Efferent Innervation to the Cochlea
Ana Belén Elgoyhen, Carolina Wedemeyer, and Mariano N. Di Guilmi
4. The Cochlear Nuclei: Synaptic Plasticity in Circuits and Synapses in the Ventral Cochlear Nuclei
Donata Oertel, Xiao-Jie Cao, and Alberto Recio-Spinoso
5. In Vitro Studies of Neuromodulation and Plasticity in the Dorsal Cochlear Nucleus
Laurence O. Trussell
6. Molecular and Structural Changes in the Cochlear Nucleus in Response to Hearing Loss
Maria E. Rubio
7. Age-Related and Noise-Induced Hearing Loss: Central Consequences in the Ventral Cochlear Nucleus
Ruili Xie, Tessa-Jonne F. Ropp, Michael R. Kasten, and Paul B. Manis
8. The Cochlear Nucleus as a Generator of Tinnitus-Related Signals
J.A. Kaltenbach and D.A. Godfrey
9. Multimodal Inputs to the Cochlear Nucleus and Their Role in the Generation of Tinnitus
Susan E. Shore and David T. Martel
10. Perinatal Development of the Medial Nucleus of the Trapezoid Body
Shobhana Sivaramakrishnan, Ashley Brandebura, Paul Holcomb, Daniel Heller, Douglas Kolson, Dakota Jackson, Peter H. Mathers, and George A. Spirou
11. Extraction of Auditory Information by Modulation of Neuronal Ion Channels
Leonard K. Kaczmarek
12. The Medial Superior Olivary Nucleus: Meeting the Need for Speed
Benedikt Grothe, Christian Leibold, and Michael Pecka
13. Lateral Superior Olive: Organization, Development, and Plasticity
Eckhard Friauf, Elisa G. Krächan, and Nicolas I.C. Müller
14. The Superior Paraolivary Nucleus
Anna K. Magnusson and Marcelo Gómez-Álvarez
15. Perineuronal Nets in the Superior Olivary Complex: Development, Function and Plasticity
Markus Morawski and Mandy Sonntag
16. The Nuclei of the Lateral Lemniscus
Felix Felmy
17. Axon Trajectories in the Auditory Brainstem
Nell Beatty Cant
18. Neuron Types, Intrinsic Circuits, and Plasticity in the Inferior Colliculus
Tetsufumi Ito, Munenori Ono, and Douglas L. Oliver
19. Changes in the Inferior Colliculus Associated with Hearing Loss: Noise-Induced Hearing Loss, Age-Related Hearing Loss, Tinnitus and Hyperacusis
Alan R. Palmer and Joel I. Berger
20. Unifying the Midbrain: The Commissure of the Inferior Colliculus
Adrian Rees and Llwyd D. Orton
21. Neuromodulatory Feedback to the Inferior Colliculus
Laura Hurley
22. Descending Auditory Pathways and Plasticity
Brett R. Schofield and Nichole L. Beebe
23. Aging Processes in the Subcortical Auditory System
Donald M. Caspary and Daniel A. Llano
24. Glial Cells in the Auditory Brainstem
Giedre Milinkeviciute and Karina S. Cramer
25. Deviance Detection and Encoding Acoustic Regularity in the Auditory Midbrain
Manuel S. Malmierca, Guillermo V. Carbajal, and Carles Escera
26. Brainstem Encoding of Speech and Music Sounds in Humans
Nina Kraus and Trent Nicol
27. The Auditory Brainstem Implant: Restoration of Speech Understanding from Electric Stimulation of the Human Cochlear Nucleus
Robert V. Shannon

Index