The Third Histamine Receptor: Selective Ligands as Potential Therapeutic Agents in CNS Disorders

by Divya Vohora (Editor)

Overview

Reveals an Emerging Avenue of Potential Treatments for a Host of Challenging Diseases and DisordersThe H3 receptor is known to play a major role in a range of CNS disorders, including those affecting cognitive functions such as ADHD and Alzheimer's disease, as well as sleep disorders, obesity, epilepsy, schizophrenia, depression, and neurodege

Product Details

ISBN-13:	9781000687361
Publisher:	CRC Press
Publication date:	11/14/2008
Sold by:	Barnes & Noble
Format:	eBook
Pages:	400
File size:	9 MB

About the Author

Vohora, Divya

Table of Contents

INTRODUCTION. H3 Receptor Target: Past, Present, and Future Perspectives from Worldwide H3 Experts. The Third Histamine Receptor: From Discovery to Clinics, a Long- Lasting Love Story at INSERM and Bioprojet. Histamine as a Neurotransmitter. THE THIRD HISTAMINE RECEPTOR. Phylogeny, Gene Structure, Expression, and Signaling. Drug Discovery: From Hits to Clinical Candidates. Peripheral Actions and Therapeutic Potential in Periphery. THERAPEUTIC POTENTIAL IN CENTRAL NERVOUS SYSTEM DISORDERS. Cognitive Functions, Attention-Deficit Hyperactivity Disorders, and Alzheimer's Disease. Sleep Disorders. Obesity. Epilepsy. Schizophrenia. Other Central Nervous System Disorders.

What People are Saying About This

From the Publisher

… this book offers a key overview of the subject, useful not only to mature researchers but also all scientists who discover this field. … will certainly become a work of reference in this rapidly-growing domain.
—Dr. Laurent Provins, UCB Pharma (Belgium), in ChemMedChem 2009

Editorial Reviews

… this book offers a key overview of the subject, useful not only to mature researchers but also all scientists who discover this field. … will certainly become a work of reference in this rapidly-growing domain.
—Dr. Laurent Provins, UCB Pharma (Belgium), in ChemMedChem 2009

From the Publisher