Tissue Engineering II: Basics of Tissue Engineering and Tissue Applications / Edition 1

by Kyongbum Lee, David L. Kaplan

Overview

It is our pleasure to present this special volume on tissue engineering in the series Advances in Biochemical Engineering and Biotechnology. Thisvolume reffects the emergence of tissue engineering as a core discipline of modern biomedical engineering, and recognizes the growing synergies between the technological developments in biotechnology and biomedicine. Along this vein, the focusof thisvolume istoprovide abiotechnology driven perspective on cell engineering fundamentals while highlighting their significance in p- ducing functional tissues. Our aim is to present an overview of the state of the art of a selection of these technologies, punctuated with current applications in the research and development of cell-based therapies for human disease. To prepare this volume, we have solicited contributions from leaders and experts in their respective fields, ranging from biomaterials and bioreactors to gene delivery and metabolic engineering. Particular emphasis was placed on including reviews that discuss various aspects of the biochemical processes underlying cell function, such as signaling, growth, differentiation, and communication. The reviews of research topics cover two main areas: cel- lar and non-cellular components and assembly; evaluation and optimization of tissue function; and integrated reactor or implant system development for research and clinical applications. Many of the reviews illustrate how bioche- cal engineering methods are used to produce and characterize novel materials (e. g. genetically engineered natural polymers, synthetic scaffolds with ce- type specific attachment sites or inductive factors), whose unique properties enable increased levels of control over tissue development and architecture.

Product Details

ISBN-13:	9783540361855
Publisher:	Springer Berlin Heidelberg
Publication date:	12/20/2006
Series:	Advances in Biochemical Engineering/Biotechnology , #103
Edition description:	2007
Pages:	336
Product dimensions:	6.10(w) x 9.25(h) x (d)

Table of Contents

Controlling Tissue Microenvironments: Biomimetics, Transport Phenomena, and Reacting Systems.- Perfusion Effects and Hydrodynamics.- Biopreservation of Cells and Engineered Tissues.- Fabrication of Three-Dimensional Tissues.- Engineering Skin to Study Human Disease – Tissue Models for Cancer Biology and Wound Repair.- Gene-Modified Tissue-Engineered Skin: The Next Generation of Skin Substitutes.- Nanostructured Biomaterials for Tissue Engineering Bone.- Integration of Technologies for Hepatic Tissue Engineering.