Tissue Repair and Fibrosis: The Role of the Myofibroblast / Edition 1

by Alexis Desmouliere, Beatriz Tuchweber, A Desmouliere, J Pratt, H Cottier

Overview

Specialists from diverse disciplines discuss the important topics of Tissue Repair and Fibrosis. The Role of Myofibroblast. The Myofibroblast is implicated in many processes, such as tissue repair,fibrosis, and stromal reaction to tumors. This book seeks to provide an overview of the knowledge accumulated since this cell was first describes 25 years ago. Discussions focusses on three main topics: - Cellular and molecular biology of fibroblast and myofibroblasts - Wound healing: experimental models, and - Human fibrocontracted diseases.

Product Details

ISBN-13:	9783540652441
Publisher:	Springer-Verlag New York, LLC
Publication date:	04/28/1999
Series:	Current Topics in Pathology Series , #93
Edition description:	New Edition
Pages:	224
Product dimensions:	6.69(w) x 9.84(h) x (d)

About the Author

Desmouliere, Alexis (Universite Victor Segalen Bordeaux 2); Tuchweber, Beatriz (Univ of Montreal)

Table of Contents

Some Historical and Philosophical Reflections on the Myofibroblast Concept

G. Gabbiani

Transcriptional Regulation of the Desmin and SM22 Genes in Vascular Smooth Muscle Cells

M. Mericskay, Z. Li, D. Paulin

Modulation of Myofibroblast and Smooth-Muscle Phenotypes in the Lung

R. B. Low

Role of Platelet-Derived Growth Factors in Angiogenesis and Alveogenesis

P. Lindahl, H. Bostrom, L. Karlsson (et al.)

Transforming Growth Factor-(beta) Gene Transfer to the Lung Induces Myofibroblast Presence and Pulmonary Fibrosis

J. Gauldie, P. J. Sime, Z. Xing (et al.)

Transforming Growth Factor-(beta) Induction of (alpha)-Smooth Muscle Actin is Dependent on the Deformability of the Collagen Matrix

N. Narani, P. D. Arora, A. Lew (et al.)

Signal Transduction Pathways Activated During Fibroblast Contraction of Collagen Matrices

F. Grinnell

Extracellular Matrix, Integrins and Focal Adhesions

D. Dogic, B. Eckes, M. Aumailley

What Is New in Mechanical Properties of Tissue-Engineered Organs

F. A. Auger, F. Berthod, F. Goulet (et al.)

Fibroblast - Cytokine - Extracellular Matrix Interactions in Wound Repair

A. Simeon, F. Monier, H. Emonard (et al.)

Myofibroblastic Differentiation and Extracellular Matrix Deposition in Early Stages of Cholestatic Fibrosis in Rat Liver

B. Tuchweber, A. Desmouliere, A. M. A. Costa (et al.)

Gene Therapy of Wounds with Growth Factors

J. M. Davidson, J. S. Whitsitt, B. Pennington (et al.)

What's New in Human Wound-Healing Myofibroblasts?

V. Moulin, D. Garrel, F. A. Auger (et al.)

The Myofibroblast in Neoplasia

W. Schurch

The Concept of Organizing Pneumonia

J. F. Cordier

Endothelial Repair in Atherogenesis

A. I. Gotlieb, T. Y. J. Lee

Glomerulosclerosis: The Role of Interstitial Myofibroblasts in its Progression

M. El Nahas, E. C. Muchaneta-Kubara, N. Tamimi (et al.)

The Myofibroblast as an Inflammatory Cell in Pulmonary Fibrosis

S. H. Phan, K. Zhang, H. Y. Zhang (et al.)

Cell - Cell and Cell - Matrix Interactions During Breast Cancer Progression

A. Noel, F. Kebers, E. Maquoi (et al.)

Hepatocyte Growth Factor Secreted by Human Liver Myofibroblasts Increases Invasiveness of Hepatocellular Carcinoma Cells

V. Neaud, S. Faouzi, J. Guirouilh (et al.)

Interplay of Matrix and Myofibroblasts During Hepatic Fibrogenesis

D. Schuppan, J. J. Cho, J. D. Jia (et al.)

Subject Index

Editorial Reviews

Reviewer: Alvin Telser, PhD (Northwestern University Feinberg School of Medicine)
Description: This volume in the series Current Topics in Pathology contains published reports of a meeting held in Lyon, France in December 1997.
Purpose: The book contains 21 chapters describing the current state of knowledge about the myofibroblast — a cell that was first described in 1971. A greater understanding of the role of this cell in normal and pathological processes is growing each year. This book is intended to put recent work in this area in a single volume. This is a worthwhile goal and is well achieved by the multiple authors.
Audience: The contents of this book are mostly intended for people knowledgeable in this area of cell biology and pathobiology, but it contains much information of interest to a more general research audience. The multiple authors of each chapter are well recognized authorities in this field.
Features: Most of the chapters contain a small number of illustrations of good quality. The book is well referenced and has a good general appearance.
Assessment: Each of the 21 chapters in this book discusses an interesting phase of research in the development, role and biology of the myofibroblast. It will be a useful reference volume for many researchers and should be on the shelves of life science libraries.

Doody's Review Service

4 Stars! from Doody

This volume in the series Current Topics in Pathology contains published reports of a meeting held in Lyon, France in December 1997. The book contains 21 chapters describing the current state of knowledge about the myofibroblast -- a cell that was first described in 1971. A greater understanding of the role of this cell in normal and pathological processes is growing each year. This book is intended to put recent work in this area in a single volume. This is a worthwhile goal and is well achieved by the multiple authors. The contents of this book are mostly intended for people knowledgeable in this area of cell biology and pathobiology, but it contains much information of interest to a more general research audience. The multiple authors of each chapter are well recognized authorities in this field. Most of the chapters contain a small number of illustrations of good quality. The book is well referenced and has a good general appearance. Each of the 21 chapters in this book discusses an interesting phase of research in the development, role and biology of the myofibroblast. It will be a useful reference volume for many researchers and should be on the shelves of life science libraries.

Alvin Telser